Uncertain role of spirometry in managing childhood asthma in the UK 2019

Stephen W. Turner (Corresponding Author)

Research output: Contribution to journalLetter

Abstract

Asthma guidelines recommend that spirometry should be used for monitoring the condition in children. Surprisingly there is no link between rising or falling spirometry and treatment change. One guideline recommends that treatment might be increased if the per cent forced expiratory volume in 1 s (FEV1) is <80% or <60% of predicted.1 However, lung function is usually within the normal range in children2 with asthma, so these cut-offs are not helpful. Recently published data3 provide evidence of proof-of-concept and inform sample size calculation for a ‘spirometry trial’.
Original languageEnglish
JournalArchives of Disease in Childhood
Early online date3 Jul 2019
DOIs
Publication statusE-pub ahead of print - 3 Jul 2019

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Spirometry
Asthma
Guidelines
Forced Expiratory Volume
Sample Size
Reference Values
Lung
Therapeutics

Cite this

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abstract = "Asthma guidelines recommend that spirometry should be used for monitoring the condition in children. Surprisingly there is no link between rising or falling spirometry and treatment change. One guideline recommends that treatment might be increased if the per cent forced expiratory volume in 1 s (FEV1) is <80{\%} or <60{\%} of predicted.1 However, lung function is usually within the normal range in children2 with asthma, so these cut-offs are not helpful. Recently published data3 provide evidence of proof-of-concept and inform sample size calculation for a ‘spirometry trial’.",
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AB - Asthma guidelines recommend that spirometry should be used for monitoring the condition in children. Surprisingly there is no link between rising or falling spirometry and treatment change. One guideline recommends that treatment might be increased if the per cent forced expiratory volume in 1 s (FEV1) is <80% or <60% of predicted.1 However, lung function is usually within the normal range in children2 with asthma, so these cut-offs are not helpful. Recently published data3 provide evidence of proof-of-concept and inform sample size calculation for a ‘spirometry trial’.

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