The value of archival tissue blocks in understanding breast cancer biology

Thomas Dowsett, Eldo Verghese, Steven Pollock, Jennifer Pollard, Judith Heads, Andrew Hanby, Valerie Speirs

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Pathological reporting of breast cancer has evolved alongside scientific advances. Such advances have led to recognition of different molecular classes of breast cancer resulting in improved disease management. The aim of this study was to establish whether these advances could be applied to archival breast cancer cases dating from the 1940s to assess historical trends. Important observations included the marked differences in pathological reporting, size of tumour and in ERα expression throughout the decades.

Original languageEnglish
Pages (from-to)272-275
Number of pages4
JournalJournal of Clinical Pathology
Volume67
Issue number3
Early online date29 Oct 2013
DOIs
Publication statusPublished - Mar 2014

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