Mechanisms of Fish Oil-Modulated Inflammation and Health

B. de Roos

doi:10.1016/B978-0-12-397156-2.00213-1

Mechanisms of Fish Oil-Modulated Inflammation and Health

B. de Roos^*

^*Corresponding author for this work

The Rowett Institute of Nutrition and Health

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Citation (Scopus)

Abstract

Intake of fish, fish oil, and long-chain n-3 polyunsaturated fatty acids may help to prevent the development of chronic diseases such as coronary heart disease and cancer. Their anti-inflammatory properties are believed to play an important role in this beneficial effect. Long-chain n-3 polyunsaturated fatty acids modulate endothelial activation, eicosanoid metabolism (including epoxygenation pathways), and inflammatory resolution in vitro. Future studies should aim to elucidate novel biomarkers that can be applied to measure the efficacy of long-chain n-3 polyunsaturated fatty acids in relation to inflammation in vivo.

Original language	English
Title of host publication	Bioactive Food as Interventions for Arthritis and Related Inflammatory Diseases
Editors	Ronald Ross Watson, Victor R. Preedy
Publisher	Elsevier Inc
Pages	545-553
Number of pages	9
ISBN (Print)	9780123971562
DOIs	https://doi.org/10.1016/B978-0-12-397156-2.00213-1
Publication status	Published - 2013

Keywords

Biomarkers
Cancer
Cardiovascular disease
Eicosanoid metabolism
Endothelial activation
Fish
Fish oil
Inflammation
Inflammatory resolution
Long-chain n-3 polyunsaturated fatty acids

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/B978-0-12-397156-2.00213-1Licence: Unspecified

Cite this

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abstract = "Intake of fish, fish oil, and long-chain n-3 polyunsaturated fatty acids may help to prevent the development of chronic diseases such as coronary heart disease and cancer. Their anti-inflammatory properties are believed to play an important role in this beneficial effect. Long-chain n-3 polyunsaturated fatty acids modulate endothelial activation, eicosanoid metabolism (including epoxygenation pathways), and inflammatory resolution in vitro. Future studies should aim to elucidate novel biomarkers that can be applied to measure the efficacy of long-chain n-3 polyunsaturated fatty acids in relation to inflammation in vivo.",

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KW - Biomarkers

KW - Cancer

KW - Cardiovascular disease

KW - Eicosanoid metabolism

KW - Endothelial activation

KW - Fish

KW - Fish oil

KW - Inflammation

KW - Inflammatory resolution

KW - Long-chain n-3 polyunsaturated fatty acids

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M3 - Chapter

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SN - 9780123971562

SP - 545

EP - 553

BT - Bioactive Food as Interventions for Arthritis and Related Inflammatory Diseases

A2 - Watson, Ronald Ross

A2 - Preedy, Victor R.

PB - Elsevier Inc

ER -

Mechanisms of Fish Oil-Modulated Inflammation and Health

Abstract

Keywords

UN SDGs

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