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Author

  • Leslie Samuel
2011

Complete response rates of rectal cancer to neo-adjuvant chemo-radiotherapy: the North East of Scotland experience

Stevenson, L., Nicol, L., Macdonald, G., Samuel, L., Murray, G., Yule, S. & Aly, E., Sep 2011, In : Colorectal Disease. 13, s6, p. 24 1 p., LTP69.

Research output: Contribution to journalArticle

2017

Preoperative chemoradiation with capecitabine, irinotecan and cetuximab in rectal cancer: significance of pre-treatment and post-resection RAS mutations

Gollins, S., West, N., Sebag-Montefiore, D., Myint, A. S., Saunders, M., Susnerwala, S., Quirke, P., Essapen, S., Samuel, L., Sizer, B., Worlding, J., Southward, K., Hemmings, G., Tinkler-Hundal, E., Taylor, M., Bottomley, D., Chambers, P., Lawrie, E., Lopes, A. & Beare, S., 24 Oct 2017, In : British Journal of Cancer. 117, p. 1286-1294 9 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
8 Downloads (Pure)
2019

Can Haematology Blood Tests at Time of Diagnosis Predict Response to Neoadjuvant Treatment in Locally Advanced Rectal Cancer?

Ramsay, G., Ritchie, D. T., MacKay, C., Parnaby, C., Murray, G. & Samuel, L., Oct 2019, In : Digestive Surgery. 36, 6, p. 495–501 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2017

Randomized study of etirinotecan pegol versus irinotecan as second-line treatment for metastatic colorectal cancer

Lenz, H-J., Philip, P., Saunders, M., Kolevska, T., Mukherjee, K., Samuel, L., Bondarde, S., Dobbs, T., Tagliaferri, M., Hoch, U., Hannah, A. . & Berkowitz, M., Dec 2017, In : Cancer Chemotherapy and Pharmacology. 80, 6, p. 1161-1169 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2011

Toward shared care for people with cancer: developing the model with patients and GPs

Hall, S. J., Samuel, L. & Murchie, P., Oct 2011, In : Family Practice. 28, 5, p. 1-11 11 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)

Modifiable and fixed factors predicting quality of life in people with colorectal cancer

Gray, N. M., Hall, S. J., Browne, S., Macleod, U., Mitchell, E., Lee, A. J., Johnston, M., Wyke, S., Samuel, L., Weller, D. & Campbell, N. C., 24 May 2011, In : British Journal of Cancer. 104, p. 1697-1703 7 p.

Research output: Contribution to journalArticle

56 Citations (Scopus)
2016
Open Access
File
12 Citations (Scopus)
8 Downloads (Pure)
2020

The McCAVE Trial: Vanucizumab plus mFOLFOX-6 Versus Bevacizumab plus mFOLFOX-6 in Patients with Previously Untreated Metastatic Colorectal Carcinoma (mCRC)

Bendell, J. C., Sauri, T., Gracian, A. C., Alvarez, R., Lopez-Lopez, C., Garcia-Alfonso, P., Hussein, M., Limon Miron, M-L., Cervantes, A., Montagut, C., Santos Vivas, C., Bessudo, A., Plezia, P., Moons, V., Andel, J., Bennouna, J., van der Westhuizen, A., Samuel, L., Rossomanno, S., Boetsch, C. & 6 others, Lahr, A., Franjkovic, I., Heil, F., Lechner, K., Krieter, O. & Hurwitz, H., Mar 2020, In : Oncologist. 25, 3, p. e451-e459 9 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
3 Downloads (Pure)
2017

Natural killer-like signature observed post therapy in locally advanced rectal cancer is a determinant of pathological response and improved survival

Alderdice, M., Dunne, P. D., Cole, A. J., O'Reilly, P. G., McArt, D. G., Bingham, V., Fuchs, M-A., McQuaid, S., Loughrey, M. B., Murray, G. I., Samuel, L., Lawler, M., Wilson, R. H., Salto-Tellez, M. & Coyle, V. M., Sep 2017, In : Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 30, 9, p. 1287-1298 12 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
9 Downloads (Pure)
2018

Phase II study of the dual EGFR/HER3 inhibitor duligotuzumab (MEHD7945A) vs. cetuximab in combination with FOLFIRI in RAS wild-type metastatic colorectal cancer

Hill, A. G., Findlay, M., Burge, M., Jackson, C., Garcia Alfonso, P., Samuel, L., Ganju, V., Karthaus, M., Amatu, A., Jeffrey, M., Di Bartolomeo, M., Bridgewater, J., Coveler, A., Hidalgo, M., Kapp, A., Sufan, R., McCall, B., Hanley, W., Penuel, E., Pirzkall, A. & 1 others, Tabernero, J., May 2018, In : Clinical Cancer Research. 24, 10, p. 2276-2284 9 p.

