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  • John Speakman

Limits to sustained energy intake XXIX: the case of the golden hamster (Mesocricetus auratus)

Ohrnberger, S. A., Hambly, C., Speakman, J. R. & Valencak, T. G., 31 Oct 2018, In : Journal of Experimental Biology. 221, 21, 9 p., jeb183749.

Research output: Contribution to journalArticle

Open Access
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2 Citations (Scopus)
2 Downloads (Pure)

Limits to sustained energy intake XXV: milk energy output and thermogenesis in Swiss mice lactating at thermoneutrality

Zhao, Z-J., Li, L., Yang, D-B., Chi, Q-S., Hambly, C. & Speakman, J. R., 2016, In : Scientific Reports. 6, p. 1-18 18 p., 31626.

Research output: Contribution to journalArticle

Open Access
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7 Citations (Scopus)
7 Downloads (Pure)
Open Access
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4 Citations (Scopus)
8 Downloads (Pure)
Open Access
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2 Citations (Scopus)
3 Downloads (Pure)

Limits to Sustained Energy Intake XXXI: Effect of Graded Levels of Dietary Fat on Lactation Performance in Swiss Mice

Huang, Y., Mendoza, J. O., Hambly, C., Li, B., Jin, Z., Li, L., Madizi, M., Hu, S. & Speakman, J. R., 22 May 2020, In : Journal of Experimental Biology. 223, 10, 13 p., 221911.

Research output: Contribution to journalArticle

Low Citrate Synthase Activity Is Associated with Glucose Intolerance and Lipotoxicity

Alhindi, Y., Vaanholt, L. M., Al-Tarrah, M., Gray, S. R., Speakman, J. R., Hambly, C., Alanazi, B. S., Gabriel, B. M., Lionikas, A. & Ratkevicius, A., 3 Mar 2019, In : Journal of Nutrition and Metabolism. 2019, 14 p., 8594825.

Research output: Contribution to journalArticle

Open Access
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3 Citations (Scopus)
8 Downloads (Pure)

Maximizing precision and accuracy of the doubly labeled water method via optimal sampling protocol, calculation choices, and incorporation of 17O measurements

Berman, E. S. F., Swibas, T., Kohrt, W. M., Catenacci, V. A., Creasy, S. A., Melanson, E. L. & Speakman, J. R., 2020, In : European Journal of Clinical Nutrition. 74, 3, p. 454-464 11 p.

Research output: Contribution to journalArticle

Measured energy content of frequently purchased restaurant meals: multi-country cross sectional study

Roberts, S. B., Das, S. K., Suen, V. M. M., Pihlajamäki, J., Kuriyan, R., Steiner-Asiedu, M., Taetzsch, A., Anderson, A. K., Silver, R. E., Barger, K., Krauss, A., Karhunen, L., Zhang, X., Hambly, C., Schwab, U., Triffoni-Melo, A. D. T., Taylor, S. F., Economos, C., Kurpad, A. V. & Speakman, J. R., 12 Dec 2018, In : BMJ (Clinical research ed.). 363, k4864.

Research output: Contribution to journalArticle

Open Access
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12 Citations (Scopus)
5 Downloads (Pure)

Measures of Healthspan as Indices of Aging in Mice-A Recommendation

Richardson, A., Fischer, K. E., Speakman, J. R., de Cabo, R., Mitchell, S. J., Peterson, C. A., Rabinovitch, P., Chiao, Y. A., Taffet, G., Miller, R. A., Renteria, R. C., Bower, J., Ingram, D. K., Ladiges, W. C., Ikeno, Y., Sierra, F. & Austad, S. N., Apr 2016, In : The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. 71, 4, p. 427-430 4 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Metabolic changes over the course of aging in a mouse model of tau deposition

Joly-Amado, A., Serraneau, K. S., Brownlow, M., Marín de Evsikova, C., Speakman, J. R., Gordon, M. N. & Morgan, D., Aug 2016, In : Neurobiology of Aging. 44, p. 62-73 12 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Metabolic Syndrome Patients Have Lower Levels of Adropin When Compared With Healthy Overweight/Obese and Lean Subjects

Yosaee, S., Khodadost, M., Esteghamati, A., Speakman, J. R., Shidfar, F., Nazari, M. N., Bitarafan, V. & Djafarian, K., 1 Mar 2017, In : American Journal of Men's Health. 11, 2, p. 426-434 9 p.

