Nodal involvement is one of the most significant prognostic factors in squamous cell carcinoma ( SCC) of the vulva. We conducted a retrospective analysis of 31 women with histologically node- negative SCC from a population- based cohort of Grampian women. Median follow- up was 42 months after radical vulvectomy with groin node dissection. In total, 13 women ( 42%) were found to have micrometastases on immunohistochemistry. The risk of recurrence was almost 20- fold higher in those with micrometastases compared to those without ( hazard ratio = 19.6 ( 95% CI 2.3 - 171).
|Number of pages||2|
|Journal||British Journal of Cancer|
|Publication status||Published - 2005|
- vulval cancer
- groin nodes
- SENTINEL LYMPH-NODE
- GROIN RECURRENCE