The evolutionary history of dogs in the Americas

Máire Ní Leathlobhair, Angela R Perri, Evan K Irving-Pease, Kelsey E Witt, Anna Linderholm, James Haile, Ophelie Lebrasseur, Carly Ameen, Jeffrey Blick, Adam R Boyko, Selina Brace, Yahaira Nunes Cortes, Susan J Crockford, Alison Devault, Evangelos A Dimopoulos, Morley Eldridge, Jacob Enk, Shyam Gopalakrishnan, Kevin Gori, Vaughan Grimes & 30 others Eric Guiry, Anders J Hansen, Ardern Hulme-Beaman, John Johnson, Andrew Kitchen, Aleksei K Kasparov, Young-Mi Kwon, Pavel A Nikolskiy, Carlos Peraza Lope, Aurélie Manin, Terrance Martin, Michael Meyer, Kelsey Noack Myers, Mark Omura, Jean-Marie Rouillard, Elena Y Pavlova, Paul Sciulli, Mikkel-Holger S Sinding, Andrea Strakova, Varvara V Ivanova, Christopher Widga, Eske Willerslev, Vladimir V Pitulko, Ian Barnes, M Thomas P Gilbert, Keith M Dobney, Ripan S Malhi, Elizabeth P Murchison, Greger Larson, Laurent A F Frantz

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Dogs were present in the Americas before the arrival of European colonists, but the origin and fate of these precontact dogs are largely unknown. We sequenced 71 mitochondrial and 7 nuclear genomes from ancient North American and Siberian dogs from time frames spanning ~9000 years. Our analysis indicates that American dogs were not derived from North American wolves. Instead, American dogs form a monophyletic lineage that likely originated in Siberia and dispersed into the Americas alongside people. After the arrival of Europeans, native American dogs almost completely disappeared, leaving a minimal genetic legacy in modern dog populations. The closest detectable extant lineage to precontact American dogs is the canine transmissible venereal tumor, a contagious cancer clone derived from an individual dog that lived up to 8000 years ago.

Original languageEnglish
Pages (from-to)81-85
Number of pages5
JournalScience
Volume361
Issue number6397
DOIs
Publication statusPublished - 6 Jul 2018

Fingerprint

History
Dogs
Veterinary Venereal Tumors
Siberia
North American Indians
Canidae
Clone Cells
Genome
Population
Neoplasms

Keywords

  • Journal Article
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

Cite this

Ní Leathlobhair, M., Perri, A. R., Irving-Pease, E. K., Witt, K. E., Linderholm, A., Haile, J., ... Frantz, L. A. F. (2018). The evolutionary history of dogs in the Americas. Science, 361(6397), 81-85. https://doi.org/10.1126/science.aao4776

The evolutionary history of dogs in the Americas. / Ní Leathlobhair, Máire; Perri, Angela R; Irving-Pease, Evan K; Witt, Kelsey E; Linderholm, Anna; Haile, James; Lebrasseur, Ophelie; Ameen, Carly; Blick, Jeffrey; Boyko, Adam R; Brace, Selina; Cortes, Yahaira Nunes; Crockford, Susan J; Devault, Alison; Dimopoulos, Evangelos A; Eldridge, Morley; Enk, Jacob; Gopalakrishnan, Shyam; Gori, Kevin; Grimes, Vaughan; Guiry, Eric; Hansen, Anders J; Hulme-Beaman, Ardern; Johnson, John; Kitchen, Andrew; Kasparov, Aleksei K; Kwon, Young-Mi; Nikolskiy, Pavel A; Lope, Carlos Peraza; Manin, Aurélie; Martin, Terrance; Meyer, Michael; Myers, Kelsey Noack; Omura, Mark; Rouillard, Jean-Marie; Pavlova, Elena Y; Sciulli, Paul; Sinding, Mikkel-Holger S; Strakova, Andrea; Ivanova, Varvara V; Widga, Christopher; Willerslev, Eske; Pitulko, Vladimir V; Barnes, Ian; Gilbert, M Thomas P; Dobney, Keith M; Malhi, Ripan S; Murchison, Elizabeth P; Larson, Greger; Frantz, Laurent A F.

In: Science, Vol. 361, No. 6397, 06.07.2018, p. 81-85.