Research output: Contribution to journalArticle

Open Access
13 Citations (Scopus)

Microbiota Depletion Impairs Thermogenesis of Brown Adipose Tissue and Browning of White Adipose Tissue

Li, B., Li, L., Li, M., Lam, S. M., Wang, G., Wu, Y., Zhang, H., Niu, C., Zhang, X., Liu, X., Hambly, C., Jin, W., Shui, G. & Speakman, J. R., 5 Mar 2019, In : Cell Reports. 26, 10, p. 2720-2737 18 p.

Research output: Contribution to journalArticle

Open Access
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32 Citations (Scopus)
6 Downloads (Pure)

No energetic cost of tuberculosis infection in European badgers (Meles meles)

Barbour, K., McClune, D. W., Delahay, R. J., Speakman, J. R., McGowan, N. E., Kostka, B., Montgomery, I. W., Marks, N. J. & Scantlebury, D. M., Dec 2019, In : Journal of Animal Ecology. 88, 12, p. 1973-1985 12 p.

Research output: Contribution to journalArticle

No impact of hunger on male perception of female physical attractiveness in relation to adiposity: a randomized controlled trial

Jin, Z., Wang, G., Hu, S. & Speakman, J. R., Feb 2020, In : International Journal of Obesity. 44, p. 418-427 10 p.

Research output: Contribution to journalArticle

No seasonal variation in physical activity of Han Chinese living in Beijing

Wang, G., Li, B., Zhang, X., Niu, C., Li, J., Li, L. & Speakman, J. R., 17 Apr 2017, In : The International Journal of Behavioral Nutrition and Physical Activity. 14, 48.

Research output: Contribution to journalArticle

Open Access
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10 Citations (Scopus)
9 Downloads (Pure)

Nutrition and its role in human evolution

James, W. P. T., Johnson, R. J., Speakman, J. R., Wallace, D. C., Frühbeck, G., Iverson, P. O. & Stover, P. J., May 2019, In : Journal of Internal Medicine. 285, 5, p. 533-549 17 p.

Research output: Contribution to journalReview article

Open Access
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8 Citations (Scopus)
2 Downloads (Pure)

Obesity and thermoregulation

Speakman, J. R., 2018, In : Handbook of clinical neurology. 156, p. 431-443 13 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

On the origin of obesity: identifying the biological, environmental and cultural drivers of genetic risk among human populations

Qasim, A., Turcotte, M., de Souza, R. J., Samaan, M. C., Champredon, D., Dushoff, J., Speakman, J. R. & Meyre, D., 28 Feb 2018, In : Obesity Reviews. 19, 2, p. 121-149 29 p.

Research output: Contribution to journalReview article

45 Citations (Scopus)

Oxidative costs of reproduction: Oxidative stress in mice fed standard and low antioxidant diets

Vaanholt, L. M., Milne, A., Zheng, Y., Hambly, C., Mitchell, S. E., Valencak, T. G., Allison, D. B. & Speakman, J. R., 1 Feb 2016, In : Physiology and Behavior. 154, p. 1-7 7 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Oxidative costs of reproduction in mouse strains selected for different levels of food intake and which differ in reproductive performance

Jothery, A. H. A., Vaanholt, L. M., Mody, N., Arnous, A., Lykkesfeldt, J., Bünger, L., Hill, W. G., Mitchell, S. E., Allison, D. B. & Speakman, J. R., 14 Nov 2016, In : Scientific Reports. 6, 36353.

Research output: Contribution to journalArticle

Open Access
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6 Citations (Scopus)
6 Downloads (Pure)

Partitioning the variance in calorie restriction-induced weight and fat loss in outbred mice

Vaanholt, L. M., Lane, J. E., Garner, B. & Speakman, J. R., Oct 2016, In : Obesity. 24, 10, p. 2111-2117 7 p.

