The effect of long saphenous vein stripping on quality of life

R. K. MacKenzie, A. Paisley, P. L. Allan, Amanda Jane Lee, C. V. Ruckley, A. W. Bradbury

Research output: Contribution to journalArticle

121 Citations (Scopus)

Abstract

Purpose: Long saphenous vein (LSV) stripping in the treatment of varicose veins may reduce the recurrence of varices but may also increase morbidity rates. The effect of stripping on health-related quality of life (HRQoL) is unknown. The aim of this study was to examine the effect of LSV surgery, with and without successful stripping, on HRQoL.

Methods: This prospective study comprises 102 consecutive patients who underwent varicose vein surgery that included attempted stripping of the LSV to the knee. HRQoL was assessed before surgery and at 4 weeks, 6 months, and 2 years after surgery with the Aberdeen varicose vein severity score (AVSS; disease-specific) and the Short-Form 36 (SF-36; generic). Patients defined as stripped were those in whom complete thigh stripping to the knee was confirmed with postoperative duplex scanning at 2 years. Patients defined as incompletely stripped were those in whom any LSV remnant was found in the thigh after surgery. Deep venous reflux (DVR) was defined as reflux of 0.5 seconds or more in at least the popliteal vein.

Results: Sixty-six of 102 patients (65%) provided complete HRQoL data at all four time points. At baseline, there was no significant difference between patients who were stripped (n = 25) and incompletely stripped (n = 41) in terms of AVSS, SF-36, age, gender, DVR, or CEAP grade. Significantly more patients in the incompletely stripped group underwent surgery for recurrent disease (29/41, 71%, versus 8/25; 32%; P = .002, with chi(2) test). Both groups gained significant improvements in AVSS scores for as much as 2 years. After adjustment for recurrent disease, stripping conferred additional benefit in terms of AVSS at 6 months (median [interquartile range]) (9 [4 to 16] versus 15 [9 to 24]; P = .031) and 2 years (7 [2 to 10] versus 9 [5 to 15]; P = .014), which was statistically significant in patients without preoperative DVR but not significant in patients with preoperative DVR SF-36 scores were not affected by stripping.

Conclusion: LSV surgery leads to a significant improvement in disease-specific HRQoL for as much as 2 years. In patients without DVR, stripping to the knee confers additional benefit.

Original languageEnglish
Pages (from-to)1197-1203
Number of pages6
JournalJournal of Vascular Surgery
Volume35
Issue number6
DOIs
Publication statusPublished - Jun 2002

Keywords

  • RECURRENT VARICOSE-VEINS
  • DEEP VENOUS REFLUX
  • RANDOMIZED TRIAL
  • EDINBURGH VEIN
  • SURGERY
  • SF-36
  • QUESTIONNAIRE
  • SYMPTOMS

Cite this

MacKenzie, R. K., Paisley, A., Allan, P. L., Lee, A. J., Ruckley, C. V., & Bradbury, A. W. (2002). The effect of long saphenous vein stripping on quality of life. Journal of Vascular Surgery, 35(6), 1197-1203. https://doi.org/10.1067/mva.2002.121985

The effect of long saphenous vein stripping on quality of life. / MacKenzie, R. K.; Paisley, A.; Allan, P. L.; Lee, Amanda Jane; Ruckley, C. V.; Bradbury, A. W.

In: Journal of Vascular Surgery, Vol. 35, No. 6, 06.2002, p. 1197-1203.

Research output: Contribution to journalArticle

MacKenzie, RK, Paisley, A, Allan, PL, Lee, AJ, Ruckley, CV & Bradbury, AW 2002, 'The effect of long saphenous vein stripping on quality of life', Journal of Vascular Surgery, vol. 35, no. 6, pp. 1197-1203. https://doi.org/10.1067/mva.2002.121985
MacKenzie, R. K. ; Paisley, A. ; Allan, P. L. ; Lee, Amanda Jane ; Ruckley, C. V. ; Bradbury, A. W. / The effect of long saphenous vein stripping on quality of life. In: Journal of Vascular Surgery. 2002 ; Vol. 35, No. 6. pp. 1197-1203.
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abstract = "Purpose: Long saphenous vein (LSV) stripping in the treatment of varicose veins may reduce the recurrence of varices but may also increase morbidity rates. The effect of stripping on health-related quality of life (HRQoL) is unknown. The aim of this study was to examine the effect of LSV surgery, with and without successful stripping, on HRQoL.Methods: This prospective study comprises 102 consecutive patients who underwent varicose vein surgery that included attempted stripping of the LSV to the knee. HRQoL was assessed before surgery and at 4 weeks, 6 months, and 2 years after surgery with the Aberdeen varicose vein severity score (AVSS; disease-specific) and the Short-Form 36 (SF-36; generic). Patients defined as stripped were those in whom complete thigh stripping to the knee was confirmed with postoperative duplex scanning at 2 years. Patients defined as incompletely stripped were those in whom any LSV remnant was found in the thigh after surgery. Deep venous reflux (DVR) was defined as reflux of 0.5 seconds or more in at least the popliteal vein.Results: Sixty-six of 102 patients (65{\%}) provided complete HRQoL data at all four time points. At baseline, there was no significant difference between patients who were stripped (n = 25) and incompletely stripped (n = 41) in terms of AVSS, SF-36, age, gender, DVR, or CEAP grade. Significantly more patients in the incompletely stripped group underwent surgery for recurrent disease (29/41, 71{\%}, versus 8/25; 32{\%}; P = .002, with chi(2) test). Both groups gained significant improvements in AVSS scores for as much as 2 years. After adjustment for recurrent disease, stripping conferred additional benefit in terms of AVSS at 6 months (median [interquartile range]) (9 [4 to 16] versus 15 [9 to 24]; P = .031) and 2 years (7 [2 to 10] versus 9 [5 to 15]; P = .014), which was statistically significant in patients without preoperative DVR but not significant in patients with preoperative DVR SF-36 scores were not affected by stripping.Conclusion: LSV surgery leads to a significant improvement in disease-specific HRQoL for as much as 2 years. In patients without DVR, stripping to the knee confers additional benefit.",
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T1 - The effect of long saphenous vein stripping on quality of life

AU - MacKenzie, R. K.

