This review outlines what we know about cytokines and their evolution within vertebrates. It is focused on the interleukins, as key cytokines involved in the regulation of adaptive immunity, as well as the TNF family of cytokines. The genes that are known, and their function, are outlined as far as possible, and potential modes of evolution within cytokine gene families is discussed.
|Title of host publication||The Evolution of the Immune System|
|Subtitle of host publication||Conservation and Diversification|
|Number of pages||64|
|Publication status||Published - 20 May 2016|
- Tumor necrosis factors
ASJC Scopus subject areas
- Immunology and Microbiology(all)