Research output: Contribution to journalArticle

Ní Leathlobhair, M, Perri, AR, Irving-Pease, EK, Witt, KE, Linderholm, A, Haile, J, Lebrasseur, O, Ameen, C, Blick, J, Boyko, AR, Brace, S, Cortes, YN, Crockford, SJ, Devault, A, Dimopoulos, EA, Eldridge, M, Enk, J, Gopalakrishnan, S, Gori, K, Grimes, V, Guiry, E, Hansen, AJ, Hulme-Beaman, A, Johnson, J, Kitchen, A, Kasparov, AK, Kwon, Y-M, Nikolskiy, PA, Lope, CP, Manin, A, Martin, T, Meyer, M, Myers, KN, Omura, M, Rouillard, J-M, Pavlova, EY, Sciulli, P, Sinding, M-HS, Strakova, A, Ivanova, VV, Widga, C, Willerslev, E, Pitulko, VV, Barnes, I, Gilbert, MTP, Dobney, KM, Malhi, RS, Murchison, EP, Larson, G & Frantz, LAF 2018, 'The evolutionary history of dogs in the Americas', Science, vol. 361, no. 6397, pp. 81-85. https://doi.org/10.1126/science.aao4776
Ní Leathlobhair M, Perri AR, Irving-Pease EK, Witt KE, Linderholm A, Haile J et al. The evolutionary history of dogs in the Americas. Science. 2018 Jul 6;361(6397):81-85. https://doi.org/10.1126/science.aao4776
Ní Leathlobhair, Máire ; Perri, Angela R ; Irving-Pease, Evan K ; Witt, Kelsey E ; Linderholm, Anna ; Haile, James ; Lebrasseur, Ophelie ; Ameen, Carly ; Blick, Jeffrey ; Boyko, Adam R ; Brace, Selina ; Cortes, Yahaira Nunes ; Crockford, Susan J ; Devault, Alison ; Dimopoulos, Evangelos A ; Eldridge, Morley ; Enk, Jacob ; Gopalakrishnan, Shyam ; Gori, Kevin ; Grimes, Vaughan ; Guiry, Eric ; Hansen, Anders J ; Hulme-Beaman, Ardern ; Johnson, John ; Kitchen, Andrew ; Kasparov, Aleksei K ; Kwon, Young-Mi ; Nikolskiy, Pavel A ; Lope, Carlos Peraza ; Manin, Aurélie ; Martin, Terrance ; Meyer, Michael ; Myers, Kelsey Noack ; Omura, Mark ; Rouillard, Jean-Marie ; Pavlova, Elena Y ; Sciulli, Paul ; Sinding, Mikkel-Holger S ; Strakova, Andrea ; Ivanova, Varvara V ; Widga, Christopher ; Willerslev, Eske ; Pitulko, Vladimir V ; Barnes, Ian ; Gilbert, M Thomas P ; Dobney, Keith M ; Malhi, Ripan S ; Murchison, Elizabeth P ; Larson, Greger ; Frantz, Laurent A F. / The evolutionary history of dogs in the Americas. In: Science. 2018 ; Vol. 361, No. 6397. pp. 81-85.
@article{d0477a2c59ca4192866eba845ecd2943,
title = "The evolutionary history of dogs in the Americas",
abstract = "Dogs were present in the Americas before the arrival of European colonists, but the origin and fate of these precontact dogs are largely unknown. We sequenced 71 mitochondrial and 7 nuclear genomes from ancient North American and Siberian dogs from time frames spanning ~9000 years. Our analysis indicates that American dogs were not derived from North American wolves. Instead, American dogs form a monophyletic lineage that likely originated in Siberia and dispersed into the Americas alongside people. After the arrival of Europeans, native American dogs almost completely disappeared, leaving a minimal genetic legacy in modern dog populations. The closest detectable extant lineage to precontact American dogs is the canine transmissible venereal tumor, a contagious cancer clone derived from an individual dog that lived up to 8000 years ago.",
keywords = "Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.",
author = "{N{\'i} Leathlobhair}, M{\'a}ire and Perri, {Angela R} and Irving-Pease, {Evan K} and Witt, {Kelsey E} and Anna Linderholm and James Haile and Ophelie Lebrasseur and Carly Ameen and Jeffrey Blick and Boyko, {Adam R} and Selina Brace and Cortes, {Yahaira Nunes} and Crockford, {Susan J} and Alison Devault and Dimopoulos, {Evangelos A} and Morley Eldridge and Jacob Enk and Shyam Gopalakrishnan and Kevin Gori and Vaughan Grimes and Eric Guiry and Hansen, {Anders J} and Ardern Hulme-Beaman and John Johnson and Andrew Kitchen and Kasparov, {Aleksei K} and Young-Mi Kwon and Nikolskiy, {Pavel A} and Lope, {Carlos Peraza} and Aur{\'e}lie Manin and Terrance Martin and Michael Meyer and Myers, {Kelsey Noack} and Mark Omura and Jean-Marie Rouillard and Pavlova, {Elena Y} and Paul Sciulli and Sinding, {Mikkel-Holger S} and Andrea Strakova and Ivanova, {Varvara V} and Christopher Widga and Eske Willerslev and Pitulko, {Vladimir V} and Ian Barnes and Gilbert, {M Thomas P} and Dobney, {Keith M} and Malhi, {Ripan S} and Murchison, {Elizabeth P} and Greger Larson and Frantz, {Laurent A F}",
note = "licence to publish: http://www.sciencemag.org/site/feature/contribinfo/prep/lic_info.pdf",
year = "2018",
month = "7",
day = "6",
doi = "10.1126/science.aao4776",
language = "English",
volume = "361",
pages = "81--85",
journal = "Science",
issn = "0036-8075",
publisher = "AMER ASSOC ADVANCEMENT SCIENCE",
number = "6397",

