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  • Graeme Murray

Recent advances in understanding the roles of matrix metalloproteinases in tumour invasion and metastasis

Conlon, G. A. & Murray, G. I., Apr 2019, In : The Journal of pathology. 247, 5, p. 629-640 12 p.

Research output: Contribution to journalArticle

Open Access
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33 Citations (Scopus)
2 Downloads (Pure)

Reduced LIMK2 expression in colorectal cancer reflects its role in limiting stem cell proliferation

Lourenco, F. C., Munro, J., Brown, J., Cordero, J., Stefanatos, R., Strathdee, K., Orange, C., Feller, S. M., Sansom, O. J., Vidal, M., Murray, G. I. & Olson, M. F., Mar 2014, In : Gut. 63, 3, p. 480-493 14 p.

Research output: Contribution to journalArticle

Open Access
File
16 Citations (Scopus)
7 Downloads (Pure)

Regulation of cellular sphingosine-1-phosphate by sphingosine kinase 1 and sphingosine-1-phopshate lyase determines chemotherapy resistance in gastroesophageal cancer

Matula, K., Collie-Duguid, E., Murray, G., Parikh, K., Grabsch, H. I., Tan, P., Lalwani, S., Garau, R., Ong, Y., Bain, G., Dahle-Smith, A., Urquhart, G., Bielawski, J., Finnegan, M. & Petty, R., 2015, In : BMC Cancer. 15, 762, 14 p., 762.

Research output: Contribution to journalArticle

Open Access
File
30 Citations (Scopus)
7 Downloads (Pure)

ROS production and NF-κB activation triggered by RAC1 facilitate WNT-driven intestinal stem cell proliferation and colorectal cancer initiation

Myant, K. B., Cammereri, P., McGhee, E. J., Ridgway, R. A., Huels, D. J., Cordero, J. B., Schwitalla, S., Kalna, G., Ogg, E-L., Athineos, D., Timpson, P., Vidal, M., Murray, G. I., Greten, F. R., Anderson, K. I. & Sansom, O. J., 6 Jun 2013, In : Cell Stem Cell. 12, 6, p. 761-773 13 p.

Research output: Contribution to journalArticle

216 Citations (Scopus)

Sensitivity of Colorectal Cancer to Arginine Deprivation Therapy is Shaped by Differential Expression of Urea Cycle Enzymes

Alexandrou, C., Al-Aqbi, S. S., Higgins, J. A., Boyle, W., Karmokar, A., Andreadi, C., Luo, J-L., Moore, D. A., Viskaduraki, M., Blades, M., Murray, G. I., Howells, L. M., Thomas, A., Brown, K., Cheng, P. N. & Rufini, A., 14 Aug 2018, In : Scientific Reports. 8, p. 1-14 14 p., 12096.

Research output: Contribution to journalArticle

Open Access
File
11 Citations (Scopus)
6 Downloads (Pure)

The adaptive immune and immune checkpoint landscape of neoadjuvant treated esophageal adenocarcinoma using digital pathology quantitation

Humphries, M. P., Craig, S. G., Kacprzyk, R., Fisher, N. C., Bingham, V., McQuaid, S., Murray, G. I., McManus, D., Turkington, R. C., James, J. & Salto-Tellez, M., 1 Jun 2020, In : BMC Cancer. 20, 11 p., 500.

Research output: Contribution to journalArticle

Open Access
File
2 Downloads (Pure)
Open Access
File
10 Citations (Scopus)
9 Downloads (Pure)
Open Access
File
12 Citations (Scopus)
8 Downloads (Pure)

The expression and prognostic significance of retinoic acid metabolising enzymes in colorectal cancer

Brown, G. T., Cash, B. G., Blihoghe, D., Johansson, P., Alnabulsi, A. & Murray, G. I., 7 Mar 2014, In : PloS ONE. 9, 3, 12 p., e90776.

Research output: Contribution to journalArticle

Open Access
File
28 Citations (Scopus)
5 Downloads (Pure)

The expression of brown fat associated proteins in colorectal cancer and the relationship of uncoupling protein 1 with prognosis

Alnabulsi, A., Cash, B., Hu, Y., Silina, L., Alnabulsi, A. & Murray, G. I., 15 Aug 2019, In : International Journal of Cancer. 145, 4, p. 1138-1147 10 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
3 Downloads (Pure)
44 Citations (Scopus)

The Hippo effector TAZ (WWTR1) transforms myoblasts and TAZ abundance is associated with reduced survival in embryonal rhabdomyosarcoma

Mohamed, A., Sun, C., De Mello, V., Selfe, J., Missiaglia, E., Shipley, J., Murray, G. I., Zammit, P. S. & Wackerhage, H., Sep 2016, In : The Journal of pathology. 240, 1, p. 3-14 12 p.

Research output: Contribution to journalArticle

Open Access
File
19 Citations (Scopus)
7 Downloads (Pure)

The Hippo Transducer YAP1 Transforms Activated Satellite Cells and Is a Potent Effector of Embryonal Rhabdomyosarcoma Formation

Tremblay, A. M., Missiaglia, E., Galli, G. G., Hettmer, S., Urcia, R., Carrara, M., Judson, R. N., Thway, K., Nadal, G., Selfe, J. L., Murray, G. I., Calogero, R. A., De Bari, C., Zammit, P. S., Delorenzi, M., Wagers, A. J., Shipley, J., Wackerhage, H. & Camargo, F. D., 11 Aug 2014, In : Cancer Cell. 26, 2, p. 273-287 15 p.

