Vibrational structure of the polyunsaturated fatty acids eicosapentaenoic acid and arachidonic acid studied by infrared spectroscopy

Johannes Kiefer, Kristina Noack, Juergen Bartelmess, Chris Walter, Heike Doernenburg, Alfred Leipertz

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Abstract

The spectroscopic discrimination of the two structurally similar polyunsaturated C-20 fatty acids (PUFAs) 5,8,11,14,17-eicosapentaenoic acid and 5,8,11,14-eicosatetraenoic acid (arachidonic acid) is shown. For this purpose their vibrational structures are studied by means of attenuated total reflection (ATR) Fourier-transform infrared (FT-IR) spectroscopy. The fingerprint regions of the recorded spectra are found to be almost identical, while the C-H stretching mode regions around 3000 cm(-1) show such significant differences as results of electronic and molecular structure alterations based on the different degree of Saturation that both fatty acids can be clearly distinguished from each other. (C) 2009 Elsevier B.V. All rights reserved.
Original languageEnglish
Pages (from-to)121-124
Number of pages4
JournalJournal of Molecular Structure
Volume965
Issue number1-3
Early online date26 Nov 2009
DOIs
Publication statusPublished - 25 Feb 2010

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Keywords

  • Vibrational structure
  • Polyunsaturated fatty acid
  • Eicosapentaenoic acid
  • Eicosatetraenoic acid
  • Arachidonic acid
  • Infrared spectroscopy

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