Use of time to pregnancy in environmental epidemiology and surveillance

Mike Joffe, Shantini Paranjothy, Hilary Fielder, Ronan Lyons, Stephen R Palmer

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)


Background Potential sources of environmental pollution, such as incinerators or landfill sites, can adversely affect reproduction and/or development. Time to pregnancy (TTP) is a validated measure of biological fertility that can be studied with relatively small populations. Methods Pregnant local residents living within 3 km of a landfill site (?exposed? group, n = 200) or elsewhere in the Rhondda valleys (?unexposed? group, n = 400) were interviewed by health visitors or midwives. The response rate was 83%. Results No difference was found in the TTP distributions between the exposed and unexposed groups. Relationships of TTP with covariates were consistent with the literature. Conclusions In a context of public and scientific concern about possible reproductive toxicity, an interview study of TTP was highly acceptable to local women. A large enough sample to generate stable TTP distributions was readily achieved.
Original languageEnglish
Pages (from-to)178-185
Number of pages8
JournalJournal of Public Health
Issue number2
Publication statusPublished - 2008


  • Environmental epidemiology ; Fertility ; Fecundity ; Landfill ; Reproduction ; Time to pregnancy


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