• Polwarth Building, Foresterhill, Aberdeen

      United Kingdom

    • 162 Citations
    20022018
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    Fingerprint Dive into the research topics where David Horsley is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

    • 16 Similar Profiles
    Tauopathies Medicine & Life Sciences
    Alzheimer Disease Medicine & Life Sciences
    Transgenic Mice Medicine & Life Sciences
    Synucleins Medicine & Life Sciences
    tau Proteins Chemical Compounds
    Salts Chemical Compounds
    Parkinson Disease Medicine & Life Sciences
    Methylene Blue Medicine & Life Sciences

    Network Recent external collaboration on country level. Dive into details by clicking on the dots.

    Research Output 2002 2018

    7 Citations (Scopus)
    19 Downloads (Pure)

    Alpha-Synuclein transgenic mice, h-α-SynL62, display α-Syn aggregation and a dopaminergic phenotype reminiscent of Parkinson's disease

    Frahm, S., Melis, V., Horsley, D., Rickard, J. E., Riedel, G., Fadda, P., Scherma, M., Harrington, C. R., Wischik, C. M., Theuring, F. & Schwab, K., 26 Feb 2018, In : Behavioural Brain Research. 339, p. 153-168 16 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    alpha-Synuclein
    Transgenic Mice
    Parkinson Disease
    Lewy Body Disease
    Amphetamine
    3 Citations (Scopus)
    11 Downloads (Pure)
    Open Access
    File
    Synucleins
    Transgenic Mice
    Proteins
    Parkinson Disease
    Endopeptidase K
    2 Citations (Scopus)

    Assays for the Screening and Characterization of Tau Aggregation Inhibitors

    Rickard, J. E., Horsley, D., Wischik, C. M. & Harrington, C. R., 15 Dec 2016, Tau Protein: Methods and Protocols. Smet-Nocca, C. (ed.). Springer , Vol. 1523. p. 129-140 12 p. (Methods in Molecular Biology; vol. 1523).

    Research output: Chapter in Book/Report/Conference proceedingChapter

    tau Proteins
    Tauopathies
    Immunoassay
    Recombinant Proteins
    Alzheimer Disease
    42 Citations (Scopus)
    5 Downloads (Pure)
    Open Access
    File
    Proteolysis
    Alzheimer Disease
    Agglomeration
    Brain
    Salts
    55 Citations (Scopus)
    Oxidation-Reduction
    Stomach
    Alzheimer Disease
    Aptitude
    Methylene Blue

    Impacts

    Discovery and commercialisation of an entirely new drug for the treatment of Alzheimer's disease

    Claude Wischik (Participant), Charles Harrington (Participant), John Storey (Participant), Janet Rickard (Participant), David Horsley (Participant), Thomas Baddeley (Participant), Steven Kemp (Participant), James Sinclair (Participant), Claudia Zabke (Participant), F. Theuring (Participant), F Stamer (Participant), C Marshall (Participant)

    Impact: Quality of life Impacts, Economic Impacts