The genetic architecture of hip statistical shape models suggests that endochondral bone formation makes an important contribution to hip shape

D. Baird, D. S. Evans, J. S. Gregory, F. R. Saunders, C. V. Giuraniuc, R. J. Barr, R. M. Aspden, F. K. Kamanu, D. P. Kiel, E. S. Orwoll, S. R. Cummings, N. E. Lane, B. H. Mullins, F. M. Williams, B. Richards, S. G. Wilson, T. D. Spector, B. G. Faber, D. A. Lawlor, T. J. BeckD. M. Evans, L. Paternoster, D. Karasikl, J. H. Tobias

Research output: Contribution to journalAbstractpeer-review

Abstract

Abstracts from the 2018 OARSI World Congress on Osteoarthritis

Purpose: Variation in hip shape, as measured by statistical shapemodelling (SSM), is associated with prevalent hip osteoarthritis(OA) and progression of hip OA. However, little is known of thebiological processes which underlie hip shape. We aimed to identify these by studying the genetic architecture of DXA-derivedhip shape, using genome wide association study (GWAS) meta-analysis...
Original languageEnglish
Article number302
Pages (from-to)S157-S157
Number of pages1
JournalOsteoarthritis and Cartilage
Volume26
Publication statusPublished - Apr 2018
EventOARSI World Congress on Osteoarthritis - Promoting Clinical and Basic Research in Osteoarthritis - Liverpool
Duration: 26 Apr 201829 Apr 2018

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