Unexplained infertility

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Expectant management has a key role in the management of unexplained infertility. The decision to treat couples with unexplained infertility should take into account their chances of spontaneous conception, which is affected by female age, duration of infertility and occurrence of a previous pregnancy. The rationale for the use of oral clomifene citrate in unexplained infertility is the belief that it corrects subtle ovulatory dysfunction and encourages the release of more than one oocyte. Clomifene is inexpensive, non-invasive and requires little clinical monitoring, but it can cause multiple pregnancies, including high-order multiples. Intrauterine insemination (IUI) has been used widely for the treatment of unexplained infertility. It is thought to enhance the chance of pregnancy by increasing the number of motile spermatozoa within the uterus, bringing them in close proximity to the oocyte. Although more effective than IUI, superovulation (SO) along with IUI is associated with high rates of multiple births.
Original languageEnglish
Title of host publicationManagement of Infertility
Subtitle of host publicationfor the MRCOG and Beyond
Editors Siladitya Bhattacharya, Mark Hamilton
PublisherCambridge University Press
Pages77-84
Number of pages8
EditionThird Edition
ISBN (Electronic)9781107445178
ISBN (Print)9781107678576
DOIs
Publication statusPublished - Jun 2014

Fingerprint

Infertility
Insemination
Clomiphene
Oocytes
Superovulation
Multiple Birth Offspring
Pregnancy
Multiple Pregnancy
Citric Acid
Uterus
Spermatozoa
Therapeutics

Keywords

  • Medicine
  • Obstetrics and gynecology
  • Reproductive medicine

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Bhattacharya, S. (2014). Unexplained infertility. In S. Bhattacharya, & M. Hamilton (Eds.), Management of Infertility: for the MRCOG and Beyond (Third Edition ed., pp. 77-84). Cambridge University Press. https://doi.org/10.1017/CBO9781107445178.009

Unexplained infertility. / Bhattacharya, Siladitya.

Management of Infertility: for the MRCOG and Beyond. ed. / Siladitya Bhattacharya; Mark Hamilton. Third Edition. ed. Cambridge University Press, 2014. p. 77-84.

Research output: Chapter in Book/Report/Conference proceedingChapter

Bhattacharya, S 2014, Unexplained infertility. in S Bhattacharya & M Hamilton (eds), Management of Infertility: for the MRCOG and Beyond. Third Edition edn, Cambridge University Press, pp. 77-84. https://doi.org/10.1017/CBO9781107445178.009
Bhattacharya S. Unexplained infertility. In Bhattacharya S, Hamilton M, editors, Management of Infertility: for the MRCOG and Beyond. Third Edition ed. Cambridge University Press. 2014. p. 77-84 https://doi.org/10.1017/CBO9781107445178.009
Bhattacharya, Siladitya. / Unexplained infertility. Management of Infertility: for the MRCOG and Beyond. editor / Siladitya Bhattacharya ; Mark Hamilton. Third Edition. ed. Cambridge University Press, 2014. pp. 77-84
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