Research output per year
Research output per year
- 1 - 50 out of 100 results
Search results
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2024
Accraspiroketides A-B, Phenylnaphthacenoid-Derived Polyketides with Unprecedented [6+6+6+6]+[5+5] Spiro-Architecture
Maglangit, F., Wang, S., Moser, A., Kyeremeh, K., Trembleau, L., Zhou, Y., Clark, D. J., Tabudravu, J. & Deng, H., 29 Mar 2024, (E-pub ahead of print) In: Journal of Natural Products.Research output: Contribution to journal › Article › peer-review
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Size matters
Su, L. & Deng, H., Jan 2024, In: Nature Chemical Biology. 20, p. 8-10 3 p.Research output: Contribution to journal › Comment/debate › peer-review
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2023
Dehydroamino acid residues in bioactive natural products
Wang, S., Wu, K., Tang, Y-J. & Deng, H., 9 Nov 2023, (E-pub ahead of print) In: Natural Product Reports.Research output: Contribution to journal › Review article › peer-review
Open AccessFile1 Citation (Scopus) -
3'-O-β-Glucosyl-4',5'-didehydro-5'-deoxyadenosine Is a Natural Product of the Nucleocidin Producers Streptomyces virens and Streptomyces calvus.
Feng, X., Zhang, Q., Clarke, D. J., Deng, H. & O'Hagan, D., 27 Oct 2023, In: Journal of Natural Products. 86, 10, p. 2326-2332 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Downloads (Pure) -
Exploring a Streptomyces wax synthase using acyl-SNACs as donor substrates
Casolari, F., Alrashdi, S., Carr, R. & Deng, H., 1 Oct 2023, In: RSC Chemical Biology. 4, 10, p. 742-747 6 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Biosynthesis of trialkyl-substituted aromatic polyketide NFAT-133 involves unusual P450 monooxygenase-mediating aromatization and a putative metallo-beta-lactamase fold hydrolase
Yang, M., Li, W., Zhou, L., Lin, X., Zhang, W., Shen, Y., Deng, H., Lin, H-W. & Zhou, Y., 1 Sept 2023, In: Synthetic and Systems Biotechnology. 8, 3, p. 349-356 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus) -
Deletion of the accramycin pathway-specific regulatory gene accJ activates the production of unrelated polyketide metabolites
Maglangit, F., Kyeremeh, K. & Deng, H., 1 Aug 2023, In: Natural Product Research. 37, 16, p. 2753-2758 6 p.Research output: Contribution to journal › Article › peer-review
4 Citations (Scopus) -
Identification of genes essential for fluorination and sulfamylation within the nucleocidin gene clusters of Streptomyces calvus and Streptomyces virens
Wojnowska, M., Feng, X., Chen, Y., Deng, H. & O'Hagan, D., 1 Mar 2023, In: ChemBioChem. 24, 5, 9 p., e202200684.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)1 Downloads (Pure) -
Switching Prenyl Donor Specificities in Squalene Synthase-Like Aromatic Prenyltransferases from Bacterial Carbazole Alkaloid Biosynthesis
Shen, Y., Zhang, L., Yang, M., Shi, T., Li, Y., Li, L., Yu, Y., Deng, H., Lin, H. W. & Zhou, Y., 20 Jan 2023, In: ACS Chemical Biology. 18, 1, p. 123-133 11 p.Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus) -
Chemoenzymatic Synthesis of Indole-Containing Acyloin Derivatives
Alrashdi, S., Casolari, F., Alabed, A., Kyeremeh, K. & Deng, H., 1 Jan 2023, In: Molecules. 28, 10 p., 354.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)17 Downloads (Pure) -
2022
Digyalipopeptide A, an antiparasitic cyclic peptide from the Ghanaian Bacillus sp. strain DE2B.
