The effects of plant-based diets on pancreatic beta-cell function: A systematic review

Robert K Janko* (Corresponding Author), Philip Wilson, Chinedu Nworie

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Plant-based diets have been associated with improvements in blood glucose and HbA1c levels, as well as improvements in insulin resistance. This review aimed to systematically analyse the scientific literature on the effects of plant-based dietary interventions on pancreatic beta-cell function, as measured by insulin secretion. The three clinical trials that were included in the analysis showed a high risk of bias that was predominantly due to a lack of blinding in their designs. Compared with non-plant-based interventions, vegan and vegetarian diets showed a number of significant improvements in insulin secretion, HbA1c and weight loss across the studies. Larger randomised controlled trials with uniform measurements of beta-cell function would be beneficial to allow for quantitative analysis of pooled results.
Original languageEnglish
Number of pages7
JournalJournal of Diabetes Nursing
Volume25
Issue number2
Early online date23 Mar 2021
Publication statusPublished - Mar 2021

Keywords

  • Dietary interventions
  • Obesity, diet and lifestyle
  • Plant-based diets
  • Systematic Review

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