}

TY - JOUR

T1 - The evolutionary history of dogs in the Americas

AU - Ní Leathlobhair, Máire

AU - Perri, Angela R

AU - Irving-Pease, Evan K

AU - Witt, Kelsey E

AU - Linderholm, Anna

AU - Haile, James

AU - Lebrasseur, Ophelie

AU - Ameen, Carly

AU - Blick, Jeffrey

AU - Boyko, Adam R

AU - Brace, Selina

AU - Cortes, Yahaira Nunes

AU - Crockford, Susan J

AU - Devault, Alison

AU - Dimopoulos, Evangelos A

AU - Eldridge, Morley

AU - Enk, Jacob

AU - Gopalakrishnan, Shyam

AU - Gori, Kevin

AU - Grimes, Vaughan

AU - Guiry, Eric

AU - Hansen, Anders J

AU - Hulme-Beaman, Ardern

AU - Johnson, John

AU - Kitchen, Andrew

AU - Kasparov, Aleksei K

AU - Kwon, Young-Mi

AU - Nikolskiy, Pavel A

AU - Lope, Carlos Peraza

AU - Manin, Aurélie

AU - Martin, Terrance

AU - Meyer, Michael

AU - Myers, Kelsey Noack

AU - Omura, Mark

AU - Rouillard, Jean-Marie

AU - Pavlova, Elena Y

AU - Sciulli, Paul

AU - Sinding, Mikkel-Holger S

AU - Strakova, Andrea

AU - Ivanova, Varvara V

AU - Widga, Christopher

AU - Willerslev, Eske

AU - Pitulko, Vladimir V

AU - Barnes, Ian

AU - Gilbert, M Thomas P

AU - Dobney, Keith M

AU - Malhi, Ripan S

AU - Murchison, Elizabeth P

AU - Larson, Greger

AU - Frantz, Laurent A F

N1 - licence to publish: http://www.sciencemag.org/site/feature/contribinfo/prep/lic_info.pdf

PY - 2018/7/6

Y1 - 2018/7/6

N2 - Dogs were present in the Americas before the arrival of European colonists, but the origin and fate of these precontact dogs are largely unknown. We sequenced 71 mitochondrial and 7 nuclear genomes from ancient North American and Siberian dogs from time frames spanning ~9000 years. Our analysis indicates that American dogs were not derived from North American wolves. Instead, American dogs form a monophyletic lineage that likely originated in Siberia and dispersed into the Americas alongside people. After the arrival of Europeans, native American dogs almost completely disappeared, leaving a minimal genetic legacy in modern dog populations. The closest detectable extant lineage to precontact American dogs is the canine transmissible venereal tumor, a contagious cancer clone derived from an individual dog that lived up to 8000 years ago.

AB - Dogs were present in the Americas before the arrival of European colonists, but the origin and fate of these precontact dogs are largely unknown. We sequenced 71 mitochondrial and 7 nuclear genomes from ancient North American and Siberian dogs from time frames spanning ~9000 years. Our analysis indicates that American dogs were not derived from North American wolves. Instead, American dogs form a monophyletic lineage that likely originated in Siberia and dispersed into the Americas alongside people. After the arrival of Europeans, native American dogs almost completely disappeared, leaving a minimal genetic legacy in modern dog populations. The closest detectable extant lineage to precontact American dogs is the canine transmissible venereal tumor, a contagious cancer clone derived from an individual dog that lived up to 8000 years ago.

KW - Journal Article

KW - Research Support, Non-U.S. Gov't

KW - Research Support, U.S. Gov't, Non-P.H.S.

U2 - 10.1126/science.aao4776

DO - 10.1126/science.aao4776

M3 - Article

VL - 361

SP - 81

EP - 85

JO - Science

JF - Science

SN - 0036-8075

IS - 6397

ER -