Nartey, A. P., Dofuor, A. K., Owusu, K. B. A., Camas, A. S., Deng, H., Jaspars, M. & Kyeremeh, K., 28 Dec 2022, In: Beilstein journal of organic chemistry. 18, p. 1763-1771 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Downloads (Pure) -
A ribosomally synthesised and post-translationally modified peptide containing a β-enamino acid and a macrocyclic motif
Wang, S., Lin, S., Fang, Q., Gyampoh, R., Lu, Z., Gao, Y., Clarke, D. J., Wu, K., Trembleau, L., Yu, Y., Kyeremeh, K., Milne, B. F., Tabudravu, J. & Deng, H., 26 Aug 2022, In: Nature Communications. 13, 1, 15 p., 5044.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Citations (Scopus)1 Downloads (Pure) -
A Second Near-Infrared Ru(II) Polypyridyl Complex for Synergistic Chemo-Photothermal Therapy
Liu, Y., Li, Q., Gu, M., Lu, D., Xiong, X., Zhang, Z., Pan, Y., Liao, Y., Ding, Q., Gong, W., Chen, D. S., Guan, M., Wu, J., Tian, Z., Deng, H., Gu, L., Hong, X. & Xiao, Y., 10 Feb 2022, In: Journal of Medicinal Chemistry. 65, 3, p. 2225-2237 13 p.Research output: Contribution to journal › Article › peer-review
34 Citations (Scopus) -
Organic NIR-II dyes with ultralong circulation persistence for image-guided delivery and therapy
Li, Y., Gao, J., Wang, S., Li, S., Hou, X., Pan, Y., Gao, J., Qiao, X., Tian, Z., Chen, D., Deng, H., Deng, Z., Hong, X. & Xiao, Y., 1 Feb 2022, In: Journal of Controlled Release. 342, p. 157-169 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile28 Citations (Scopus)6 Downloads (Pure) -
Aminoacyl chain translocation catalysed by a type II thioesterase domain in an unusual non-ribosomal peptide synthetase
Wang, S., Brittain, W. D. G., Zhang, Q., Lu, Z., Tong, M. H., Wu, K., Kyeremeh, K., Jenner, M., Yu, Y., Cobb, S. L. & Deng, H., 10 Jan 2022, In: Nature Communications. 13, 1, 14 p., 62.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Citations (Scopus)4 Downloads (Pure) -
Characterization of a class II ketol-acid reductoisomerase from Mycobacterium tuberculosis
Valera, A., Wang, S., Carr, R., Trembleau, L. & Deng, H., 2022, In: RSC Advances. 12, 17, p. 10540-10544 5 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Downloads (Pure) -
2021
The chemical profile of activated secondary metabolites by overexpressing LaeA in Aspergillus niger
Wang, B., Li, X., Tabudravu, J., Wang, S., Deng, H. & Pan, L., Jul 2021, In: Microbiological Research. 248, 6 p., 126735.Research output: Contribution to journal › Article › peer-review
4 Citations (Scopus) -
Peculiarities of promiscuous l-threonine transaldolases for enantioselective synthesis of β-hydroxy-α-amino acids
Deng, H. & Wang, S., 1 May 2021, In: Applied Microbiology and Biotechnology. 105, p. 3507–3520 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)4 Downloads (Pure) -
Bacterial Pathogens: Threat or Treat? (a review on bioactive natural products from bacterial pathogens)
Maglangit, F., Yu, Y. & Deng, H., 1 Apr 2021, In: Natural Product Reports. 38, 4, p. 782-821 40 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile34 Citations (Scopus)10 Downloads (Pure) -
Genomic scanning enabling discovery of a new antibacterial bicyclic carbamate-containing alkaloid
Fang, Q., Wu, L., Urwald, C., Mugat, M., Wang, S., Kyeremeh, K., Philips, C., Law, S., Zhou, Y. & Deng, H., Mar 2021, In: Synthetic and Systems Biotechnology. 6, 1, p. 12-19 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)5 Downloads (Pure) -
Discovery and biosynthetic investigation of a new antibacterial dehydrated non‐ribosomal tripeptide
Wang, S., Fang, Q., Lu, Z., Gao, Y., Trembleau, L., Ebel, R., Andersen, J. H., Philips, C., Law, S. & Deng, H., 8 Feb 2021, In: Angewandte Chemie International Edition. 60, 6, p. 3229-3237 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile24 Citations (Scopus)6 Downloads (Pure) -
