Research output per year
Research output per year
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Dive into the research topics where David Horsley is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Assays for the Screening and Characterization of Tau Aggregation Inhibitors
Horsley, D., Rickard, J. E., Vorley, T., Leeper, M. F., Wischik, C. M. & Harrington, C. R., 24 Mar 2024, Tau Protein: Methods and Protocols. 2 ed. Vol. 2754. p. 93-104 12 p. (Methods in molecular biology (Clifton, N.J.); vol. 2754).Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review
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LETC inhibits α-Syn aggregation and ameliorates motor deficiencies in the L62 mouse model of synucleinopathy
Schwab, K., Frahm, S., Magbagbeolu, M., Horsley, D., Goatman, E., Melis, V., Theuring, F., Ishaq, A., Storey, J. M. D., Harrington, C., Wischik, C. & Riedel, G., 18 Mar 2024, (E-pub ahead of print) In: European Journal of Pharmacology. 50 p., 176505.Research output: Contribution to journal › Article › peer-review
Open Access -
Alpha-Synuclein transgenic mice, h-α-SynL62, display α-Syn aggregation and a dopaminergic phenotype reminiscent of Parkinson's disease
Frahm, S., Melis, V., Horsley, D., Rickard, J., Riedel, G., Fadda, P., Scherma, M., Harrington, C., Wischik, C., Theuring, F. & Schwab, K., 26 Feb 2018, In: Behavioural Brain Research. 339, p. 153-168 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile20 Citations (Scopus)35 Downloads (Pure) -
A Protein Aggregation Inhibitor, Leuco-Methylthioninium Bis(Hydromethanesulfonate), Decreases α-Synuclein Inclusions in a Transgenic Mouse Model of Synucleinopathy
Schwab, K., Frahm, S., Horsley, D., Rickard, J. E., Melis, V., Goatman, E. A., Magbagbeolu, M., Douglas, M., Leith, M. G., Baddeley, T. C., Storey, J. M. D., Riedel, G., Wischik, C. M., Harrington, C. R. & Theuring, F., 10 Jan 2018, In: Frontiers in Molecular Neuroscience. 10, 15 p., 447.Research output: Contribution to journal › Article › peer-review
Open AccessFile24 Citations (Scopus)18 Downloads (Pure) -
Assays for the Screening and Characterization of Tau Aggregation Inhibitors
Rickard, J. E., Horsley, D., Wischik, C. M. & Harrington, C. R., 15 Dec 2016, Tau Protein: Methods and Protocols. Smet-Nocca, C. (ed.). Springer , Vol. 1523. p. 129-140 12 p. (Methods in Molecular Biology; vol. 1523).Research output: Chapter in Book/Report/Conference proceeding › Chapter
4 Citations (Scopus)
Impacts
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Discovery and commercialisation of an entirely new drug for the treatment of Alzheimer's disease
Claude Wischik (Participant), Charles Harrington (Participant), John Storey (Participant), Janet Rickard (Participant), David Horsley (Participant), Thomas Baddeley (Participant), Steven Kemp (Participant), James Sinclair (Participant), Claudia Zabke (Participant), F. Theuring (Participant), F Stamer (Participant) & C Marshall (Participant)
Impact: Health and Wellbeing, Economic and/or Commercial
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Discovery and development of a new drug for the treatment of dementia
Claude Wischik (Coordinator), Charles Harrington (Coordinator), John Storey (Participant), Janet Rickard (Participant) & David Horsley (Participant)
Impact: Economic and/or Commercial