The management of recurrent croup in children

Iain Rankin, S M Wang, A Waters, W A Clement, H Kubba

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

OBJECTIVE: To review the aetiology, investigation, diagnosis, treatment and clinical outcome of children with recurrent croup.

METHOD: Retrospective case note review of all children with recurrent croup referred to the otolaryngology service at our hospital from November 2002 to March 2011.

RESULTS: Ninety children with recurrent croup were identified. Twenty-five children (28 per cent) had anatomical airway abnormalities, of which 16 (18 per cent) demonstrated degrees of subglottic stenosis. Twenty-three children (26 per cent) had positive microlaryngobronchoscopy findings suggestive of reflux. Eleven children were treated for gastroesophageal reflux disease, 10 (91 per cent) of whom responded well to anti-reflux medication (p = 0.006). No cause was identified for 41 (45 per cent) of the children; this was the group most likely to continue having episodes of croup at follow up. One death occurred in this group.

CONCLUSION: Airway anomalies are common in children that present with recurrent croup. Laryngobronchoscopy allows identification of the cause of croup and enables a more accurate prognosis. In the current study, laryngobronchoscopy findings that indicated reflux were predictive of benefit from anti-reflux medications, whereas the clinical presentation of reflux was not. Routine measurement of immunoglobulin E and complement proteins did not appear to be helpful.

Original languageEnglish
Pages (from-to)494-500
Number of pages7
JournalJournal of Laryngology & Otology
Volume127
Issue number5
DOIs
Publication statusPublished - May 2013

Fingerprint

Croup
Otolaryngology
Gastroesophageal Reflux
Immunoglobulin E
Complement System Proteins
Pathologic Constriction

Keywords

  • Child
  • Child, Preschool
  • Croup
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Recurrence
  • Retrospective Studies
  • Journal Article

Cite this

Rankin, I., Wang, S. M., Waters, A., Clement, W. A., & Kubba, H. (2013). The management of recurrent croup in children. Journal of Laryngology & Otology, 127(5), 494-500. https://doi.org/10.1017/S0022215113000418

The management of recurrent croup in children. / Rankin, Iain; Wang, S M; Waters, A; Clement, W A; Kubba, H.

In: Journal of Laryngology & Otology, Vol. 127, No. 5, 05.2013, p. 494-500.

Research output: Contribution to journalArticle

Rankin, I, Wang, SM, Waters, A, Clement, WA & Kubba, H 2013, 'The management of recurrent croup in children', Journal of Laryngology & Otology, vol. 127, no. 5, pp. 494-500. https://doi.org/10.1017/S0022215113000418
Rankin I, Wang SM, Waters A, Clement WA, Kubba H. The management of recurrent croup in children. Journal of Laryngology & Otology. 2013 May;127(5):494-500. https://doi.org/10.1017/S0022215113000418
Rankin, Iain ; Wang, S M ; Waters, A ; Clement, W A ; Kubba, H. / The management of recurrent croup in children. In: Journal of Laryngology & Otology. 2013 ; Vol. 127, No. 5. pp. 494-500.
@article{6f1ed220422248cbb7900f26642ed449,
title = "The management of recurrent croup in children",
abstract = "OBJECTIVE: To review the aetiology, investigation, diagnosis, treatment and clinical outcome of children with recurrent croup.METHOD: Retrospective case note review of all children with recurrent croup referred to the otolaryngology service at our hospital from November 2002 to March 2011.RESULTS: Ninety children with recurrent croup were identified. Twenty-five children (28 per cent) had anatomical airway abnormalities, of which 16 (18 per cent) demonstrated degrees of subglottic stenosis. Twenty-three children (26 per cent) had positive microlaryngobronchoscopy findings suggestive of reflux. Eleven children were treated for gastroesophageal reflux disease, 10 (91 per cent) of whom responded well to anti-reflux medication (p = 0.006). No cause was identified for 41 (45 per cent) of the children; this was the group most likely to continue having episodes of croup at follow up. One death occurred in this group.CONCLUSION: Airway anomalies are common in children that present with recurrent croup. Laryngobronchoscopy allows identification of the cause of croup and enables a more accurate prognosis. In the current study, laryngobronchoscopy findings that indicated reflux were predictive of benefit from anti-reflux medications, whereas the clinical presentation of reflux was not. Routine measurement of immunoglobulin E and complement proteins did not appear to be helpful.",
keywords = "Child, Child, Preschool, Croup, Female, Humans, Infant, Infant, Newborn, Male, Recurrence, Retrospective Studies, Journal Article",
author = "Iain Rankin and Wang, {S M} and A Waters and Clement, {W A} and H Kubba",
year = "2013",
month = "5",
doi = "10.1017/S0022215113000418",
language = "English",
volume = "127",
pages = "494--500",
journal = "Journal of Laryngology & Otology",
issn = "0022-2151",
publisher = "Cambridge University Press",
number = "5",

