The effect of high-fat diet consumption on appetitive instrumental behavior in rats

Frédéric Tantot, Shauna L. Parkes, Alain R. Marchand, Chloé Boitard, Fabien Naneix, Sophie Layé, Pierre Trifilieff, Etienne Coutureau, Guillaume Ferreira*

*Corresponding author for this work

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Evidence now indicates that the chronic consumption of high-calorie foods, such as a high-fat diet (HFD), is associated with impaired control over food-seeking, yet the extent of this alteration is not fully understood. Using different reinforcement schedules, we evaluated whether HFD intake from weaning to adulthood modifies instrumental responding and induces a shift from goal-directed actions to habitual responding. We first observed reduced instrumental performance and motivation for a food reward in HFD-fed rats trained under schedules of reinforcement that facilitate habitual responding [Random Interval (RI)]. However, this deficit was alleviated if rats trained under RI were subsequently trained with reinforcement schedules that promote goal-directed strategies [Random Ratio (RR)]. Using an outcome devaluation procedure, we then demonstrated that consumption of a HFD promoted habitual behavior in rats trained under RI but not RR schedules. Finally, extended HFD exposure did not interfere with the ability of RR training to overcome impaired RI instrumental performance and to favor goal-directed behavior. These results indicate that chronic consumption of a HFD changes the co-ordination of goal-directed actions and habits and that alteration of food-seeking may be reversed under particular behavioral conditions.

Original languageEnglish
Pages (from-to)203-211
Number of pages9
JournalAppetite
Volume108
Early online date3 Oct 2016
DOIs
Publication statusPublished - 1 Jan 2017

Keywords

  • Action
  • Diet
  • Habit
  • Obesity
  • Operant conditioning
  • Outcome devaluation

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  • Activities

    • 1 Conference presentation
    • 1 Oral presentation

    Feed your teenage brain: impact of food diets during adolescence on dopamine circuits and functions

    Fabien Naneix (Speaker)

    23 Sep 2019

    Activity: Talk, presentation, public lecture, public engagement, outreach and knowledge exchangeConference presentation

    Feed your teenage brain: how food diet during adolescence can affect cognitive and brain development

    Fabien Naneix (Speaker)

    2017

    Activity: Talk, presentation, public lecture, public engagement, outreach and knowledge exchangeOral presentation

    Cite this

    Tantot, F., Parkes, S. L., Marchand, A. R., Boitard, C., Naneix, F., Layé, S., Trifilieff, P., Coutureau, E., & Ferreira, G. (2017). The effect of high-fat diet consumption on appetitive instrumental behavior in rats. Appetite, 108, 203-211. https://doi.org/10.1016/j.appet.2016.10.001