What is the recall rate of breast MRI when used for screening asymptomatic women at high risk?

R. M. Warren, L. J. Pointon, R. Caines, Fiona Jane Gilbert, UK MRI breast screening study

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Breast screening acceptability is dependent on sensitivity and recall rate. We aimed to establish the recall rate for MRI and mammography, separately and together, when screening a cohort of women at high genetic risk. Women aged 35-49 years in the MARIBS study form the cohort. We analysed the recall rate, the number of extra tests and their effectiveness. Wilcoxon Rank test was used to estimate the effect of age and logistic regression with robust variance the effect of mammographic density on recall rates.

The first 726 screening studies took place in 415 women. Following 86 of these recall occurred, comprising 140 additional investigations. 28 of the cases were resolved without further MRI, and 18 women had more than 2 additional tests. Neither age nor mammographic density was associated with recall. MRI had a recall of rate of 10.19%, and mammography 4.00%. The two techniques largely recalled different cases and 10 cases only (11.62% of those recalled) were abnormal by both tests. The two together had a recall rate of 11.85%. Recall rates varied widely between centres of the study.

Breast MRI in asymptomatic high-risk women age 35-49 years largely recalls different women from mammography. The combined figure of approximately 12% may be acceptable for screening and will be useful for planning similar studies. (C) 2002 Elsevier Science Inc. All rights reserved.

Original languageEnglish
Pages (from-to)557-565
Number of pages8
JournalMagnetic Resonance Imaging
Volume20
Publication statusPublished - 2002

Keywords

  • breast cancer
  • screening
  • magnetic resonance imaging
  • high-risk
  • family history
  • breast MR
  • CONTRAST-MEDIUM ENHANCEMENT
  • FAMILY HISTORY
  • GENETIC RISK
  • NATIONAL MULTICENTER
  • CANCER
  • MAMMOGRAPHY
  • DENSITY
  • AGE
  • SENSITIVITY
  • PROTOCOL

Cite this

Warren, R. M., Pointon, L. J., Caines, R., Gilbert, F. J., & UK MRI breast screening study (2002). What is the recall rate of breast MRI when used for screening asymptomatic women at high risk? Magnetic Resonance Imaging, 20, 557-565.

What is the recall rate of breast MRI when used for screening asymptomatic women at high risk? / Warren, R. M.; Pointon, L. J.; Caines, R.; Gilbert, Fiona Jane; UK MRI breast screening study.

In: Magnetic Resonance Imaging, Vol. 20, 2002, p. 557-565.

Research output: Contribution to journalArticle

Warren, RM, Pointon, LJ, Caines, R, Gilbert, FJ & UK MRI breast screening study 2002, 'What is the recall rate of breast MRI when used for screening asymptomatic women at high risk?', Magnetic Resonance Imaging, vol. 20, pp. 557-565.
Warren RM, Pointon LJ, Caines R, Gilbert FJ, UK MRI breast screening study. What is the recall rate of breast MRI when used for screening asymptomatic women at high risk? Magnetic Resonance Imaging. 2002;20:557-565.
Warren, R. M. ; Pointon, L. J. ; Caines, R. ; Gilbert, Fiona Jane ; UK MRI breast screening study. / What is the recall rate of breast MRI when used for screening asymptomatic women at high risk?. In: Magnetic Resonance Imaging. 2002 ; Vol. 20. pp. 557-565.
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