Time-based prospective memory in children and adolescents with 22q11.2 deletion syndrome

Céline  Souchay; Lydia Dubourg; Nicola Ballhausen; Maude Schneider; Charline Cerf; Katharina Schnitzspahn; Laurence Faivre; Matthias Kliegel; Stephan Eliez

doi:10.1080/13854046.2017.1403652

Time-based prospective memory in children and adolescents with 22q11.2 deletion syndrome

Céline Souchay, Lydia Dubourg, Nicola Ballhausen, Maude Schneider, Charline Cerf, Katharina Schnitzspahn, Laurence Faivre, Matthias Kliegel, Stephan Eliez

Psychology

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

20 Downloads (Pure)

Abstract

Objective: 22q11.2 deletion syndrome, also known as velo-cardio-facial syndrome (VCFS) is a genetic disorder caused by a microdeletion on chromosome 22q11.2 and characterized by marked impairment in visual attention and executive function. The present study examined if this cognitive deficit extends to prospective memory (the type of memory involved in remembering to perform actions in the future).

Method: 20 participants with 22q11.2DS aged between 6 and 14 were included in the study as well as 22 typically developing individuals (TDC) aged 6 to 12. To measure prospective memory, participants were asked to play a driving game (the Dresden Cruiser, Voigt et al., 2014). This time-based prospective memory task required children to remember to refuel their car when the fuel level was low by pressing a refuel button while driving.

Results and Discussion: Participants with 22q11.2DS remembered less often to refuel the car. Furthermore, participants with 22q11.2DS checked the fuel gauge significantly less often than the controls.

Conclusions: Participants with 22q11.2DS therefore demonstrate difficulties completing a time-based prospective memory task. This can be explained by a generally less frequent time checking behaviour in comparison to TDC.

Original language	English
Pages (from-to)	981-992
Number of pages	12
Journal	Clinical Neuropsychologist
Volume	32
Issue number	5
Early online date	14 Nov 2017
DOIs	https://doi.org/10.1080/13854046.2017.1403652
Publication status	Published - 2018

Bibliographical note

Acknowledgments: The authors thank the Swiss National Science Foundation (SNSF, Switzerland) and the Agence Nationale de la Recherche (ANR, France) for their support.

Keywords

Prospective memory
Time checking
22q11.2 deletion syndrome

Access to Document

10.1080/13854046.2017.1403652Licence: Unspecified

Accepted Manuscript
This is an Accepted Manuscript of an article published by Taylor & Francis in The Clinical Neuropsychologist on 14 Nov 2017, available online: http://www.tandfonline.com/10.1080/13854046.2017.1403652
Accepted author manuscript, 657 KBLicence: Unspecified
Figure 3Accepted author manuscript, 475 KBLicence: Unspecified
Figure12Accepted author manuscript, 310 KBLicence: Unspecified

Cite this

@article{a7d6485bbf094e228b7f398fc0d443ac,

title = "Time-based prospective memory in children and adolescents with 22q11.2 deletion syndrome",

abstract = "Objective: 22q11.2 deletion syndrome, also known as velo-cardio-facial syndrome (VCFS) is a genetic disorder caused by a microdeletion on chromosome 22q11.2 and characterized by marked impairment in visual attention and executive function. The present study examined if this cognitive deficit extends to prospective memory (the type of memory involved in remembering to perform actions in the future).Method: 20 participants with 22q11.2DS aged between 6 and 14 were included in the study as well as 22 typically developing individuals (TDC) aged 6 to 12. To measure prospective memory, participants were asked to play a driving game (the Dresden Cruiser, Voigt et al., 2014). This time-based prospective memory task required children to remember to refuel their car when the fuel level was low by pressing a refuel button while driving.Results and Discussion: Participants with 22q11.2DS remembered less often to refuel the car. Furthermore, participants with 22q11.2DS checked the fuel gauge significantly less often than the controls.Conclusions: Participants with 22q11.2DS therefore demonstrate difficulties completing a time-based prospective memory task. This can be explained by a generally less frequent time checking behaviour in comparison to TDC.",

