Find Research Outputs — The University of Aberdeen

2017

Design, synthesis, in vitro characterization and preliminary imaging studies on fluorinated bile acid derivatives as PET tracers to study hepatic transporters

Testa, A., Dall'Angelo, S., Mingarelli, M., Augello, A., Schweiger, L., Welch, A. E., Elmore, C. S., Sharma, P. & Zanda, M., 1 Feb 2017, In: Bioorganic & Medicinal Chemistry. 25, 3, p. 963-976 14 p.

Research output: Contribution to journal › Article › peer-review

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11 Citations (Scopus)

9 Downloads (Pure)

Synthesis and Superpotent Anticancer Activity of Tubulysins Carrying Non-hydrolysable N-Substituents on Tubuvaline

Sani, M., Lazzari, P., Folini, M., Spiga, M., Zuco, V., De Cesare, M., Manca, I., Dall'Angelo, S., Frigerio, M., Usai, I., Testa, A., Zaffaroni, N. & Zanda, M., 27 Apr 2017, In: Chemistry : a European Journal. 23, 24, p. 5842-5850 9 p.

Research output: Contribution to journal › Article › peer-review

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5 Citations (Scopus)

9 Downloads (Pure)

2013

Tumour imaging by Positron Emission Tomography using fluorinase generated 5-[18F]fluoro-5-deoxyribose as a novel tracer

Dall'Angelo, S., Bandaranayaka, N., Windhorst, A. D., Vugts, D., van der Born, D., Onega, M., Schweiger, L. F., Zanda, M. & O'Hagan, D., May 2013, In: Nuclear Medicine and Biology. 40, 4, p. 464-470 7 p.

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

2017

A New Class of Fluorinated A_2A Adenosine Receptor Agonist with Application to Last-Step Enzymatic ¹⁸F Fluorination for PET Imaging

Lowe, P. T., Dall'Angello, S., Mulder-Krieger, T., Ijzerman, A. P., Zanda, M. & O'Hagan, D., 2 Nov 2017, In: ChemBioChem. 18, 21, p. 2156-2164 9 p.

Research output: Contribution to journal › Article › peer-review

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8 Citations (Scopus)

10 Downloads (Pure)

Synthesis, radio-synthesis and in vitro evaluation of terminally fluorinated derivatives of HU-210 and HU-211 as novel candidate PET tracers

Zanato, C., Pelagalli, A., Marwick, K. F. M., Piras, M., Dall'Angelo, S., Spinaci, A., Pertwee, R. G., Wyllie, D. J. A., Hardingham, G. E. & Zanda, M., 2017, In: Organic & Biomolecular Chemistry. 15, 9, p. 2086-2096 11 p.

Research output: Contribution to journal › Article › peer-review

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3 Citations (Scopus)

9 Downloads (Pure)

2013

Molecular insights into bacteroid development during Rhizobium-legume symbiosis

Haag, A. F., Arnold, M. F. F., Myka, K. K., Kerscher, B., Dall'angelo, S., Zanda, M., Mergaert, P. & Ferguson, G. P., May 2013, In: FEMS Microbiology Reviews. 37, 3, p. 364-383 20 p.

Research output: Contribution to journal › Article › peer-review

66 Citations (Scopus)

2020

Design, synthesis, radiosynthesis and biological evaluation of Fenretinide analogues as anticancer and metabolic syndromepreventive agents

Zanda, M., Patruno, I., Thompson, D., Dall'angelo, S., Windhorst, A. D., Vugts, D. J., Poot, A. J. & Mody, N., 19 Aug 2020, In: ChemMedChem. 15, 16, p. 1579-1590 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

A Weakened Immune Response to Synthetic Exo-Peptides Predicts a Potential Biosecurity Risk in the Retrieval of Exo-Microorganisms

Schaefer, K., Dambuza, I. M., Dall'angelo, S., Trembleau, L., Zanda, M., Brown, G. D., Netea, M. G. & Gow, N. A. R., 17 Jul 2020, In: Microorganisms. 8, 7, 14 p., 1066.

Research output: Contribution to journal › Article › peer-review

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2 Downloads (Pure)

2019

Enzymatic radiosynthesis of a ¹⁸F-Glu-Ureido-Lys ligand for the prostate-specific membrane antigen (PSMA)

Lowe, P. T., Dall'Angelo, S., Fleming, I. N., Piras, M., Zanda, M. & O'Hagan, D., 2019, In: Organic & Biomolecular Chemistry. 17, 6, p. 1480-1486 7 p.