Research output: Contribution to journalArticle

Open Access
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5 Downloads (Pure)

Photoperiod induced obesity in the Brandt's vole (Lasiopodomys brandtii): a model of 'healthy obesity'?

Liu, X-Y., Yang, D-B., Xu, Y-C., Gronning, M. O. L., Zhang, F., Wang, D-H. & Speakman, J. R., 2 Nov 2016, In : Disease Models & Mechanisms. 9, 11, p. 1357-1366 10 p.

Research output: Contribution to journalArticle

Open Access
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4 Citations (Scopus)
5 Downloads (Pure)

Pre- and post-diagnosis body mass index and heart failure mortality: a dose-response meta-analysis of observational studies reveals greater risk of being underweight than being overweight

Milajerdi, A., Djafarian, K., Shab-Bidar, S. & Speakman, J. R., 28 Feb 2019, In : Obesity Reviews. 20, 2, p. 252-261 11 p.

Research output: Contribution to journalReview article

4 Citations (Scopus)

Probiotics Reduce the Risk of Antibiotic-Associated Diarrhea in Adults (18–64 Years) but Not the Elderly (>65 Years): A Meta-Analysis

Jafarnejad, S., Shab-Bidar, S., Speakman, J. R., Parastui, K., Daneshi-Maskooni, M. & Djafarian, K., Aug 2016, In : Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition. 31, 4, p. 502-513 12 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Progress and challenges in analyzing rodent energy expenditure

Fernández-Verdejo, R., Ravussin, E., Speakman, J. R. & Galgani, J. E., Sep 2019, In : Nature methods. 16, p. 797-799 3 p.

Research output: Contribution to journalComment/debate

6 Citations (Scopus)

Reconstitution of UCP1 using CRISPR/Cas9 in the white adipose tissue of pigs decreases fat deposition and improves thermogenic capacity

Zheng, Q., Lin, J., Huang, J., Zhang, H., Zhang, R., Zhang, X., Cao, C., Hambly, C., Qin, G., Yao, J., Song, R., Jia, Q., Wang, X., Li, Y., Zhang, N., Piao, Z., Ye, R., Speakman, J. R., Wang, H., Zhou, Q. & 3 others, Wang, Y., Jin, W. & Zhao, J., 2017, In : PNAS. 114, 45, p. 9474-9482 9 p.

Research output: Contribution to journalArticle

Open Access
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57 Citations (Scopus)
5 Downloads (Pure)

Regulation of intestinal growth in response to variations in energy supply and demand

Nilaweera, K. N. & Speakman, J. R., Dec 2018, In : Obesity Reviews. 19, Suppl 1, p. 61-72 12 p.

Research output: Contribution to journalReview article

Open Access
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4 Citations (Scopus)
6 Downloads (Pure)

Renal cell carcinoma survival and body mass index: a dose-response meta-analysis reveals another potential paradox within a paradox

Bagheri, M., Speakman, J. R., Shemirani, F. & Djafarian, K., Dec 2016, In : International Journal of Obesity. 40, 12, p. 1817-1822 6 p.

Research output: Contribution to journalReview article

17 Citations (Scopus)

Reply to VI Kraak

Speakman, J. R. & Mazidi, M., 1 Feb 2018, In : The American Journal of Clinical Nutrition. 107, 2, p. 290-291 2 p.

Research output: Contribution to journalComment/debate

Response to 'Fat is not just an energy store'

Speakman, J. R., 22 Jun 2018, In : Journal of Experimental Biology. 221, 12, jeb184499.

Research output: Contribution to journalArticle

Seasonal changes in energy expenditure, body temperature and activity patterns in llamas (Lama glama)

Riek, A., Brinkmann, L., Gauly, M., Perica, J., Ruf, T., Arnold, W., Hambly, C., Speakman, J. R. & Gerken, M., 2018, In : Scientific Reports. 7, p. 1-12 12 p., 7600.

