Using postal randomization to replace telephone randomization had no significant effect on recruitment of patients

S. D. Brealey, C. Atwell, S. Bryan, S. Coulton, H. Cox, B. Cross, F. Fylan, A. M. Garratt, Fiona Jane Gilbert, Maureen Grace Charles Gillan, M. Hendry, K. Hood, H. Houston, David King, Veronica Morton, Jo Orchard, Michael Robling, I. T. Russell, D. J. Torgerson, Valerie Wadsworth & 1 others C. Wilkinson

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Objective: To test the effect of postal randomization on recruitment of patients into a randomized trial in primary care.

Study Design and Setting: General practices used a telephone service to randomize patients in our trial. Delays in the start of recruitment at some sites led us to modify the randomization procedure. When new practices took part patients completed and posted baseline materials to the Trial Secretary in York who performed the randomization and informed those concerned of the allocation.

Results: Of the 647 practices who were invited to take part, 130 (45%) of 288 agreed to participate using telephone randomization and 155 (43%) of 359 using the postal method. These practices recruited 553 patients from November 2002 to October 2004 across 11 sites in the United Kingdom. The postal method reduced the number of patients recruited by a factor of 0.86 (95% confidence interval = 0.62-1.20), or 14%. The number of general practitioners working in a practice significantly increased patient recruitment by a factor of 1.12 (1.05-1.20), whereas practice distance from hospital significantly decreased recruitment by a factor of 0.98 (0.97-0.99).

Conclusion: Postal randomization had no significant effect on recruitment of patients into our trial. (C) 2007 Elsevier Inc. All rights reserved.

Original languageEnglish
Pages (from-to)1046-1051
Number of pages6
JournalJournal of Clinical Epidemiology
Volume60
Issue number10
DOIs
Publication statusPublished - Oct 2007

Keywords

  • patient recruitment
  • family practice
  • randomized controlled trial
  • magnetic resonance imaging
  • internal derangement of the knee
  • negative binomial regression
  • primary-care
  • clinical-trials
  • general-practice
  • knee
  • arthroscopy

Cite this

Using postal randomization to replace telephone randomization had no significant effect on recruitment of patients. / Brealey, S. D.; Atwell, C.; Bryan, S.; Coulton, S.; Cox, H.; Cross, B.; Fylan, F.; Garratt, A. M.; Gilbert, Fiona Jane; Gillan, Maureen Grace Charles; Hendry, M.; Hood, K.; Houston, H.; King, David; Morton, Veronica; Orchard, Jo; Robling, Michael; Russell, I. T.; Torgerson, D. J.; Wadsworth, Valerie; Wilkinson, C.

In: Journal of Clinical Epidemiology, Vol. 60, No. 10, 10.2007, p. 1046-1051.

Research output: Contribution to journalArticle

Brealey, SD, Atwell, C, Bryan, S, Coulton, S, Cox, H, Cross, B, Fylan, F, Garratt, AM, Gilbert, FJ, Gillan, MGC, Hendry, M, Hood, K, Houston, H, King, D, Morton, V, Orchard, J, Robling, M, Russell, IT, Torgerson, DJ, Wadsworth, V & Wilkinson, C 2007, 'Using postal randomization to replace telephone randomization had no significant effect on recruitment of patients', Journal of Clinical Epidemiology, vol. 60, no. 10, pp. 1046-1051. https://doi.org/10.1016/j.jclinepi.2007.04.003
Brealey, S. D. ; Atwell, C. ; Bryan, S. ; Coulton, S. ; Cox, H. ; Cross, B. ; Fylan, F. ; Garratt, A. M. ; Gilbert, Fiona Jane ; Gillan, Maureen Grace Charles ; Hendry, M. ; Hood, K. ; Houston, H. ; King, David ; Morton, Veronica ; Orchard, Jo ; Robling, Michael ; Russell, I. T. ; Torgerson, D. J. ; Wadsworth, Valerie ; Wilkinson, C. / Using postal randomization to replace telephone randomization had no significant effect on recruitment of patients. In: Journal of Clinical Epidemiology. 2007 ; Vol. 60, No. 10. pp. 1046-1051.
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abstract = "Objective: To test the effect of postal randomization on recruitment of patients into a randomized trial in primary care.Study Design and Setting: General practices used a telephone service to randomize patients in our trial. Delays in the start of recruitment at some sites led us to modify the randomization procedure. When new practices took part patients completed and posted baseline materials to the Trial Secretary in York who performed the randomization and informed those concerned of the allocation.Results: Of the 647 practices who were invited to take part, 130 (45{\%}) of 288 agreed to participate using telephone randomization and 155 (43{\%}) of 359 using the postal method. These practices recruited 553 patients from November 2002 to October 2004 across 11 sites in the United Kingdom. The postal method reduced the number of patients recruited by a factor of 0.86 (95{\%} confidence interval = 0.62-1.20), or 14{\%}. The number of general practitioners working in a practice significantly increased patient recruitment by a factor of 1.12 (1.05-1.20), whereas practice distance from hospital significantly decreased recruitment by a factor of 0.98 (0.97-0.99).Conclusion: Postal randomization had no significant effect on recruitment of patients into our trial. (C) 2007 Elsevier Inc. All rights reserved.",
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AU - Atwell, C.