Research output: Contribution to journal › Article › peer-review

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4 Citations (Scopus)

3 Downloads (Pure)

2016

Last-step enzymatic [18F]-fluorination of cysteine-tethered RGD peptides using modified Barbas linkers

Zhang, Q., Dall'Angelo, S., Fleming, I. N., Schweiger, L. F., Zanda, M. & O'Hagan, D., 25 Jul 2016, In: Chemistry : a European Journal. 22, 31, p. 10998-11004 7 p.

Research output: Contribution to journal › Article › peer-review

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18 Citations (Scopus)

7 Downloads (Pure)

2017

High Affinity “Click” RGD Peptidomimetics as Radiolabeled Probes for Imaging αvβ3 Integrin

Piras, M., Testa, A., Fleming, I. N., Dall'Angelo, S., Andriu, A., Menta, S., Mori, M., Brown, G. D., Forster, D., Williams, K. J. & Zanda, M., 20 Jul 2017, In: ChemMedChem. 12, 14, p. 1142-1151 10 p.

Research output: Contribution to journal › Article › peer-review

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6 Citations (Scopus)

11 Downloads (Pure)

2020

Hypoxia PET/CT and Colorectal Cancer: A Case Report

Laws, K., Murray, G. I., Kerr, K., McKiddie, F., Dall'angelo, S., Zanda, M., Fleming, I. & Samuel, L., 12 Aug 2020, In: Journal of Case Reports and Images in Oncology. 1(1), 2-5, 5 p.

Research output: Contribution to journal › Article › peer-review

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1 Downloads (Pure)

2017

Synthesis and radio-synthesis of prospective 2-nitroimidazole hypoxia PET tracers via thiazolidine ligation with 5-fluorodeoxyribose (FDR)

Musolino, M., Dall'angelo, S. & Zanda, M., 2017, In: SynOpen. 1, 1, p. 173-179 7 p.

Research output: Contribution to journal › Article › peer-review

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7 Downloads (Pure)

2011

Protection of Sinorhizobium against host cysteine-rich antimicrobial peptides is critical for symbiosis

Haag, A. F., Baloban, M., Sani, M., Kerscher, B., Pierre, O., Farkas, A., Longhi, R., Boncompagni, E., Hérouart, D., Dall'angelo, S., Kondorosi, E., Zanda, M., Mergaert, P. & Ferguson, G. P., 4 Oct 2011, In: PLoS Biology. 9, 10, 10 p., e1001169.

Research output: Contribution to journal › Article › peer-review

102 Citations (Scopus)

2020

Design, synthesis, conjugation and reactivity of novel trans,trans-1,5-cyclooctadiene-derived bioorthogonal linkers

Longo, B., Zanato, C., Piras, M., Dall'angelo, S., Windhorst, A. D., Vugts, D., Baldassarre, M. & Zanda, M., 16 Sep 2020, In: Bioconjugate Chemistry. 31, 9, p. 2201-2210 10 p.

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

2019

The Trifluoromethyl Group as a Bioisosteric Replacement of the Aliphatic Nitro Group in CB1 Receptor Positive Allosteric Modulators (PAMs)

Tseng, C-C., Baillie, G., Donvito, G., Mustafa, M. A., Juola, S. E., Zanato, C., Massarenti, C., Dall'angelo, S., Harrison, W. T. A., Lichtman, A. H., Ross, R. A., Zanda, M. & Greig, I. R., 2019, In: Journal of Medicinal Chemistry. 62, 10, p. 5049-5062 14 p.

Research output: Contribution to journal › Article › peer-review

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11 Citations (Scopus)

4 Downloads (Pure)

2020

Widespread tissue hypoxia dysregulates cell and metabolic pathways in SMA

Hernandez Gerez, E., Dall'angelo, S., Collinson, J. M., Fleming, I. N. & Parson, S. H., Sep 2020, In: Annals of Clinical and Translational Neurology. 7, 9, p. 1580-1593 14 p.