AU - Paisley, A.

AU - Allan, P. L.

AU - Lee, Amanda Jane

AU - Ruckley, C. V.

AU - Bradbury, A. W.

PY - 2002/6

Y1 - 2002/6

N2 - Purpose: Long saphenous vein (LSV) stripping in the treatment of varicose veins may reduce the recurrence of varices but may also increase morbidity rates. The effect of stripping on health-related quality of life (HRQoL) is unknown. The aim of this study was to examine the effect of LSV surgery, with and without successful stripping, on HRQoL.Methods: This prospective study comprises 102 consecutive patients who underwent varicose vein surgery that included attempted stripping of the LSV to the knee. HRQoL was assessed before surgery and at 4 weeks, 6 months, and 2 years after surgery with the Aberdeen varicose vein severity score (AVSS; disease-specific) and the Short-Form 36 (SF-36; generic). Patients defined as stripped were those in whom complete thigh stripping to the knee was confirmed with postoperative duplex scanning at 2 years. Patients defined as incompletely stripped were those in whom any LSV remnant was found in the thigh after surgery. Deep venous reflux (DVR) was defined as reflux of 0.5 seconds or more in at least the popliteal vein.Results: Sixty-six of 102 patients (65%) provided complete HRQoL data at all four time points. At baseline, there was no significant difference between patients who were stripped (n = 25) and incompletely stripped (n = 41) in terms of AVSS, SF-36, age, gender, DVR, or CEAP grade. Significantly more patients in the incompletely stripped group underwent surgery for recurrent disease (29/41, 71%, versus 8/25; 32%; P = .002, with chi(2) test). Both groups gained significant improvements in AVSS scores for as much as 2 years. After adjustment for recurrent disease, stripping conferred additional benefit in terms of AVSS at 6 months (median [interquartile range]) (9 [4 to 16] versus 15 [9 to 24]; P = .031) and 2 years (7 [2 to 10] versus 9 [5 to 15]; P = .014), which was statistically significant in patients without preoperative DVR but not significant in patients with preoperative DVR SF-36 scores were not affected by stripping.Conclusion: LSV surgery leads to a significant improvement in disease-specific HRQoL for as much as 2 years. In patients without DVR, stripping to the knee confers additional benefit.

AB - Purpose: Long saphenous vein (LSV) stripping in the treatment of varicose veins may reduce the recurrence of varices but may also increase morbidity rates. The effect of stripping on health-related quality of life (HRQoL) is unknown. The aim of this study was to examine the effect of LSV surgery, with and without successful stripping, on HRQoL.Methods: This prospective study comprises 102 consecutive patients who underwent varicose vein surgery that included attempted stripping of the LSV to the knee. HRQoL was assessed before surgery and at 4 weeks, 6 months, and 2 years after surgery with the Aberdeen varicose vein severity score (AVSS; disease-specific) and the Short-Form 36 (SF-36; generic). Patients defined as stripped were those in whom complete thigh stripping to the knee was confirmed with postoperative duplex scanning at 2 years. Patients defined as incompletely stripped were those in whom any LSV remnant was found in the thigh after surgery. Deep venous reflux (DVR) was defined as reflux of 0.5 seconds or more in at least the popliteal vein.Results: Sixty-six of 102 patients (65%) provided complete HRQoL data at all four time points. At baseline, there was no significant difference between patients who were stripped (n = 25) and incompletely stripped (n = 41) in terms of AVSS, SF-36, age, gender, DVR, or CEAP grade. Significantly more patients in the incompletely stripped group underwent surgery for recurrent disease (29/41, 71%, versus 8/25; 32%; P = .002, with chi(2) test). Both groups gained significant improvements in AVSS scores for as much as 2 years. After adjustment for recurrent disease, stripping conferred additional benefit in terms of AVSS at 6 months (median [interquartile range]) (9 [4 to 16] versus 15 [9 to 24]; P = .031) and 2 years (7 [2 to 10] versus 9 [5 to 15]; P = .014), which was statistically significant in patients without preoperative DVR but not significant in patients with preoperative DVR SF-36 scores were not affected by stripping.Conclusion: LSV surgery leads to a significant improvement in disease-specific HRQoL for as much as 2 years. In patients without DVR, stripping to the knee confers additional benefit.

KW - RECURRENT VARICOSE-VEINS

KW - DEEP VENOUS REFLUX

KW - RANDOMIZED TRIAL

KW - EDINBURGH VEIN

KW - SURGERY

KW - SF-36

KW - QUESTIONNAIRE

KW - SYMPTOMS

U2 - 10.1067/mva.2002.121985

DO - 10.1067/mva.2002.121985

M3 - Article

VL - 35

SP - 1197

EP - 1203

JO - Journal of Vascular Surgery

JF - Journal of Vascular Surgery

SN - 0741-5214

IS - 6

ER -