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The role of reductive and oxidative metabolism in the toxicity of mitoxantrone, adriamycin and menadione in human liver derived Hep G2 hepatoma cells
S J Duthie, M H Grant
Applied Health Sciences
The Rowett Institute of Nutrition and Health
Research output
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Contribution to journal
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Article
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peer-review
53
Citations (Scopus)
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Dive into the research topics of 'The role of reductive and oxidative metabolism in the toxicity of mitoxantrone, adriamycin and menadione in human liver derived Hep G2 hepatoma cells'. Together they form a unique fingerprint.
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Medicine & Life Sciences
Vitamin K 3
100%
Mitoxantrone
92%
Hep G2 Cells
75%
Doxorubicin
65%
Hepatocellular Carcinoma
57%
NAD(P)H Dehydrogenase (Quinone)
41%
Quinones
41%
Liver
36%
Electrons
34%
Mixed Function Oxygenases
32%
Dicumarol
21%
Metyrapone
20%
Nucleic Acid Synthesis Inhibitors
19%
Protein Synthesis Inhibitors
17%
Glutathione Reductase
17%
quinone
17%
Enzymes
15%
Cytochrome P-450 Enzyme System
13%
Catalase
13%
Oxidation-Reduction
13%
Reactive Oxygen Species
11%
Poisons
10%
Oxygen
10%
RNA
9%
Growth
7%
Proteins
5%