The effect of tetronasin and monensin on fermentation, microbial numbers and the development of ionophore-resistant bacteria in the rumen

C. J. Newbold, R. J. Wallace, N. D. Walker

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

The Gram-negative rumen bacteria Fibrobacter succinogenes S85, Prevotella ruminicola M384 and Veillonella parvula L59 were grown in media containing successively increasing concentrations of the ionophores, monensin and tetronasin. All three species became more resistant to the ionophore with which they were grown. Increased resistance to one ionophore caused increased resistance to the other, and cross-resistance to another ionophore-lasalocid-and an antibiotic-avoparcin. Recovery of tetronasin-resistant bacteria from the rumen of monensin-fed sheep increased and vice versa, indicating that similar cross-resistance occurred in vivo.
Original languageEnglish
Pages (from-to)129-134
Number of pages6
JournalJournal of Applied Bacteriology
Volume75
Issue number2
DOIs
Publication statusPublished - Aug 1993

Fingerprint Dive into the research topics of 'The effect of tetronasin and monensin on fermentation, microbial numbers and the development of ionophore-resistant bacteria in the rumen'. Together they form a unique fingerprint.

  • Cite this