Research output: Contribution to journalArticle

Open Access
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11 Citations (Scopus)
7 Downloads (Pure)

Sex difference in physical activity, energy expenditure and obesity driven by a subpopulation of hypothalamic POMC neurons

Burke, L. K., Doslikova, B., D'Agostino, G., Greenwald-Yarnell, M., Georgescu, T., Chianese, R., Martinez de Morentin, P. B., Ogunnowo-Bada, E., Cansell, C., Valencia-Torres, L., Garfield, A. S., Apergis-Schoute, J., Lam, D. D., Speakman, J. R., Rubinstein, M., Low, M. J., Rochford, J. J., Myers, M. G., Evans, M. L. & Heisler, L. K., Mar 2016, In : Molecular Metabolism. 5, 3, p. 245-252 8 p.

Research output: Contribution to journalArticle

Open Access
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39 Citations (Scopus)
8 Downloads (Pure)

Sex differences in the effect of fish-oil supplementation on the adaptive response to resistance exercise training in older people: a randomized controlled trial

Da Boit, M., Sibson, R., Sivasubramaniam, S., Meakin, J. R., Greig, C. A., Aspden, R., Thies, F., Jeromson, S., Hamilton, D. L., Speakman, J. R., Hambly, C., Mangoni, A. A., Preston, T. & Gray, S. R., Jan 2017, In : The American Journal of Clinical Nutrition. 105, 1, p. 151-158 8 p.

Research output: Contribution to journalArticle

Open Access
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60 Citations (Scopus)
5 Downloads (Pure)

Switching off the furnace: brown adipose tissue and lactation

Król, E. & Speakman, J. R., Aug 2019, In : Molecular Aspects of Medicine. 68, p. 18-41 24 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Switching on the furnace: Regulation of heat production in brown adipose tissue

Li, L., Li, B., Li, M. & Speakman, J. R., Aug 2019, In : Molecular Aspects of Medicine. 68, p. 60-73 14 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Sympatric Atlantic puffins and razorbills show contrasting responses to adverse marine conditions during winter foraging within the North Sea

St John Glew, K., Wanless, S., Harris, M. P., Daunt, F., Erikstad, K. E., Strøm, H., Speakman, J. R., Kürten, B. & Trueman, C. N., 1 Nov 2019, In : Movement Ecology. 7, 14 p., 33.

Research output: Contribution to journalArticle

Open Access
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1 Citation (Scopus)
2 Downloads (Pure)

Testing the carbohydrate insulin model in mice: Erroneous critique does not alter previous conclusion

Speakman, J. R., Hu, S. & Togo, J., May 2020, In : Molecular Metabolism. 35, 2 p., 100961.

Research output: Contribution to journalComment/debate

Open Access
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The Assessment of Total Energy Expenditure During a 14-Day In-Season Period of Professional Rugby League Players Using the Doubly Labelled Water Method

Morehen, J. C., Bradley, W. J., Clarke, J., Twist, C., Hambly, C., Speakman, J. R., Morton, J. P. & Close, G. L., Oct 2016, In : International Journal of Sport Nutrition & Exercise Metabolism. 26, 5, p. 464-472 9 p.

Research output: Contribution to journalArticle

Open Access
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21 Citations (Scopus)
8 Downloads (Pure)

The carbohydrate-insulin model does not explain the impact of varying dietary macronutrients on the body weight and adiposity of mice

Hu, S., Wang, L., Togo, J., Yang, D., Xu, Y., Wu, Y., Douglas, A. & Speakman, J. R., Feb 2020, In : Molecular Metabolism. 32, p. 27-43 17 p.

Research output: Contribution to journalArticle

Open Access
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2 Citations (Scopus)
4 Downloads (Pure)

The effects of graded caloric restriction: XII. Comparison of mouse to human impact on cellular senescence in the colon

Fontana, L., Mitchell, S. E., Wang, B., Tosti, V., van Vliet, T., Veronese, N., Bertozzi, B., Early, D. S., Maissan, P., Speakman, J. R. & Demaria, M., Jun 2018, In : Aging Cell. 17, 3, e12746.

Research output: Contribution to journalArticle

Open Access
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14 Citations (Scopus)
9 Downloads (Pure)

The effects of graded levels of calorie restriction: VII. Topological rearrangement of hypothalamic aging networks

Derous, D., Mitchell, S. E., Green, C. L., Wang, Y., Chen, L., Promislow, D. E. L., Lusseau, D., Speakman, J. R. & Douglas, A., 23 Apr 2016, In : Aging. 8, 4, p. 917-931 16 p.