AU - Bryan, S.

AU - Coulton, S.

AU - Cox, H.

AU - Cross, B.

AU - Fylan, F.

AU - Garratt, A. M.

AU - Gilbert, Fiona Jane

AU - Gillan, Maureen Grace Charles

AU - Hendry, M.

AU - Hood, K.

AU - Houston, H.

AU - King, David

AU - Morton, Veronica

AU - Orchard, Jo

AU - Robling, Michael

AU - Russell, I. T.

AU - Torgerson, D. J.

AU - Wadsworth, Valerie

AU - Wilkinson, C.

PY - 2007/10

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N2 - Objective: To test the effect of postal randomization on recruitment of patients into a randomized trial in primary care.Study Design and Setting: General practices used a telephone service to randomize patients in our trial. Delays in the start of recruitment at some sites led us to modify the randomization procedure. When new practices took part patients completed and posted baseline materials to the Trial Secretary in York who performed the randomization and informed those concerned of the allocation.Results: Of the 647 practices who were invited to take part, 130 (45%) of 288 agreed to participate using telephone randomization and 155 (43%) of 359 using the postal method. These practices recruited 553 patients from November 2002 to October 2004 across 11 sites in the United Kingdom. The postal method reduced the number of patients recruited by a factor of 0.86 (95% confidence interval = 0.62-1.20), or 14%. The number of general practitioners working in a practice significantly increased patient recruitment by a factor of 1.12 (1.05-1.20), whereas practice distance from hospital significantly decreased recruitment by a factor of 0.98 (0.97-0.99).Conclusion: Postal randomization had no significant effect on recruitment of patients into our trial. (C) 2007 Elsevier Inc. All rights reserved.

AB - Objective: To test the effect of postal randomization on recruitment of patients into a randomized trial in primary care.Study Design and Setting: General practices used a telephone service to randomize patients in our trial. Delays in the start of recruitment at some sites led us to modify the randomization procedure. When new practices took part patients completed and posted baseline materials to the Trial Secretary in York who performed the randomization and informed those concerned of the allocation.Results: Of the 647 practices who were invited to take part, 130 (45%) of 288 agreed to participate using telephone randomization and 155 (43%) of 359 using the postal method. These practices recruited 553 patients from November 2002 to October 2004 across 11 sites in the United Kingdom. The postal method reduced the number of patients recruited by a factor of 0.86 (95% confidence interval = 0.62-1.20), or 14%. The number of general practitioners working in a practice significantly increased patient recruitment by a factor of 1.12 (1.05-1.20), whereas practice distance from hospital significantly decreased recruitment by a factor of 0.98 (0.97-0.99).Conclusion: Postal randomization had no significant effect on recruitment of patients into our trial. (C) 2007 Elsevier Inc. All rights reserved.

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KW - general-practice

KW - knee

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