The effect of high intensity interval exercise on postprandial triacylglycerol and leukocyte activation - monitored for 48h post exercise

Brendan Morris Gabriel, Jamie Pugh, Valerie Pruneta-Deloche, Philippe Moulin, Aivaras Ratkevicius, Stuart Robert Gray

Research output: Contribution to journalArticle

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Abstract

Postprandial phenomenon are thought to contribute to atherogenesis alongside activation of the immune system. A single bout of high intensity interval exercise attenuates postprandial triacylglycerol (TG), although the longevity and mechanisms underlying this observation are unknown. The aims of this study were to determine whether this attenuation in postprandial TG remained 2 days after high intensity interval exercise, to monitor markers of leukocyte activation and investigate the underlying mechanisms. Eight young men each completed two three day trials. On day 1: subjects rested (Control) or performed 5 x 30 s maximal sprints (high intensity interval exercise). On day 2 and 3 subjects consumed high fat meals for breakfast and 3 h later for lunch. Blood samples were taken at various times and analysed for TG, glucose and TG-rich lipoprotein (TRL)-bound LPL-dependent TRL-TG hydrolysis (LTTH). Flow cytometry was used to evaluate granulocyte, monocyte and lymphocyte CD11b and CD36 expression. On day 2 after high intensity interval exercise TG area under the curve was lower (P
Original languageEnglish
Article numbere82669
Number of pages9
JournalPloS ONE
Volume8
Issue number12
DOIs
Publication statusPublished - 9 Dec 2013

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leukocytes
Triglycerides
exercise
Leukocytes
Chemical activation
triacylglycerols
Exercise
lipoproteins
Lipoproteins
atherogenesis
Lunch
lunch
Breakfast
Lymphocytes
Flow cytometry
breakfast
Immune system
granulocytes
meals (menu)
Granulocytes

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The effect of high intensity interval exercise on postprandial triacylglycerol and leukocyte activation - monitored for 48h post exercise. / Gabriel, Brendan Morris; Pugh, Jamie; Pruneta-Deloche, Valerie; Moulin, Philippe; Ratkevicius, Aivaras; Gray, Stuart Robert.

In: PloS ONE, Vol. 8, No. 12, e82669, 09.12.2013.

Research output: Contribution to journalArticle

Gabriel, Brendan Morris ; Pugh, Jamie ; Pruneta-Deloche, Valerie ; Moulin, Philippe ; Ratkevicius, Aivaras ; Gray, Stuart Robert. / The effect of high intensity interval exercise on postprandial triacylglycerol and leukocyte activation - monitored for 48h post exercise. In: PloS ONE. 2013 ; Vol. 8, No. 12.
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