The worm profits from undercharging

Ian Stansfield; Christopher G Proud

doi:10.1016/j.cmet.2009.03.007

The worm profits from undercharging

Ian Stansfield, Christopher G Proud

Medical Sciences

Research output: Contribution to journal › Article

Abstract

Hypoxia endangers the survival of cells and organisms. Mutations in an enzyme that attaches amino acids to tRNAs to supply protein synthesis confer resistance to hypoxia in C. elegans. By slowing down protein synthesis (a major consumer of energy), such mutations may save valuable energy and/or prevent accumulation of malfolded proteins.

Original language	English
Pages (from-to)	309-310
Number of pages	2
Journal	Cell Metabolism
Volume	9
Issue number	4
DOIs	https://doi.org/10.1016/j.cmet.2009.03.007
Publication status	Published - 8 Apr 2009

Keywords

animals
Caenorhabditis elegans
cell hypoxia
protein biosynthesis
thermodynamics

Access to Document

10.1016/j.cmet.2009.03.007

Cite this

@article{363940afa00f481287a5654aa6515941,

title = "The worm profits from undercharging",

abstract = "Hypoxia endangers the survival of cells and organisms. Mutations in an enzyme that attaches amino acids to tRNAs to supply protein synthesis confer resistance to hypoxia in C. elegans. By slowing down protein synthesis (a major consumer of energy), such mutations may save valuable energy and/or prevent accumulation of malfolded proteins.",

keywords = "animals, Caenorhabditis elegans, cell hypoxia, protein biosynthesis, thermodynamics",

author = "Ian Stansfield and Proud, {Christopher G}",

year = "2009",

month = apr,

day = "8",

doi = "10.1016/j.cmet.2009.03.007",

language = "English",

volume = "9",

pages = "309--310",

journal = "Cell Metabolism",

issn = "1932-7420",

publisher = "Cell Press",

number = "4",

}

TY - JOUR

T1 - The worm profits from undercharging

AU - Stansfield, Ian

AU - Proud, Christopher G

PY - 2009/4/8

Y1 - 2009/4/8

N2 - Hypoxia endangers the survival of cells and organisms. Mutations in an enzyme that attaches amino acids to tRNAs to supply protein synthesis confer resistance to hypoxia in C. elegans. By slowing down protein synthesis (a major consumer of energy), such mutations may save valuable energy and/or prevent accumulation of malfolded proteins.

AB - Hypoxia endangers the survival of cells and organisms. Mutations in an enzyme that attaches amino acids to tRNAs to supply protein synthesis confer resistance to hypoxia in C. elegans. By slowing down protein synthesis (a major consumer of energy), such mutations may save valuable energy and/or prevent accumulation of malfolded proteins.

KW - animals

KW - Caenorhabditis elegans

KW - cell hypoxia

KW - protein biosynthesis

KW - thermodynamics

U2 - 10.1016/j.cmet.2009.03.007

DO - 10.1016/j.cmet.2009.03.007

M3 - Article

C2 - 19356712

SN - 1932-7420

VL - 9

SP - 309

EP - 310

JO - Cell Metabolism

JF - Cell Metabolism

IS - 4

ER -

The worm profits from undercharging

Abstract

Keywords

Access to Document

Fingerprint

Cite this