Organization profile

Organisation profile

Immune gene discovery

The Scottish Fish Immunology Research Centre has a strong research team dedicated to fish immune gene discovery and is committed to its leading research at the forefront of this field. Main interests include:

identification of novel immune genes and elucidation of their physiological functions in innate and acquired immune responses in fish:
Genetic markers for fish disease resistance;
pioneering new technologies such as microarrays for gene analysis in fish.
Leucocyte Biology


The fish immune system has evolved a wide range of defence mechanisms against pathogen invasion, which require different cell types that regulate innate and acquired immune responses. Cellular control of immune processes in fish is poorly understood and few leucocyte populations have been isolated and characterised. One of the research aims is to study the role(s) of lymphocyte subpopulations that mediate immune responses and to identify the immune factors that regulate leucocyte activation. These include:

identification of cell surface markers and isolation of leucocyte subpopulations by flow cytometry;
development of bioassays for cytokines and other immune factors.
Fish vaccine development


Vaccines have become one of the major approaches to combat fish diseases in recent years and have made a major contribution to improvements of fish health in aquaculture. The Scottish Fish Immunology Research Centre facilitates research on the development of novel effective vaccines, immunostimulants/adjuvants, and antiviral/antimicrobial reagents in fish. Recent studies have investigated the mechanisms of induced resistance of DNA vaccines, the use of cytokines as adjuvants and the potency of novel fish antimicrobial peptides.

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Fishes Medicine & Life Sciences
Oncorhynchus mykiss Medicine & Life Sciences
Salmo salar Medicine & Life Sciences
fish Agriculture & Biology
rainbow Earth & Environmental Sciences
Genes Medicine & Life Sciences
Trout Medicine & Life Sciences
Saprolegnia Medicine & Life Sciences

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Research Output 1999 2019

sodium arsenite
Chlorella vulgaris
Oreochromis niloticus
arsenites
dietary supplements
Receptors, Tumor Necrosis Factor, Type II
Receptors, Tumor Necrosis Factor, Type I
Tumor Necrosis Factor Receptors
Oncorhynchus mykiss
Fishes
5 Citations (Scopus)
4 Downloads (Pure)
Open Access
File
vaccination
rainbow
Oncorhynchus mykiss
cytokines
injection

Prizes

Berkeley Award

Pieter van West (Recipient), 6 Dec 2002

Prize: Prize (including medals and awards)

mycology

Fellow of the Scottish Crop Research Institute

Pieter van West (Recipient), 2006

Prize: National/international honour