The effect of tetronasin and monensin on fermentation, microbial numbers and the development of ionophore-resistant bacteria in the rumen

C. J. Newbold, R. J. Wallace, N. D. Walker

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

The Gram-negative rumen bacteria Fibrobacter succinogenes S85, Prevotella ruminicola M384 and Veillonella parvula L59 were grown in media containing successively increasing concentrations of the ionophores, monensin and tetronasin. All three species became more resistant to the ionophore with which they were grown. Increased resistance to one ionophore caused increased resistance to the other, and cross-resistance to another ionophore-lasalocid-and an antibiotic-avoparcin. Recovery of tetronasin-resistant bacteria from the rumen of monensin-fed sheep increased and vice versa, indicating that similar cross-resistance occurred in vivo.
Original languageEnglish
Pages (from-to)129-134
Number of pages6
JournalJournal of Applied Bacteriology
Volume75
Issue number2
DOIs
Publication statusPublished - Aug 1993

Fingerprint

Monensin
Ionophores
Rumen
Fermentation
Bacteria
Prevotella ruminicola
Fibrobacter
Lasalocid
Veillonella
Gram-Negative Bacteria
Sheep
Anti-Bacterial Agents
tetronasin

Cite this

The effect of tetronasin and monensin on fermentation, microbial numbers and the development of ionophore-resistant bacteria in the rumen. / Newbold, C. J.; Wallace, R. J.; Walker, N. D.

In: Journal of Applied Bacteriology, Vol. 75, No. 2, 08.1993, p. 129-134.

Research output: Contribution to journalArticle

@article{b1fce30a06d04e3290c223d72fc5ce53,
title = "The effect of tetronasin and monensin on fermentation, microbial numbers and the development of ionophore-resistant bacteria in the rumen",
abstract = "The Gram-negative rumen bacteria Fibrobacter succinogenes S85, Prevotella ruminicola M384 and Veillonella parvula L59 were grown in media containing successively increasing concentrations of the ionophores, monensin and tetronasin. All three species became more resistant to the ionophore with which they were grown. Increased resistance to one ionophore caused increased resistance to the other, and cross-resistance to another ionophore-lasalocid-and an antibiotic-avoparcin. Recovery of tetronasin-resistant bacteria from the rumen of monensin-fed sheep increased and vice versa, indicating that similar cross-resistance occurred in vivo.",
author = "Newbold, {C. J.} and Wallace, {R. J.} and Walker, {N. D.}",
note = "Medline is the source for the MeSH terms of this document.",
year = "1993",
month = "8",
doi = "10.1111/j.1365-2672.1993.tb02757.x",
language = "English",
volume = "75",
pages = "129--134",
journal = "Journal of Applied Bacteriology",
issn = "0021-8847",
publisher = "Wiley-Blackwell",
number = "2",

}

TY - JOUR

T1 - The effect of tetronasin and monensin on fermentation, microbial numbers and the development of ionophore-resistant bacteria in the rumen

AU - Newbold, C. J.

AU - Wallace, R. J.

AU - Walker, N. D.

N1 - Medline is the source for the MeSH terms of this document.

PY - 1993/8

Y1 - 1993/8

N2 - The Gram-negative rumen bacteria Fibrobacter succinogenes S85, Prevotella ruminicola M384 and Veillonella parvula L59 were grown in media containing successively increasing concentrations of the ionophores, monensin and tetronasin. All three species became more resistant to the ionophore with which they were grown. Increased resistance to one ionophore caused increased resistance to the other, and cross-resistance to another ionophore-lasalocid-and an antibiotic-avoparcin. Recovery of tetronasin-resistant bacteria from the rumen of monensin-fed sheep increased and vice versa, indicating that similar cross-resistance occurred in vivo.

AB - The Gram-negative rumen bacteria Fibrobacter succinogenes S85, Prevotella ruminicola M384 and Veillonella parvula L59 were grown in media containing successively increasing concentrations of the ionophores, monensin and tetronasin. All three species became more resistant to the ionophore with which they were grown. Increased resistance to one ionophore caused increased resistance to the other, and cross-resistance to another ionophore-lasalocid-and an antibiotic-avoparcin. Recovery of tetronasin-resistant bacteria from the rumen of monensin-fed sheep increased and vice versa, indicating that similar cross-resistance occurred in vivo.

UR - http://www.scopus.com/inward/record.url?scp=0027247836&partnerID=8YFLogxK

U2 - 10.1111/j.1365-2672.1993.tb02757.x

DO - 10.1111/j.1365-2672.1993.tb02757.x

M3 - Article

VL - 75

SP - 129

EP - 134

JO - Journal of Applied Bacteriology

JF - Journal of Applied Bacteriology

SN - 0021-8847

IS - 2

ER -