Zinc deficiency negatively affects alkaline phosphatase and the concentration of Ca, Mg and P in rats

Young-Eun Cho, Ria-Ann R Lomeda, Sang-Hoon Ryu, Ho-Yong Sohn, Hong-In Shin, John H Beattie, In-Sook Kwun

    Research output: Contribution to journalArticle

    Abstract

    Zn is an essential nutrient that is required in humans and animals for many physiological functions, including immune and antioxidant function, growth, and reproduction. The present study evaluated whether Zn deficiency would negatively affect bone-related enzyme, ALP, and other bone-related minerals (Ca, P and Mg) in rats. Thirty Sprague Dawley rats were assigned to one of the three different Zn dietary groups, such as Zn adequate (ZA, 35 mg/kg), pair fed (PF, 35 mg/kg), Zn deficient (ZD, 1 mg/kg) diet, and fed for 10 weeks. Food intake and body weight were measured daily and weekly, respectively. ALP was measured by spectrophotometry and mineral contents were measured by inductively coupled plasma-mass spectrophotometer (ICP-MS). Zn deficient rats showed decreased food intake and body weight compared with Zn adequate rats (p
    Original languageEnglish
    Pages (from-to)113-119
    Number of pages7
    JournalNutrition Research and Practice
    Volume1
    Issue number2
    DOIs
    Publication statusPublished - 2007

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    Alkaline Phosphatase
    alkaline phosphatase
    Zinc
    zinc
    Minerals
    rats
    Eating
    Body Weight
    Bone and Bones
    food intake
    Spectrophotometry
    bones
    Reproduction
    body weight
    Sprague Dawley Rats
    spectrophotometers
    Antioxidants
    Diet
    mineral content
    spectroscopy

    Keywords

    • zinc
    • alkaline phosphatase
    • bone-related minerals (Ca, P, Mg)
    • rats

    Cite this

    Zinc deficiency negatively affects alkaline phosphatase and the concentration of Ca, Mg and P in rats. / Cho, Young-Eun; Lomeda, Ria-Ann R; Ryu, Sang-Hoon; Sohn, Ho-Yong; Shin, Hong-In; Beattie, John H; Kwun, In-Sook.

    In: Nutrition Research and Practice, Vol. 1, No. 2, 2007, p. 113-119.

    Research output: Contribution to journalArticle

    Cho, Young-Eun ; Lomeda, Ria-Ann R ; Ryu, Sang-Hoon ; Sohn, Ho-Yong ; Shin, Hong-In ; Beattie, John H ; Kwun, In-Sook. / Zinc deficiency negatively affects alkaline phosphatase and the concentration of Ca, Mg and P in rats. In: Nutrition Research and Practice. 2007 ; Vol. 1, No. 2. pp. 113-119.
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