}

TY - JOUR

T1 - The management of recurrent croup in children

AU - Rankin, Iain

AU - Wang, S M

AU - Waters, A

AU - Clement, W A

AU - Kubba, H

PY - 2013/5

Y1 - 2013/5

N2 - OBJECTIVE: To review the aetiology, investigation, diagnosis, treatment and clinical outcome of children with recurrent croup.METHOD: Retrospective case note review of all children with recurrent croup referred to the otolaryngology service at our hospital from November 2002 to March 2011.RESULTS: Ninety children with recurrent croup were identified. Twenty-five children (28 per cent) had anatomical airway abnormalities, of which 16 (18 per cent) demonstrated degrees of subglottic stenosis. Twenty-three children (26 per cent) had positive microlaryngobronchoscopy findings suggestive of reflux. Eleven children were treated for gastroesophageal reflux disease, 10 (91 per cent) of whom responded well to anti-reflux medication (p = 0.006). No cause was identified for 41 (45 per cent) of the children; this was the group most likely to continue having episodes of croup at follow up. One death occurred in this group.CONCLUSION: Airway anomalies are common in children that present with recurrent croup. Laryngobronchoscopy allows identification of the cause of croup and enables a more accurate prognosis. In the current study, laryngobronchoscopy findings that indicated reflux were predictive of benefit from anti-reflux medications, whereas the clinical presentation of reflux was not. Routine measurement of immunoglobulin E and complement proteins did not appear to be helpful.

AB - OBJECTIVE: To review the aetiology, investigation, diagnosis, treatment and clinical outcome of children with recurrent croup.METHOD: Retrospective case note review of all children with recurrent croup referred to the otolaryngology service at our hospital from November 2002 to March 2011.RESULTS: Ninety children with recurrent croup were identified. Twenty-five children (28 per cent) had anatomical airway abnormalities, of which 16 (18 per cent) demonstrated degrees of subglottic stenosis. Twenty-three children (26 per cent) had positive microlaryngobronchoscopy findings suggestive of reflux. Eleven children were treated for gastroesophageal reflux disease, 10 (91 per cent) of whom responded well to anti-reflux medication (p = 0.006). No cause was identified for 41 (45 per cent) of the children; this was the group most likely to continue having episodes of croup at follow up. One death occurred in this group.CONCLUSION: Airway anomalies are common in children that present with recurrent croup. Laryngobronchoscopy allows identification of the cause of croup and enables a more accurate prognosis. In the current study, laryngobronchoscopy findings that indicated reflux were predictive of benefit from anti-reflux medications, whereas the clinical presentation of reflux was not. Routine measurement of immunoglobulin E and complement proteins did not appear to be helpful.

KW - Child

KW - Child, Preschool

KW - Croup

KW - Female

KW - Humans

KW - Infant

KW - Infant, Newborn

KW - Male

KW - Recurrence

KW - Retrospective Studies

KW - Journal Article

U2 - 10.1017/S0022215113000418

DO - 10.1017/S0022215113000418

M3 - Article

VL - 127

SP - 494

EP - 500

JO - Journal of Laryngology & Otology

JF - Journal of Laryngology & Otology

SN - 0022-2151

IS - 5

ER -