Organization profile

Organisation profile

Immune gene discovery

The Scottish Fish Immunology Research Centre has a strong research team dedicated to fish immune gene discovery and is committed to its leading research at the forefront of this field. Main interests include:

identification of novel immune genes and elucidation of their physiological functions in innate and acquired immune responses in fish:
Genetic markers for fish disease resistance;
pioneering new technologies such as microarrays for gene analysis in fish.
Leucocyte Biology

The fish immune system has evolved a wide range of defence mechanisms against pathogen invasion, which require different cell types that regulate innate and acquired immune responses. Cellular control of immune processes in fish is poorly understood and few leucocyte populations have been isolated and characterised. One of the research aims is to study the role(s) of lymphocyte subpopulations that mediate immune responses and to identify the immune factors that regulate leucocyte activation. These include:

identification of cell surface markers and isolation of leucocyte subpopulations by flow cytometry;
development of bioassays for cytokines and other immune factors.
Fish vaccine development

Vaccines have become one of the major approaches to combat fish diseases in recent years and have made a major contribution to improvements of fish health in aquaculture. The Scottish Fish Immunology Research Centre facilitates research on the development of novel effective vaccines, immunostimulants/adjuvants, and antiviral/antimicrobial reagents in fish. Recent studies have investigated the mechanisms of induced resistance of DNA vaccines, the use of cytokines as adjuvants and the potency of novel fish antimicrobial peptides.

Fingerprint Dive into the research topics where Scottish Fish Immunology Research Centre is active. These topic labels come from the works of this organisation's members. Together they form a unique fingerprint.

Fishes Medicine & Life Sciences
Oncorhynchus mykiss Medicine & Life Sciences
Salmo salar Medicine & Life Sciences
fish Agriculture & Biology
rainbow Earth & Environmental Sciences
Genes Medicine & Life Sciences
Trout Medicine & Life Sciences
gene Earth & Environmental Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1994 2020

Arginine, ornithine and citrulline supplementation in rainbow trout: free amino acid dynamics and gene expression responses to bacterial infection

Clark, T. C., Tinsley, J., Sigholt, T., MacQueen, D. J. & Martin, S. A. M., 22 Jan 2020, (Accepted/In press) In : Fish & Shellfish Immunology.

Research output: Contribution to journalArticle

bacterial infections

An insight into piscidins: The discovery, modulation and bioactivity of greater amberjack, Seriola dumerili, piscidin

Milne, D. J., Fernández-Montero, Á., Gundappa, M. K., Wang, T., Acosta, F., Torrecillas, S., Montero, D., Zou, J., Sweetman, J. & Secombes, C. J., Oct 2019, In : Molecular Immunology. 114, p. 378-388 11 p.

Research output: Contribution to journalArticle

Head Kidney
Poly I-C
1 Citation (Scopus)

Biological Concepts for the Control of Aquatic Zoosporic Diseases

Frenken, T., Agha, R., Schmeller, D. S., van West, P. & Wolinska, J., 1 Jul 2019, In : Trends in Parasitology. 35, 7, p. 571-582 12 p.

Research output: Contribution to journalArticle



Intercellular Interferons in Fish; A unique means to combat viral infection

Xian, C. M. (Creator), Zou, J. (Creator), Nie, P. (Creator), Huang, B. (Creator), Yu, Z. (Creator), Collet, B. (Creator), Secombes, C. (Creator), Figshare, 14 Nov 2013


Proteomic comparison of selective breeding and growth hormone transgenesis in fish

Causey, D. R. (Creator), Kim, J. (Creator), Stead, D. (Creator), Martin, S. (Creator), Devlin, R. H. (Creator), MacQueen, D. J. (Creator), Elsevier, 25 Aug 2018



Berkeley Award

Pieter van West (Recipient), 6 Dec 2002

Prize: Awards, Medals, Prizes and Distinctions


Fellow of the Scottish Crop Research Institute

Pieter van West (Recipient), 2006

Prize: National/international honour

Press / Media

Route parasite takes to infect fish uncovered

Pieter van West & Stephan Werner Wawra


1 item of Media coverage

Press/Media: Research