The Sinorhizobium meliloti LpxXL and AcpXL proteins play important roles in bacteroid development within alfalfa

Andreas F Haag, Silvia Wehmeier, Sebastian Beck, Victoria L Marlow, Vivien Fletcher, Euan K James, Gail P Ferguson

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35 Citations (Scopus)


Free-living Sinorhizobium meliloti lpxXL and acpXL mutants lack lipid A very-long-chain fatty acids (VLCFAs) and have reduced competitiveness in alfalfa. We demonstrate that LpxXL and AcpXL play important but distinct roles in bacteroid development and that LpxXL is essential for the modification of S. meliloti bacteroid lipid A with VLCFAs.
Original languageEnglish
Pages (from-to)4681-4686
Number of pages6
JournalJournal of Bacteriology
Issue number14
Early online date8 May 2009
Publication statusPublished - 15 Jul 2009



  • bacterial proteins
  • fatty acids
  • gene knockout techniques
  • lipid A
  • medicago sativa
  • Sinorhizobium meliloti

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