Vaginal metastases from colorectal cancer

Hwei Jene Ng, E H Aly

Research output: Contribution to journalReview article

8 Citations (Scopus)

Abstract

BACKGROUND: Vaginal metastases originating from colorectal carcinoma are very rare. Due to the limited number of reported cases, there is no proposed standard treatment and little is known about its management outcome.

AIM: The aim of this article is to review the available literature to establish the clinical presentation, trends in treatment and prognosis of vaginal metastases from colorectal malignancy.

METHODS: A literature search using keywords used for database search were 'colorectal carcinoma', 'colorectal cancer', 'colon cancer' and 'vaginal metastasis'.

RESULTS: Of the 30 articles identified, 37 reported cases, were accessible for full evaluation. Cases reported originates from various countries and majority presented with vaginal bleeding. Diagnosis was established after histological examination and treatment options consist of surgical resection, radiotherapy or chemotherapy that have been used individually or in combination. Association with disseminated metastatic disease indicates ominous prognosis as seen in 32.4% (n = 12) cases.

CONCLUSION: Vaginal metastasis of colorectal cancer should be included in the differential diagnosis of a vaginal swelling. There is no proposed standard treatment for vaginal metastases but surgical resection is an appropriate approach for local control when no disseminated metastatic disease is documented.

Original languageEnglish
Pages (from-to)1048-1055
Number of pages8
JournalInternational Journal of Surgery
Volume11
Issue number10
Early online date27 Sep 2013
DOIs
Publication statusPublished - Dec 2013

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Colorectal Neoplasms
Neoplasm Metastasis
Colonic Neoplasms
Uterine Hemorrhage
Therapeutics
Differential Diagnosis
Radiotherapy
Databases
Drug Therapy
Neoplasms

Keywords

  • Vaginal metastases
  • Colorectal cancer

Cite this

Vaginal metastases from colorectal cancer. / Ng, Hwei Jene; Aly, E H.

In: International Journal of Surgery , Vol. 11, No. 10, 12.2013, p. 1048-1055.

Research output: Contribution to journalReview article

Ng, Hwei Jene ; Aly, E H. / Vaginal metastases from colorectal cancer. In: International Journal of Surgery . 2013 ; Vol. 11, No. 10. pp. 1048-1055.
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title = "Vaginal metastases from colorectal cancer",
abstract = "BACKGROUND: Vaginal metastases originating from colorectal carcinoma are very rare. Due to the limited number of reported cases, there is no proposed standard treatment and little is known about its management outcome.AIM: The aim of this article is to review the available literature to establish the clinical presentation, trends in treatment and prognosis of vaginal metastases from colorectal malignancy.METHODS: A literature search using keywords used for database search were 'colorectal carcinoma', 'colorectal cancer', 'colon cancer' and 'vaginal metastasis'.RESULTS: Of the 30 articles identified, 37 reported cases, were accessible for full evaluation. Cases reported originates from various countries and majority presented with vaginal bleeding. Diagnosis was established after histological examination and treatment options consist of surgical resection, radiotherapy or chemotherapy that have been used individually or in combination. Association with disseminated metastatic disease indicates ominous prognosis as seen in 32.4{\%} (n = 12) cases.CONCLUSION: Vaginal metastasis of colorectal cancer should be included in the differential diagnosis of a vaginal swelling. There is no proposed standard treatment for vaginal metastases but surgical resection is an appropriate approach for local control when no disseminated metastatic disease is documented.",
keywords = "Vaginal metastases, Colorectal cancer",
author = "Ng, {Hwei Jene} and Aly, {E H}",
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T1 - Vaginal metastases from colorectal cancer

AU - Ng, Hwei Jene

AU - Aly, E H

N1 - Copyright © 2013 Surgical Associates Ltd. Published by Elsevier Ltd. All rights reserved.

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Y1 - 2013/12

N2 - BACKGROUND: Vaginal metastases originating from colorectal carcinoma are very rare. Due to the limited number of reported cases, there is no proposed standard treatment and little is known about its management outcome.AIM: The aim of this article is to review the available literature to establish the clinical presentation, trends in treatment and prognosis of vaginal metastases from colorectal malignancy.METHODS: A literature search using keywords used for database search were 'colorectal carcinoma', 'colorectal cancer', 'colon cancer' and 'vaginal metastasis'.RESULTS: Of the 30 articles identified, 37 reported cases, were accessible for full evaluation. Cases reported originates from various countries and majority presented with vaginal bleeding. Diagnosis was established after histological examination and treatment options consist of surgical resection, radiotherapy or chemotherapy that have been used individually or in combination. Association with disseminated metastatic disease indicates ominous prognosis as seen in 32.4% (n = 12) cases.CONCLUSION: Vaginal metastasis of colorectal cancer should be included in the differential diagnosis of a vaginal swelling. There is no proposed standard treatment for vaginal metastases but surgical resection is an appropriate approach for local control when no disseminated metastatic disease is documented.

AB - BACKGROUND: Vaginal metastases originating from colorectal carcinoma are very rare. Due to the limited number of reported cases, there is no proposed standard treatment and little is known about its management outcome.AIM: The aim of this article is to review the available literature to establish the clinical presentation, trends in treatment and prognosis of vaginal metastases from colorectal malignancy.METHODS: A literature search using keywords used for database search were 'colorectal carcinoma', 'colorectal cancer', 'colon cancer' and 'vaginal metastasis'.RESULTS: Of the 30 articles identified, 37 reported cases, were accessible for full evaluation. Cases reported originates from various countries and majority presented with vaginal bleeding. Diagnosis was established after histological examination and treatment options consist of surgical resection, radiotherapy or chemotherapy that have been used individually or in combination. Association with disseminated metastatic disease indicates ominous prognosis as seen in 32.4% (n = 12) cases.CONCLUSION: Vaginal metastasis of colorectal cancer should be included in the differential diagnosis of a vaginal swelling. There is no proposed standard treatment for vaginal metastases but surgical resection is an appropriate approach for local control when no disseminated metastatic disease is documented.

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KW - Colorectal cancer

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JO - International Journal of Surgery

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SN - 1743-9159

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