Research output: Contribution to journalArticle

Open Access
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8 Citations (Scopus)
9 Downloads (Pure)

The effects of graded levels of calorie restriction: VI. Impact of short-term graded calorie restriction on transcriptomic responses of the hypothalamic hunger and circadian signaling pathways

Derous, D., Mitchell, S. E., Green, C. L., Chen, L., Han, J-D. J., Wang, Y., Promislow, D. E. L., Lusseau, D., Speakman, J. R. & Douglas, A., Apr 2016, In : Aging. 8, 4, p. 642-661 20 p.

Research output: Contribution to journalArticle

Open Access
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15 Citations (Scopus)
12 Downloads (Pure)

The effects of graded levels of calorie restriction: XVI. Metabolomic changes in the cerebellum indicate activation of hypothalamocerebellar connections driven by hunger responses

Green, C. L., Mitchell, S. E., Derous, D., García-Flores, L. A., Wang, Y., Chen, L., Han, J-D. J., Promislow, D. E. L., Lusseau, D., Douglas, A. & Speakman, J. R., 14 Oct 2020, In : The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences.

Research output: Contribution to journalArticle

The effects of graded levels of calorie restriction: VIII. impact of short term calorie and protein restriction on basal metabolic rate in the C57BL/6 mouse

Mitchell, S. E., Tang, Z. H., Kerbois, C., Delville, C., Derous, D., Green, C. L., Wang, Y., Han, J. J. D., Chen, L., Douglas, A., Lusseau, D., Promislow, D. E. L. & Speakman, J. R., 2017, In : Oncotarget. 8, 11, p. 17453-17474 22 p.

Research output: Contribution to journalArticle

Open Access
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11 Citations (Scopus)
11 Downloads (Pure)

The effects of graded levels of calorie restriction: XI. Evaluation of the main hypotheses underpinning the life extension effects of CR using the hepatic transcriptome

Derous, D., Mitchell, S. E., Wang, L., Green, C. L., Wang, Y., Chen, L., Han, J-D. J., Promislow, D. E. L., Lusseau, D., Douglas, A. & Speakman, J. R., 31 Jul 2017, In : Aging. 9, 7, p. 1770-1824 55 p.

Research output: Contribution to journalArticle

Open Access
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14 Citations (Scopus)
22 Downloads (Pure)

The effects of graded levels of calorie restriction: IX. Global metabolomic screen reveals modulation of carnitines, sphingolipids and bile acids in the liver of C57BL/6 mice

Green, C. L., Mitchell, S. E., Derous, D., Wang, Y., Chen, L., Han, J-D. J., Promislow, D. E. L., Lusseau, D., Douglas, A. & Speakman, J. R., Jun 2017, In : Aging Cell. 16, 3, p. 529-540 12 p.

Research output: Contribution to journalArticle

Open Access
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24 Citations (Scopus)
8 Downloads (Pure)

The effects of graded levels of calorie restriction: V. Impact of short term calorie and protein restriction on physical activity in the C57BL/6 mouse

Mitchell, S. E., Delville, C., Konstantopedos, P., Derous, D., Green, C. L., Wang, Y., Han, J-D. J., Promislow, D. E. L., Douglas, A., Chen, L., Lusseau, D. & Speakman, J. R., 17 Mar 2016, In : Oncotarget. 7, 15, p. 19147-19170 24 p.

Research output: Contribution to journalArticle

Open Access
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19 Citations (Scopus)
9 Downloads (Pure)
Open Access
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3 Citations (Scopus)
2 Downloads (Pure)

The Effects of Graded Levels of Calorie Restriction: X. Transcriptomic Responses of Epididymal Adipose Tissue

Derous, D., Mitchell, S. E., Green, C. L., Wang, Y., Han, J. D. J., Chen, L., Promislow, D. E. L., Lusseau, D., Douglas, A. & Speakman, J. R., 2 Mar 2018, In : The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. 73, 3, p. 279-288 10 p.

Research output: Contribution to journalArticle

Open Access
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6 Citations (Scopus)
8 Downloads (Pure)