Validity of the general practice research database

S. S. Jick, J. A. Kaye, C. Vasilakis-Scaramozza, L. A. Garcia Rodriguez, A. Ruigomez, C. R. Meier, R. Schlienger, Corrinda Black, H. Jick

Research output: Contribution to journalArticle

456 Citations (Scopus)

Abstract

The United Kingdom General Practice Research Database (GPRD) is an office-based, computer-generated, medical resource designed from its inception to be used for epidemiologic research. A distinct version of the GPRD is maintained by the Boston Collaborative Drug Surveillance Program and has been the source of more than 130 scientific articles primarily addressing drug safety issues. We reviewed evidence related to the validity of the GPRD. Specifically, with our extensive experience with this automated database, we evaluated the quality and completeness of the data that it contains.

Original languageEnglish
Pages (from-to)686-689
Number of pages3
JournalPharmacotherapy
Volume23
Issue number5
DOIs
Publication statusPublished - 2003

Keywords

  • NONSTEROIDAL ANTIINFLAMMATORY DRUGS
  • COA REDUCTASE INHIBITORS
  • VENOUS THROMBOEMBOLISM
  • ORAL-CONTRACEPTIVES
  • RUBELLA VACCINE
  • UNITED-KINGDOM
  • BREAST-CANCER
  • RISK
  • PROGESTAGEN
  • TAMOXIFEN

Cite this

Jick, S. S., Kaye, J. A., Vasilakis-Scaramozza, C., Garcia Rodriguez, L. A., Ruigomez, A., Meier, C. R., Schlienger, R., Black, C., & Jick, H. (2003). Validity of the general practice research database. Pharmacotherapy, 23(5), 686-689. https://doi.org/10.1592/phco.23.5.686.32205