Organization profile

Organisation profile

The mission of the Kosterlitz Centre for Therapeutics is to facilitate the translation of biological innovation into novel therapeutics and to provide unique opportunities for specialised training in biodiscovery. It capitalises on the wealth of biology expertise in the University of Aberdeen and represents the link between academics, industrial partners and the business sector.

Fingerprint Dive into the research topics where Kosterlitz Centre for Therapeutics is active. These topic labels come from the works of this organisation's members. Together they form a unique fingerprint.

rimonabant Chemical Compounds
Pyrazoles Chemical Compounds
Triazoles Chemical Compounds
Cannabinoid Receptor CB1 Chemical Compounds
Ligands Chemical Compounds
Phospholipase D Chemical Compounds
glutamates Physics & Astronomy
ligands Physics & Astronomy

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Research Output 2014 2018

  • 14 Citations
  • 4 Article
7 Downloads (Pure)

Preclinical Evaluation of [18F]LCATD as a PET Tracer to Study Drug-Drug Interactions Caused by Inhibition of Hepatic Transporters

Testa, A., Dall'Angelo, S., Mingarelli, M., Augello, A., Schweiger, L., Welch, A., Elmore, C. S., Dawson, D., Sharma, P. & Zanda, M., 30 Jul 2018, In : Contrast Media & Molecular Imaging. 2018, 10 p., 3064751.

Research output: Contribution to journalArticle

Open Access
File
Drug Interactions
Liver
Pharmaceutical Preparations
Fusidic Acid
Radioactivity
6 Citations (Scopus)
11 Downloads (Pure)

Tricyclic fused pyrazoles with a 'Click' 1,2,3-triazole substituent in position 3 are nanomolar CB1 receptor ligands

Zanato, C., Cascio, M. G., Lazzari, P., Pertwee, R., Testa, A. & Zanda, M., Mar 2015, In : Synthesis. 47, 6, p. 817-826 10 p.

Research output: Contribution to journalArticle

Open Access
File
Pyrazoles
Cannabinoid Receptor CB1
rimonabant
Triazoles
Chlorine
3 Citations (Scopus)

Pyrazoles with a "click" 4-[N-(4-fluorobutyl)-1,2,3-triazole] substituent in position 3 are nanomolar CB1 receptor ligands

Distinto, R., Zanato, C., Montanari, S., Cascio, M. G., Lazzari, P., Pertwee, R. & Zanda, M., Nov 2014, In : Journal of Fluorine Chemistry. 167, p. 184-191 8 p.

Research output: Contribution to journalArticle

rimonabant
Pyrazoles
Cannabinoid Receptor CB1
Triazoles
ligand