TY - JOUR
T1 - The genetic history of Scandinavia from the Roman Iron Age to the present
AU - Rodríguez-Varela, Ricardo
AU - Moore, Kristjan H.S.
AU - Ebenesersdóttir, S. Sunna
AU - Kilinc, Gulsah Merve
AU - Kjellström, Anna
AU - Papmehl-Dufay, Ludvig
AU - Alfsdotter, Clara
AU - Berglund, Birgitta
AU - Alrawi, Loey
AU - Kashuba, Natalija
AU - Sobrado, Verónica
AU - Lagerholm, Vendela Kempe
AU - Gilbert, Edmund
AU - Cavalleri, Gianpiero L.
AU - Hovig, Eivind
AU - Kockum, Ingrid
AU - Olsson, Tomas
AU - Alfredsson, Lars
AU - Hansen, Thomas F.
AU - Werge, Thomas
AU - Munters, Arielle R.
AU - Bernhardsson, Carolina
AU - Skar, Birgitte
AU - Christophersen, Axel
AU - Turner-Walker, Gordon
AU - Gopalakrishnan, Shyam
AU - Daskalaki, Eva
AU - Omrak, Ayça
AU - Pérez-Ramallo, Patxi
AU - Skoglund, Pontus
AU - Girdland-Flink, Linus
AU - Gunnarsson, Fredrik
AU - Hedenstierna-Jonson, Charlotte
AU - Gilbert, M. Thomas P.
AU - Lidén, Kerstin
AU - Jakobsson, Mattias
AU - Einarsson, Lars
AU - Victor, Helena
AU - Krzewińska, Maja
AU - Zachrisson, Torun
AU - Storå, Jan
AU - Stefánsson, Kári
AU - Helgason, Agnar
AU - Götherström, Anders
N1 - The authors acknowledge support from the National Genomics Infrastructure in Stockholm funded by Science for Life Laboratory, the Knut and Alice Wallenberg Foundation and the Swedish Research Council, and SNIC/Uppsala Multidisciplinary Center for Advanced Computational Science for assistance with massively parallel sequencing and access to the UPPMAX computational infrastructure. We used resources from projects SNIC 2022/23-132, SNIC 2022/22-117, SNIC 2022/23-163, SNIC 2022/22-299, and SNIC 2021-2-17. This research was supported by the Swedish Research Council project ID 2019-00849_VR and ATLAS (Riksbankens Jubileumsfond). Part of the modern dataset was supported by a research grant from Science Foundation Ireland (SFI), grant number 16/RC/3948, and co-funded under the European Regional Development Fund and by FutureNeuro industry partners.
PY - 2023/1/5
Y1 - 2023/1/5
N2 - Summary We investigate a 2,000-year genetic transect through Scandinavia spanning the Iron Age to the present, based on 48 new and 249 published ancient genomes and genotypes from 16,638 modern individuals. We find regional variation in the timing and magnitude of gene flow from three sources: the eastern Baltic, the British-Irish Isles, and southern Europe. British-Irish ancestry was widespread in Scandinavia from the Viking period, whereas eastern Baltic ancestry is more localized to Gotland and central Sweden. In some regions, a drop in current levels of external ancestry suggests that ancient immigrants contributed proportionately less to the modern Scandinavian gene pool than indicated by the ancestry of genomes from the Viking and Medieval periods. Finally, we show that a north-south genetic cline that characterizes modern Scandinavians is mainly due to the differential levels of Uralic ancestry and that this cline existed in the Viking Age and possibly earlier.
AB - Summary We investigate a 2,000-year genetic transect through Scandinavia spanning the Iron Age to the present, based on 48 new and 249 published ancient genomes and genotypes from 16,638 modern individuals. We find regional variation in the timing and magnitude of gene flow from three sources: the eastern Baltic, the British-Irish Isles, and southern Europe. British-Irish ancestry was widespread in Scandinavia from the Viking period, whereas eastern Baltic ancestry is more localized to Gotland and central Sweden. In some regions, a drop in current levels of external ancestry suggests that ancient immigrants contributed proportionately less to the modern Scandinavian gene pool than indicated by the ancestry of genomes from the Viking and Medieval periods. Finally, we show that a north-south genetic cline that characterizes modern Scandinavians is mainly due to the differential levels of Uralic ancestry and that this cline existed in the Viking Age and possibly earlier.
KW - gene flow
KW - Scandinavian genetic structure
KW - Viking
KW - migration period
KW - human population genomics
U2 - 10.1016/j.cell.2022.11.024
DO - 10.1016/j.cell.2022.11.024
M3 - Article
C2 - 36608656
SN - 0092-8674
VL - 186
SP - 32-46.e1
JO - Cell
JF - Cell
IS - 1
ER -