Mechanisms of Fish Oil-Modulated Inflammation and Health

B. de Roos*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Intake of fish, fish oil, and long-chain n-3 polyunsaturated fatty acids may help to prevent the development of chronic diseases such as coronary heart disease and cancer. Their anti-inflammatory properties are believed to play an important role in this beneficial effect. Long-chain n-3 polyunsaturated fatty acids modulate endothelial activation, eicosanoid metabolism (including epoxygenation pathways), and inflammatory resolution in vitro. Future studies should aim to elucidate novel biomarkers that can be applied to measure the efficacy of long-chain n-3 polyunsaturated fatty acids in relation to inflammation in vivo.
Original languageEnglish
Title of host publicationBioactive Food as Interventions for Arthritis and Related Inflammatory Diseases
EditorsRonald Ross Watson, Victor R. Preedy
PublisherElsevier Inc
Pages545-553
Number of pages9
ISBN (Print)9780123971562
DOIs
Publication statusPublished - 2013

Keywords

  • Biomarkers
  • Cancer
  • Cardiovascular disease
  • Eicosanoid metabolism
  • Endothelial activation
  • Fish
  • Fish oil
  • Inflammation
  • Inflammatory resolution
  • Long-chain n-3 polyunsaturated fatty acids

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  • Cite this

    de Roos, B. (2013). Mechanisms of Fish Oil-Modulated Inflammation and Health. In R. R. Watson, & V. R. Preedy (Eds.), Bioactive Food as Interventions for Arthritis and Related Inflammatory Diseases (pp. 545-553). [42] Elsevier Inc. https://doi.org/10.1016/B978-0-12-397156-2.00213-1