The pathophysiology of heart failure with preserved ejection fraction: from molecular mechanisms to exercise haemodynamics

Thanh T Phan; Ganesh Nallur Shivu; Khalid Abozguia; John E Sanderson; Michael Frenneaux

doi:10.1016/j.ijcard.2011.06.113

The pathophysiology of heart failure with preserved ejection fraction: from molecular mechanisms to exercise haemodynamics

Thanh T Phan, Ganesh Nallur Shivu, Khalid Abozguia, John E Sanderson, Michael Frenneaux

Applied Medicine

Research output: Contribution to journal › Article › peer-review

37 Citations (Scopus)

Abstract

The pathophysiology of HfpEF is complex. In this review we discuss the molecular aspects of HfpEF as well as the profoundly disturbed haemodynamics with particular focus on exercise haemodynamic abnormalities.

Original language	English
Pages (from-to)	337-343
Number of pages	7
Journal	International Journal of Cardiology
Volume	158
Issue number	3
DOIs	https://doi.org/10.1016/j.ijcard.2011.06.113
Publication status	Published - 26 Jul 2012

Keywords

diastolic heart failure
exercise haemodynamics
large artery stiffness
left ventricular stiffness
ventricular-vascular coupling
hypertrophy

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10.1016/j.ijcard.2011.06.113

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title = "The pathophysiology of heart failure with preserved ejection fraction: from molecular mechanisms to exercise haemodynamics",

abstract = "The pathophysiology of HfpEF is complex. In this review we discuss the molecular aspects of HfpEF as well as the profoundly disturbed haemodynamics with particular focus on exercise haemodynamic abnormalities.",

keywords = "diastolic heart failure, exercise haemodynamics, large artery stiffness, left ventricular stiffness, ventricular-vascular coupling, hypertrophy",

author = "Phan, {Thanh T} and Shivu, {Ganesh Nallur} and Khalid Abozguia and Sanderson, {John E} and Michael Frenneaux",

note = "Copyright {\textcopyright} 2011. Published by Elsevier Ireland Ltd.",

year = "2012",

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T2 - from molecular mechanisms to exercise haemodynamics

AU - Phan, Thanh T

AU - Shivu, Ganesh Nallur

AU - Abozguia, Khalid

AU - Sanderson, John E

AU - Frenneaux, Michael

PY - 2012/7/26

Y1 - 2012/7/26

N2 - The pathophysiology of HfpEF is complex. In this review we discuss the molecular aspects of HfpEF as well as the profoundly disturbed haemodynamics with particular focus on exercise haemodynamic abnormalities.

AB - The pathophysiology of HfpEF is complex. In this review we discuss the molecular aspects of HfpEF as well as the profoundly disturbed haemodynamics with particular focus on exercise haemodynamic abnormalities.

KW - diastolic heart failure

KW - exercise haemodynamics

KW - large artery stiffness

KW - left ventricular stiffness

KW - ventricular-vascular coupling

KW - hypertrophy

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DO - 10.1016/j.ijcard.2011.06.113

M3 - Article

C2 - 21794933

VL - 158

SP - 337

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JO - International Journal of Cardiology

JF - International Journal of Cardiology

SN - 0167-5273

IS - 3

ER -

The pathophysiology of heart failure with preserved ejection fraction: from molecular mechanisms to exercise haemodynamics

Abstract

Keywords

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