TY - JOUR
T1 - The effects of dietary and lifestyle interventions among pregnant women who are overweight or obese on longer-term maternal and early childhood outcomes
T2 - Protocol for an individual participant data (IPD) meta-analysis
AU - Dodd, Jodie M.
AU - Grivell, Rosalie M.
AU - Louise, Jennie
AU - Deussen, Andrea R.
AU - Giles, Lynne
AU - Mol, Ben W.
AU - Vinter, Christina
AU - Tanvig, Mette
AU - Jensen, Dorte Moller
AU - Bogaerts, Annick
AU - Devlieger, Roland
AU - Luoto, Riitta
AU - McAuliffe, Fionnuala
AU - Renault, Kristina
AU - Carlsen, Emma
AU - Geiker, Nina
AU - Poston, Lucilla
AU - Briley, Annette
AU - Thangaratinam, Shakila
AU - Rogozinska, Ewelina
AU - Owens, Julie A.
PY - 2017/3/9
Y1 - 2017/3/9
N2 - Background: The aim of this individual participant data meta-analysis (IPDMA) is to evaluate the effects of dietary and lifestyle interventions among pregnant women who are overweight or obese on later maternal and early childhood outcomes at ages 3-5 years. Methods/design: We will build on the established International Weight Management in Pregnancy (i-WIP) IPD Collaborative Network, having identified researchers who have conducted randomised dietary and lifestyle interventions among pregnant women who are overweight or obese, and where ongoing childhood follow-up of participants has been or is being undertaken. The primary maternal outcome is a diagnosis of maternal metabolic syndrome. The primary childhood outcome is BMI above 90%. We have identified 7 relevant trials, involving 5425 women who were overweight or obese during pregnancy, with approximately 3544 women and children with follow-up assessments available for inclusion in the meta-analysis. Discussion: The proposed IPDMA provides an opportunity to evaluate the effect of dietary and lifestyle interventions among pregnant women who are overweight or obese on later maternal and early childhood health outcomes, including risk of obesity. This knowledge is essential to effectively translate research findings into clinical practice and public health policy. Systematic review registration: This IPD has been prospectively registered (PROSPERO), ID number CRD42016047165.
AB - Background: The aim of this individual participant data meta-analysis (IPDMA) is to evaluate the effects of dietary and lifestyle interventions among pregnant women who are overweight or obese on later maternal and early childhood outcomes at ages 3-5 years. Methods/design: We will build on the established International Weight Management in Pregnancy (i-WIP) IPD Collaborative Network, having identified researchers who have conducted randomised dietary and lifestyle interventions among pregnant women who are overweight or obese, and where ongoing childhood follow-up of participants has been or is being undertaken. The primary maternal outcome is a diagnosis of maternal metabolic syndrome. The primary childhood outcome is BMI above 90%. We have identified 7 relevant trials, involving 5425 women who were overweight or obese during pregnancy, with approximately 3544 women and children with follow-up assessments available for inclusion in the meta-analysis. Discussion: The proposed IPDMA provides an opportunity to evaluate the effect of dietary and lifestyle interventions among pregnant women who are overweight or obese on later maternal and early childhood health outcomes, including risk of obesity. This knowledge is essential to effectively translate research findings into clinical practice and public health policy. Systematic review registration: This IPD has been prospectively registered (PROSPERO), ID number CRD42016047165.
KW - Childhood obesity
KW - Individual participant data meta-analysis
KW - Pregnancy lifestyle intervention
UR - http://www.scopus.com/inward/record.url?scp=85014789486&partnerID=8YFLogxK
U2 - 10.1186/s13643-017-0442-6
DO - 10.1186/s13643-017-0442-6
M3 - Article
C2 - 28274270
AN - SCOPUS:85014789486
SN - 2046-4053
VL - 6
JO - Systematic reviews
JF - Systematic reviews
IS - 1
M1 - 51
ER -