Research output: Contribution to journalArticle

96 Citations (Scopus)

The inflammatory microenvironment in colorectal neoplasia

McLean, M. H., Murray, G. I., Stewart, K. N., Norrie, G., Mayer, C., Hold, G. L., Thomson, J., Fyfe, N., Hope, M., Mowat, N. A. G., Drew, J. E. & El-Omar, E. M., 7 Jan 2011, In : PloS ONE. 6, 1, 8 p., e15366.

Research output: Contribution to journalArticle

Open Access
File
110 Citations (Scopus)
7 Downloads (Pure)

The prognostic role of Lymph Node Ratio (LNR) and other indicators in patients undergoing potentially curative rectal cancer resection

MacLeod, C., Mackay, C., Ramsay, G., Murray, G. I. & Parnaby, C., Jun 2017.

Research output: Contribution to conferencePoster

The proteomics of colorectal cancer: identification of a protein signature associated with prognosis

O'Dwyer, D., Ralton, L. D., O'Shea, A. & Murray, G. I., 18 Nov 2011, In : PloS ONE. 6, 11, 15 p., e27718.

Research output: Contribution to journalArticle

Open Access
File
71 Citations (Scopus)
5 Downloads (Pure)

The proteomics of formalin-fixed wax-embedded tissue

Cilia Vincenti, D. & Murray, G. I., Apr 2013, In : Clinical Biochemistry. 46, 6, p. 546-551 6 p.

Research output: Contribution to journalLiterature review

14 Citations (Scopus)

The role of gene regulatory networks in promoting cancer progression and metastasis

Caroline, C. & Murray, G. I., Apr 2014, In : Future Oncology. 10, 5, p. 735-748 14 p.

Research output: Contribution to journalLiterature review

9 Citations (Scopus)

The role of lysyl oxidase in SRC-dependent proliferation and metastasis of colorectal cancer

Baker, A-M., Cox, T. R., Bird, D., Lang, G., Murray, G. I., Sun, X-F., Southall, S. M., Wilson, J. R. & Erler, J. T., 2 Mar 2011, In : Journal of the National Cancer Institute. 103, 5, p. 407-424 18 p.

Research output: Contribution to journalArticle

122 Citations (Scopus)

The use of formalin fixed wax embedded tissue for proteomic analysis

Ralton, L. D. & Murray, G. I., Apr 2011, In : Journal of Clinical Pathology. 64, 4, p. 297-302 6 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

TIAM1 Antagonizes TAZ/YAP Both in the Destruction Complex in the Cytoplasm and in the Nucleus to Inhibit Invasion of Intestinal Epithelial Cells

Diamantopoulou, Z., White, G., Fadlullah, M. Z. H., Dreger, M., Pickering, K., Maltas, J., Ashton, G., MacLeod, R., Baillie, G. S., Kouskoff, V., Lacaud, G., Murray, G. I., Sansom, O. J., Hurlstone, A. F. L. & Malliri, A., 8 May 2017, In : Cancer Cell. 31, 5, p. 621-634 14 p.

Research output: Contribution to journalArticle

Open Access
File
31 Citations (Scopus)
6 Downloads (Pure)

Transcriptional subtyping and CD8 immunohistochemistry identifies poor prognosis stage II/III colorectal cancer patients who benefit from adjuvant chemotherapy

Allen, W. L., Dunne, P. D., McDade, S., Scanlon, E., Loughrey, M., Coleman, H., McCann, C., McLaughlin, K., Nemeth, Z., Syed, N., Jithesh, P., Arthur, K., Wilson, R., Coyle, V., McArt, D., Murray, G., Samuel, L., Nuciforo, P., Jimenez, J., Argiles, G. & 12 others, Dienstmann, R., Tabernero, J., Picariello, L., Messerini, L., Nobili, S., Mini, E., Sheahan, K., Ryan, E., Johnston, P. G., Van Schaeybroeck, S., Lawler, M. & Longley, D. B., 2018, In : JCO Precision Oncology. 2018, 2, p. 1-15 15 p.

Research output: Contribution to journalArticle

Open Access
File
12 Citations (Scopus)
9 Downloads (Pure)

Transporters for Antiretroviral Drugs in Colorectal CD4+ T Cells and Circulating α4β7 Integrin CD4+ T cells: Implications for HIV Microbicides

Mukhopadhya, I., Murray, G. I., Duncan, L., Yuecel, R., Shattock, R., Kelly, C., Iannelli, F., Pozzi, G., El-Omar, E., Hold, G. & Hijazi, K., 6 Sep 2016, In : Molecular Pharmaceutics. 13, 9, p. 3334-3340 7 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
7 Downloads (Pure)

Tumour expression of leptin is associated with chemotherapy resistance and therapy-independent prognosis in gastro-oesophageal adenocarcinomas

Bain, G. H., Collie-Duguid, E., Murray, G. I., Gilbert, F. J., Denison, A., McKiddie, F., Ahearn, T., Fleming, I., Leeds, J., Phull, P., Park, K., Nanthakumaran, S., Grabsch, H. I., Tan, P., Welch, A., Schweiger, L., Dahle-Smith, A., Urquhart, G., Finegan, M., Matula, K. M. & 1 others, Petty, R. D., 18 Mar 2014, In : British Journal of Cancer. 110, 6, p. 1525-1534 10 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

β-Glucan exacerbates allergic airway responses to house dust mite allergen

Hadebe, S., Kirstein, F., Fierens, K., Redelinghuys, P., Murray, G. I., Williams, D. L., Lambrecht, B. N., Brombacher, F. & Brown, G. D., 2 Apr 2016, In : Respiratory Research. 17, p. 1-3 3 p., 35.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
6 Downloads (Pure)