Research output: Contribution to journal › Article › peer-review

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2013

¹⁸F-barbiturates are PET tracers with diagnostic potential in Alzheimer's disease

Calamai, E., Dall'Angelo, S., Koss, D., Domarkas, J., McCarthy, T. J., Mingarelli, M., Riedel, G., Schweiger, L. F., Welch, A. E., Platt, B. & Zanda, M., 2013, In: Chemical Communications. 49, 8, p. 792-794 3 p.

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

2020

[18F]ZCDD083: a PFKFB3-targeted PET tracer for atherosclerotic plaque imaging

De Dominicis, C., Perrotta, P., Dall'angelo, S., Wyffels, L., Staelens, S., de Meyer, G. R. Y. & Zanda, M., 14 May 2020, In: ACS Medicinal Chemistry Letters. 11, 5, p. 933-939 7 p.

Research output: Contribution to journal › Article › peer-review

2012

[18F]-5-Fluoro-5-deoxyribose, an efficient peptide bioconjugation ligand for positron emission tomography (PET) imaging

Li, X. G., Dall'Angelo, S., Schweiger, L. F., Zanda, M. & O'Hagan, D., 28 May 2012, In: Chemical Communications. 48, 43, p. 5247-5249 3 p.

Research output: Contribution to journal › Article › peer-review

28 Citations (Scopus)

Role of cysteine residues and disulfide bonds in the activity of a legume root nodule-specific, cysteine-rich peptide

Haag, A. F., Kerscher, B., Dall'Angelo, S., Sani, M., Longhi, R., Baloban, M., Wilson, H. M., Mergaert, P., Zanda, M. & Ferguson, G. P., 30 Mar 2012, In: The Journal of Biological Chemistry. 287, 14, p. 10791-10798 8 p.

Research output: Contribution to journal › Article › peer-review

49 Citations (Scopus)

2013

Pyrazole-type Cannabinoid Ligands conjugated with Fluoro-deoxy-carbohydrates as Potential PET-Imaging Agents: Synthesis and CB1/CB2 receptor affinity evaluation

Frau, S., Dall'Angelo, S., Baillie, G. L., Ross, R. A., Pira, M., Tseng, C-C., Lazzari, P. & Zanda, M., Aug 2013, In: Journal of Fluorine Chemistry. 152, p. 166-172 7 p.

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

2020

4,4,16-Trifluoropalmitate: design, synthesis, tritiation, radiofluorination and pre-clinical PET imaging studies on myocardial fatty acid oxidation

Colombano, A., Dall'angelo, S., Kingston, L., Grönberg, G., Correia, C., Passannante, R., Baz, Z., Morcillo, M. A., Elmore, C., Llop, J. & Zanda, M., 3 Dec 2020, In: ChemMedChem. 15, 23, p. 2317-2331 15 p.

Research output: Contribution to journal › Article › peer-review

2013

Efficient bioconjugation of 5-fluoro-5-deoxy-ribose (FDR) to RGD peptides for positron emission tomography (PET) imaging of αvβ3 integrin receptor

Dall'angelo, S., Zhang, Q., Fleming, I. N., Piras, M., Schweiger, L. F., O'Hagan, D. & Zanda, M., 3 Jun 2013, In: Organic & Biomolecular Chemistry. 27, 11, p. 4551-4558 8 p.

Research output: Contribution to journal › Article › peer-review

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22 Citations (Scopus)

42 Downloads (Pure)

2016

NGR Tumor-Homing Peptides: Structural Requirements for Effective APN (CD13) Targeting

Graziadio, A., Zanda, M., Frau, S., Fleming, I. N., Musolino, M., Dall'Angelo, S., Baldassarre, M. & Piras, M., 18 May 2016, In: Bioconjugate Chemistry. 27, 5, p. 1332-1340 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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18 Citations (Scopus)

7 Downloads (Pure)

2017

Synthesis and hyperpolarisation of eNOS substrates for quantification of NO production by (1)H NMR spectroscopy

Fernandez Diaz-Rullo, F., Zamberlan, F., Mewis, R. E., Fekete, M., Broche, L., Cheyne, L. A., Dall'Angelo, S., Duckett, S. B., Dawson, D. & Zanda, M., 15 May 2017, In: Bioorganic & Medicinal Chemistry. 25, 10, p. 2730-2742 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

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5 Citations (Scopus)

7 Downloads (Pure)

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