Research output: Contribution to journalArticle

Open Access
File
11 Citations (Scopus)
6 Downloads (Pure)
2015
Open Access
File
33 Citations (Scopus)
6 Downloads (Pure)
2020

Hypoxia PET/CT and Colorectal Cancer: A Case Report

Laws, K., Murray, G. I., Kerr, K., McKiddie, F., Dall'angelo, S., Zanda, M., Fleming, I. & Samuel, L., 12 Aug 2020, In : Journal of Case Reports and Images in Oncology. 1(1), 2-5, 5 p.

Research output: Contribution to journalArticle

Open Access
File
2015

Effect of longer health service provider delays on stage at diagnosis and mortality in symptomatic breast cancer

Murchie, P., Raja, E. A., Lee, A. J., Brewster, D. H., Campbell, N. C., Gray, N. M., Ritchie, L. D., Robertson, R. & Samuel, L., Jun 2015, In : Breast. 24, 3, p. 248-255 8 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
12 Downloads (Pure)
2018

Transcriptional subtyping and CD8 immunohistochemistry identifies poor prognosis stage II/III colorectal cancer patients who benefit from adjuvant chemotherapy

Allen, W. L., Dunne, P. D., McDade, S., Scanlon, E., Loughrey, M., Coleman, H., McCann, C., McLaughlin, K., Nemeth, Z., Syed, N., Jithesh, P., Arthur, K., Wilson, R., Coyle, V., McArt, D., Murray, G., Samuel, L., Nuciforo, P., Jimenez, J., Argiles, G. & 12 others, Dienstmann, R., Tabernero, J., Picariello, L., Messerini, L., Nobili, S., Mini, E., Sheahan, K., Ryan, E., Johnston, P. G., Van Schaeybroeck, S., Lawler, M. & Longley, D. B., 2018, In : JCO Precision Oncology. 2018, 2, p. 1-15 15 p.

Research output: Contribution to journalArticle

Open Access
File
12 Citations (Scopus)
9 Downloads (Pure)
2020

Image-based consensus molecular subtype (imCMS) classification of colorectal cancer using deep learning

Sirinukunwattana, K., Domingo, E., Richman, S., Redmond, K. L., Blake, A., Verrill, C., Leedham, S. J., Chatzipli, A., Hardy, C., Whalley, C., Wu, C-H., Beggs, A. D., McDermott, U., Dunne, P. D., Meade, A. A., Walker, S. M., Murray, G., Samuel, L. M., Seymour, M., Tomlinson, I. & 4 others, Quirke, P., Maughan, T., Rittscher, J. & Koelzer, V. H., 20 Jul 2020, In : Gut.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
2018

Inhibition of EGFR, HER2, and HER3 signalling in patients with colorectal cancer wild-type for BRAF, PIK3CA, KRAS, and NRAS (FOCUS4-D): a phase 2–3 randomised trial

Adams, R., Brown, E., Brown, L., Butler, R., Falk, S., Fisher, D., Kaplan, R., Quirke, P., Richman, S., Samuel, L., Seligman, J., Seymour, M., Shui, K. K., Wasan, H., Wilson, R. & Maughan, T., Mar 2018, In : The Lancet Gastroenterology & Hepatology. 3, 3, p. 162–171 9 p.

Research output: Contribution to journalArticle

Open Access
File
19 Citations (Scopus)
7 Downloads (Pure)

Stochastic Pharmacokinetic/Pharmacodynamic Modeling for Assessing the Systemic Health Risk of Perfluorooctanoate (PFOA)

Convertino, C., Church, T., Olsen, G., Liu, Y., Doyle, E., Elcombe, C., Barnett, A., Samuel, L., MacPherson, I. & Evans, T., 1 May 2018, In : Toxicological Sciences. 163, 1, p. 293-306 14 p.

Research output: Contribution to journalArticle

Open Access
File
15 Citations (Scopus)
7 Downloads (Pure)
2013

Developing a community-based intervention to improve quality of life in people with colorectal cancer: A complex intervention development study

Gray, N. M., Allan, J. L., Murchie, P., Browne, S., Hall, S., Hubbard, G., Johnston, M., Lee, A. J., McKinley, A., Una, M., Presseau, J., Samuel, L., Wyke, S. & Campbell, N. C., 11 Apr 2013, In : BMJ Open. 3, 4, 8 p., e002596.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
6 Downloads (Pure)
2018

Neoadjuvant Anal Cancer VMAT: Lumbrosacral Plexus Dose Volume Histograms with Standard & Escalated Doses proposed in the ACT5 trial.

Findlay, E., Al-Hadjri, T., Wells, L. & Samuel, L., 20 Apr 2018.

Research output: Contribution to conferencePoster

Open Access
2020

Young-onset colorectal cancer in the North East of Scotland: survival, clinico- pathological features and genetics

Perrott, S., Laurie, K., Laws, K., Johnes, A., Miedzybrodzka, Z. & Samuel, L., 10 Feb 2020, In : BMC Cancer. 20, 108.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
4 Downloads (Pure)