TY - JOUR
T1 - Zinc deficiency negatively affects alkaline phosphatase and the concentration of Ca, Mg and P in rats
AU - Cho, Young-Eun
AU - Lomeda, Ria-Ann R
AU - Ryu, Sang-Hoon
AU - Sohn, Ho-Yong
AU - Shin, Hong-In
AU - Beattie, John H
AU - Kwun, In-Sook
PY - 2007
Y1 - 2007
N2 - Zn is an essential nutrient that is required in humans and animals for many physiological functions, including immune and antioxidant function, growth, and reproduction. The present study evaluated whether Zn deficiency would negatively affect bone-related enzyme, ALP, and other bone-related minerals (Ca, P and Mg) in rats. Thirty Sprague Dawley rats were assigned to one of the three different Zn dietary groups, such as Zn adequate (ZA, 35 mg/kg), pair fed (PF, 35 mg/kg), Zn deficient (ZD, 1 mg/kg) diet, and fed for 10 weeks. Food intake and body weight were measured daily and weekly, respectively. ALP was measured by spectrophotometry and mineral contents were measured by inductively coupled plasma-mass spectrophotometer (ICP-MS). Zn deficient rats showed decreased food intake and body weight compared with Zn adequate rats (p
AB - Zn is an essential nutrient that is required in humans and animals for many physiological functions, including immune and antioxidant function, growth, and reproduction. The present study evaluated whether Zn deficiency would negatively affect bone-related enzyme, ALP, and other bone-related minerals (Ca, P and Mg) in rats. Thirty Sprague Dawley rats were assigned to one of the three different Zn dietary groups, such as Zn adequate (ZA, 35 mg/kg), pair fed (PF, 35 mg/kg), Zn deficient (ZD, 1 mg/kg) diet, and fed for 10 weeks. Food intake and body weight were measured daily and weekly, respectively. ALP was measured by spectrophotometry and mineral contents were measured by inductively coupled plasma-mass spectrophotometer (ICP-MS). Zn deficient rats showed decreased food intake and body weight compared with Zn adequate rats (p
KW - zinc
KW - alkaline phosphatase
KW - bone-related minerals (Ca, P, Mg)
KW - rats
U2 - 10.4162/nrp.2007.1.2.113
DO - 10.4162/nrp.2007.1.2.113
M3 - Article
C2 - 20535396
SN - 2005-6168
VL - 1
SP - 113
EP - 119
JO - Nutrition Research and Practice
JF - Nutrition Research and Practice
IS - 2
ER -