TY - JOUR
T1 - The Role of redo-Sentinel Lymph Node Biopsy in Patients With Prior Ipsilateral Breast Cancer Surgery
AU - Macnab, Margo Rose F.
AU - Slater, Gabrielle
AU - Fuller, Mairi
AU - Elsberger, Beatrix
AU - Lovell, Lesley
AU - Staff, Roger T.
AU - Masannat, Yazan A.
N1 - Acknowledgments
There is no funding for this project as this is a retrospective review of our practice. This project did not get any grants or funding in the public, commercial or a none profit sector. Open Access via Elsevier agreement.
PY - 2022/2/3
Y1 - 2022/2/3
N2 - Background: Sentinel Lymph Node Biopsy (SLNB) is used to stage the axilla, but there is limited data in patients with prior ipsilateral breast cancer. This study compares redo-SLNB (reSLNB) and Axillary node sample (ANS) in this sub-cohort of patients. Materials and Methods: This is a retrospective study looking at patients with a new ipsilateral primary or recurrence with history of breast-conserving surgery. Planned and performed surgery, patient demographics and previous treatments were recorded. Node positivity and success rate of reSLNB was analyzed. Results: A total of 86 patients were identified that had mastectomy for ipsilateral recurrent disease with radiologically negative axilla. Out of the 48 that had reSLNB, 35(72.9%) were successful. Nineteen percent of the reSLNB had positive axillae and 20% of the ANS patients. reSLNB success rate was significantly lower amongst patients with previous axillary surgery (P = .014) and previous positive nodes(P = .001). Conclusion: reSLNB should be considered to restage the axilla in patients with previous history of ipsilateral cancer especially that there is growing evidence showing good identification rate.
AB - Background: Sentinel Lymph Node Biopsy (SLNB) is used to stage the axilla, but there is limited data in patients with prior ipsilateral breast cancer. This study compares redo-SLNB (reSLNB) and Axillary node sample (ANS) in this sub-cohort of patients. Materials and Methods: This is a retrospective study looking at patients with a new ipsilateral primary or recurrence with history of breast-conserving surgery. Planned and performed surgery, patient demographics and previous treatments were recorded. Node positivity and success rate of reSLNB was analyzed. Results: A total of 86 patients were identified that had mastectomy for ipsilateral recurrent disease with radiologically negative axilla. Out of the 48 that had reSLNB, 35(72.9%) were successful. Nineteen percent of the reSLNB had positive axillae and 20% of the ANS patients. reSLNB success rate was significantly lower amongst patients with previous axillary surgery (P = .014) and previous positive nodes(P = .001). Conclusion: reSLNB should be considered to restage the axilla in patients with previous history of ipsilateral cancer especially that there is growing evidence showing good identification rate.
KW - Axillary node sample
KW - Axillary Surgery
KW - Breast cancer recurrence
KW - Breast surgery
KW - Sentinel node biopsy
UR - http://www.scopus.com/inward/record.url?scp=85126002966&partnerID=8YFLogxK
U2 - 10.1016/j.clbc.2022.01.012
DO - 10.1016/j.clbc.2022.01.012
M3 - Article
AN - SCOPUS:85126002966
JO - Clinical Breast Cancer
JF - Clinical Breast Cancer
SN - 1526-8209
ER -
