The guidance of magnetic colloids in simulated tissues for targeted drug delivery

O. Rotariu, L. E. Udrea, Norval James Colin Strachan, V. Badescu

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

The delivery of anticancer agents delivered by magnetic carrier particles (MP) is an exciting new prospect in treating cancer. Here an experimental model is used to investigate the physical guidance of magnetic carrier colloids through simulated tissues. Using a gradient magnetic field, it was found that magnetic particles could be dispersed within a simulated diseased tissue in < 120 minutes. This treatment time depended on the magnetic field, the MP properties and the kind of tissue (interstitial space between the cells). These results indicate that the magnetic guidance of colloids has the potential for treating sub-surface cancers within the human body.

Original languageEnglish
Pages (from-to)942-945
Number of pages4
JournalJournal of Optoelectronics and Advanced Materials
Volume9
Issue number4
Publication statusPublished - Apr 2007

Keywords

  • magnetic drug targeting
  • magnetic particles
  • tissues
  • agar gels

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