Ventricular arrhythmias and changes in heart rate preceding ventricular tachycardia in patients with an implantable cardioverter defibrillator

Claudia Lerma, Niels Wessel, Alexander Schirdewan, Juergen Kurths, Leon Glass

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

The objective was to determine the characteristics of heart rate variability and ventricular arrhythmias prior to the onset of ventricular tachycardia (VT) in patients with an implantable cardioverter defibrillator (ICD). Sixty-eight beat-to-beat time series from 13 patients with an ICD were analyzed to quantify heart rate variability and ventricular arrhythmias. The episodes of VT were classified in one of two groups depending on whether the sinus rate in the 1 min preceding the VT was greater or less than 90 beats per minute. In a subset of patients, increased heart rate and reduced heart rate variability was often observed up to 20 min prior to the VT. There was a non-significant trend to higher incidence of premature ventricular complexes (PVCs) before VT compared to control recordings. The patterns of the ventricular arrhythmias were highly heterogeneous among different patients and even within the same patient. Analysis of the changes of heart rate and heart rate variability may have predictive value about the onset of VT in selected patients. The patterns of ventricular arrhythmia could not be used to predict onset of VT in this group of patients.

Original languageEnglish
Pages (from-to)715-727
Number of pages13
JournalMedical & biological engineering & computing
Volume46
Issue number7
Early online date15 Mar 2008
DOIs
Publication statusPublished - Jul 2008

Keywords

  • ventricular arrhythmias
  • heart rate variability
  • implantable cardioverter defibrillators
  • non-linear methods
  • ventricular tachycardia

Cite this

Ventricular arrhythmias and changes in heart rate preceding ventricular tachycardia in patients with an implantable cardioverter defibrillator. / Lerma, Claudia; Wessel, Niels; Schirdewan, Alexander; Kurths, Juergen; Glass, Leon.

In: Medical & biological engineering & computing, Vol. 46, No. 7, 07.2008, p. 715-727.

Research output: Contribution to journalArticle

Lerma, Claudia ; Wessel, Niels ; Schirdewan, Alexander ; Kurths, Juergen ; Glass, Leon. / Ventricular arrhythmias and changes in heart rate preceding ventricular tachycardia in patients with an implantable cardioverter defibrillator. In: Medical & biological engineering & computing. 2008 ; Vol. 46, No. 7. pp. 715-727.
@article{3d2c4aa2e34841068636964bd669a578,
title = "Ventricular arrhythmias and changes in heart rate preceding ventricular tachycardia in patients with an implantable cardioverter defibrillator",
abstract = "The objective was to determine the characteristics of heart rate variability and ventricular arrhythmias prior to the onset of ventricular tachycardia (VT) in patients with an implantable cardioverter defibrillator (ICD). Sixty-eight beat-to-beat time series from 13 patients with an ICD were analyzed to quantify heart rate variability and ventricular arrhythmias. The episodes of VT were classified in one of two groups depending on whether the sinus rate in the 1 min preceding the VT was greater or less than 90 beats per minute. In a subset of patients, increased heart rate and reduced heart rate variability was often observed up to 20 min prior to the VT. There was a non-significant trend to higher incidence of premature ventricular complexes (PVCs) before VT compared to control recordings. The patterns of the ventricular arrhythmias were highly heterogeneous among different patients and even within the same patient. Analysis of the changes of heart rate and heart rate variability may have predictive value about the onset of VT in selected patients. The patterns of ventricular arrhythmia could not be used to predict onset of VT in this group of patients.",
keywords = "ventricular arrhythmias, heart rate variability, implantable cardioverter defibrillators, non-linear methods, ventricular tachycardia",
author = "Claudia Lerma and Niels Wessel and Alexander Schirdewan and Juergen Kurths and Leon Glass",
year = "2008",
month = "7",
doi = "10.1007/s11517-008-0326-y",
language = "English",
volume = "46",
pages = "715--727",
journal = "Medical & biological engineering & computing",
issn = "0140-0118",
publisher = "Springer Verlag",
number = "7",

}

TY - JOUR

T1 - Ventricular arrhythmias and changes in heart rate preceding ventricular tachycardia in patients with an implantable cardioverter defibrillator

AU - Lerma, Claudia

AU - Wessel, Niels

AU - Schirdewan, Alexander

AU - Kurths, Juergen

AU - Glass, Leon

PY - 2008/7

Y1 - 2008/7

N2 - The objective was to determine the characteristics of heart rate variability and ventricular arrhythmias prior to the onset of ventricular tachycardia (VT) in patients with an implantable cardioverter defibrillator (ICD). Sixty-eight beat-to-beat time series from 13 patients with an ICD were analyzed to quantify heart rate variability and ventricular arrhythmias. The episodes of VT were classified in one of two groups depending on whether the sinus rate in the 1 min preceding the VT was greater or less than 90 beats per minute. In a subset of patients, increased heart rate and reduced heart rate variability was often observed up to 20 min prior to the VT. There was a non-significant trend to higher incidence of premature ventricular complexes (PVCs) before VT compared to control recordings. The patterns of the ventricular arrhythmias were highly heterogeneous among different patients and even within the same patient. Analysis of the changes of heart rate and heart rate variability may have predictive value about the onset of VT in selected patients. The patterns of ventricular arrhythmia could not be used to predict onset of VT in this group of patients.

AB - The objective was to determine the characteristics of heart rate variability and ventricular arrhythmias prior to the onset of ventricular tachycardia (VT) in patients with an implantable cardioverter defibrillator (ICD). Sixty-eight beat-to-beat time series from 13 patients with an ICD were analyzed to quantify heart rate variability and ventricular arrhythmias. The episodes of VT were classified in one of two groups depending on whether the sinus rate in the 1 min preceding the VT was greater or less than 90 beats per minute. In a subset of patients, increased heart rate and reduced heart rate variability was often observed up to 20 min prior to the VT. There was a non-significant trend to higher incidence of premature ventricular complexes (PVCs) before VT compared to control recordings. The patterns of the ventricular arrhythmias were highly heterogeneous among different patients and even within the same patient. Analysis of the changes of heart rate and heart rate variability may have predictive value about the onset of VT in selected patients. The patterns of ventricular arrhythmia could not be used to predict onset of VT in this group of patients.

KW - ventricular arrhythmias

KW - heart rate variability

KW - implantable cardioverter defibrillators

KW - non-linear methods

KW - ventricular tachycardia

U2 - 10.1007/s11517-008-0326-y

DO - 10.1007/s11517-008-0326-y

M3 - Article

VL - 46

SP - 715

EP - 727

JO - Medical & biological engineering & computing

JF - Medical & biological engineering & computing

SN - 0140-0118

IS - 7

ER -