Towards selective breeding of Atlantic salmon for sea louse resistance: approaches to identify trait markers

Catherine Sue Jones, A. E. Lockyer, Eric Verspoor, Christopher John Secombes, Leslie Robert Noble

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Several species of sea lice, in particular Lepeophtheirus salmonis (Kroyer), affect the welfare and condition of farmed salmon, with an estimated annual cost to the Scottish industry of 15-30 million. In Atlantic salmon, some stocks show resistance to L salmonis. Such natural resistance could be utilized for stock improvement using molecular genetic technologies. The development of molecular markers linked to resistance genes, allowing the identification of resistant fish, could increase the efficacy of selective breeding programmes. Various approaches to achieve this goal are described. One way to identify genes conferring resistance is to develop screens for salmon genes that are activated upon louse infection. One such screen-differential display-requires no previous knowledge of gene sequences, involves no preconceptions about which gene families are involved and can therefore identify novel genes. Preliminary results of comparative gene expression in sea-louse-challenged and control fish illustrate the application of differential display. (C) 2002 Society of Chemical Industry.

Original languageEnglish
Pages (from-to)559-568
Number of pages9
JournalPest Management Science
Volume58
DOIs
Publication statusPublished - 2002

Keywords

  • Atlantic salmon
  • Salmo salar
  • sea lice
  • Lepeophtheiries sahnonis
  • QTLs
  • Quantitative Trait Loci
  • comparative gene expression
  • MAJOR HISTOCOMPATIBILITY COMPLEX
  • TROUT ONCORHYNCHUS-MYKISS
  • BULKED SEGREGANT ANALYSIS
  • MHC CLASS-II
  • UPPER TEMPERATURE TOLERANCE
  • ARBITRARILY PRIMED PCR
  • IHN VIRUS-RESISTANCE
  • LEPEOPHTHEIRUS-SALMONIS
  • RAINBOW-TROUT
  • SALAR L

Cite this

Towards selective breeding of Atlantic salmon for sea louse resistance: approaches to identify trait markers. / Jones, Catherine Sue; Lockyer, A. E.; Verspoor, Eric; Secombes, Christopher John; Noble, Leslie Robert.

In: Pest Management Science, Vol. 58, 2002, p. 559-568.

Research output: Contribution to journalArticle

Jones, Catherine Sue ; Lockyer, A. E. ; Verspoor, Eric ; Secombes, Christopher John ; Noble, Leslie Robert. / Towards selective breeding of Atlantic salmon for sea louse resistance: approaches to identify trait markers. In: Pest Management Science. 2002 ; Vol. 58. pp. 559-568.
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