keywords = "Prospective memory, Time checking, 22q11.2 deletion syndrome",

author = "C{\'e}line Souchay and Lydia Dubourg and Nicola Ballhausen and Maude Schneider and Charline Cerf and Katharina Schnitzspahn and Laurence Faivre and Matthias Kliegel and Stephan Eliez",

note = "Acknowledgments: The authors thank the Swiss National Science Foundation (SNSF, Switzerland) and the Agence Nationale de la Recherche (ANR, France) for their support.",

year = "2018",

doi = "10.1080/13854046.2017.1403652",

language = "English",

volume = "32",

pages = "981--992",

journal = "Clinical Neuropsychologist",

issn = "1385-4046",

publisher = "Taylor and Francis Ltd.",

number = "5",

}

TY - JOUR

T1 - Time-based prospective memory in children and adolescents with 22q11.2 deletion syndrome

AU - Souchay, Céline

AU - Dubourg, Lydia

AU - Ballhausen, Nicola

AU - Schneider, Maude

AU - Cerf, Charline

AU - Schnitzspahn, Katharina

AU - Faivre, Laurence

AU - Kliegel, Matthias

AU - Eliez, Stephan

N1 - Acknowledgments: The authors thank the Swiss National Science Foundation (SNSF, Switzerland) and the Agence Nationale de la Recherche (ANR, France) for their support.

PY - 2018

Y1 - 2018

N2 - Objective: 22q11.2 deletion syndrome, also known as velo-cardio-facial syndrome (VCFS) is a genetic disorder caused by a microdeletion on chromosome 22q11.2 and characterized by marked impairment in visual attention and executive function. The present study examined if this cognitive deficit extends to prospective memory (the type of memory involved in remembering to perform actions in the future).Method: 20 participants with 22q11.2DS aged between 6 and 14 were included in the study as well as 22 typically developing individuals (TDC) aged 6 to 12. To measure prospective memory, participants were asked to play a driving game (the Dresden Cruiser, Voigt et al., 2014). This time-based prospective memory task required children to remember to refuel their car when the fuel level was low by pressing a refuel button while driving.Results and Discussion: Participants with 22q11.2DS remembered less often to refuel the car. Furthermore, participants with 22q11.2DS checked the fuel gauge significantly less often than the controls.Conclusions: Participants with 22q11.2DS therefore demonstrate difficulties completing a time-based prospective memory task. This can be explained by a generally less frequent time checking behaviour in comparison to TDC.

AB - Objective: 22q11.2 deletion syndrome, also known as velo-cardio-facial syndrome (VCFS) is a genetic disorder caused by a microdeletion on chromosome 22q11.2 and characterized by marked impairment in visual attention and executive function. The present study examined if this cognitive deficit extends to prospective memory (the type of memory involved in remembering to perform actions in the future).Method: 20 participants with 22q11.2DS aged between 6 and 14 were included in the study as well as 22 typically developing individuals (TDC) aged 6 to 12. To measure prospective memory, participants were asked to play a driving game (the Dresden Cruiser, Voigt et al., 2014). This time-based prospective memory task required children to remember to refuel their car when the fuel level was low by pressing a refuel button while driving.Results and Discussion: Participants with 22q11.2DS remembered less often to refuel the car. Furthermore, participants with 22q11.2DS checked the fuel gauge significantly less often than the controls.Conclusions: Participants with 22q11.2DS therefore demonstrate difficulties completing a time-based prospective memory task. This can be explained by a generally less frequent time checking behaviour in comparison to TDC.

KW - Prospective memory

KW - Time checking

KW - 22q11.2 deletion syndrome

U2 - 10.1080/13854046.2017.1403652

DO - 10.1080/13854046.2017.1403652

M3 - Article

SN - 1385-4046

VL - 32

SP - 981

EP - 992

JO - Clinical Neuropsychologist

JF - Clinical Neuropsychologist

IS - 5

ER -

Time-based prospective memory in children and adolescents with 22q11.2 deletion syndrome

Abstract

Bibliographical note

Keywords

Access to Document

Fingerprint

Cite this