2020
Upconversion NIR-II fluorophores for mitochondria-targeted cancer imaging and photothermal therapy
Zhou, H., Zeng, X., Li, A., Zhou, W., Tang, L., Hu, W., Fan, Q., Meng, X., Deng, H., Duan, L., Li, Y., Deng, Z., Hong, X. & Xiao, Y., 3 Dec 2020, In: Nature Communications. 11, 14 p., 6183.Research output: Contribution to journal › Article › peer-review
Open AccessFile176 Citations (Scopus)6 Downloads (Pure) -
Discovery of New Antibacterial Accramycins from a Genetic Variant of the Soil Bacterium, Streptomyces sp. MA37
Maglangit, F., Zhang, Y., Kyeremeh, K. & Deng, H., 20 Oct 2020, In: Biomolecules. 10, 10, p. 1-11 11 p., 1464.Research output: Contribution to journal › Article › peer-review
Open AccessFile12 Citations (Scopus)2 Downloads (Pure) -
Defluorination of 4-fluorothreonine by threonine deaminase
Wu, L. & Deng, H., 28 Aug 2020, In: Organic & Biomolecular Chemistry. 18, 32, p. 6236-6240 5 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)4 Downloads (Pure) -
Identification of 5-Fluoro-5-Deoxy-Ribulose as a Shunt Fluorometabolite in Streptomyces sp. MA37
Wu, L., Tong, M. H., Kyeremeh, K. & Deng, H., 10 Jul 2020, In: Biomolecules. 10, 7, 11 p., 1023.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)3 Downloads (Pure) -
Novel South African Rare Actinomycete Kribbellaspeibonae Strain SK5: A Prolific Producer of Hydroxamate Siderophores Including New Dehydroxylated Congeners
Acquah, K. S., Beukes, D. R., Warner, D. F., Meyers, P. R., Sunassee, S. N., Maglangit, F., Deng, H., Jaspars, M. & Gammon, D. W., 29 Jun 2020, In: Molecules. 25, 13, 12 p., 2979.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Citations (Scopus)4 Downloads (Pure) -
An unusual metal-bound 4-fluorothreonine transaldolase from Streptomyces sp. MA37 catalyses promiscuous transaldol reactions
Wu, L., Tong, M. H., Raab, A., Fang, Q., Wang, S., Kyeremeh, K., Yu, Y. & Deng, H., 1 May 2020, In: Applied Microbiology and Biotechnology. 104, p. 3885-3896 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile17 Citations (Scopus)3 Downloads (Pure) -
Fluorine biocatalysis
Wu, L., Maglangit, F. & Deng, H., Apr 2020, In: Current Opinion in Chemical Biology. 55, p. 119-126 6 p.Research output: Contribution to journal › Article › peer-review
35 Citations (Scopus) -
Characterization of the promiscuous N-acyl CoA transferase, LgoC, in legonoxamine biosynthesis
Maglangit, F., Alrashdi, S., Renault, J., Trembleau, L., Victoria, C., Tong, M. H., Wang, S., Kyeremeh, K. & Deng, H., 28 Mar 2020, In: Organic & Biomolecular Chemistry. 18, 12, p. 2219-2222 4 p.Research output: Contribution to journal › Article › peer-review
8 Citations (Scopus) -
Novel NIR-II organic fluorophores for bioimaging beyond 1550 nm
Li, Y., Liu, Y., Li, Q., Tian, T., Zhou, W., Cui, Y., Wang, X., cheng, X., Ding, Q., Wang, X., Wu, J., Deng, H., Li, Y., Meng, X., Deng, Z., Hong, X. & Xiao, Y., 14 Mar 2020, In: Chemical Science. 11, 10, p. 2621-2626 6 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile138 Citations (Scopus)8 Downloads (Pure) -
Targeted isolation of indole alkaloids from Streptomyces sp. CT37
Fang, Q., Maglangit, F., Mugat, M., Urwald, C., Kyeremeh, K. & Deng, H., Mar 2020, In: Molecules. 25, 5, 10 p., 1108.Research output: Contribution to journal › Article › peer-review
Open AccessFile13 Citations (Scopus)3 Downloads (Pure) -
The X-factor: enhanced β-oxidation on intracellular triacylglycerols enabling overproduction of polyketide drug-like molecules in microorganisms
Wang, S. & Deng, H., Mar 2020, In: Synthetic and Systems Biotechnology. 5, 1, p. 19-20 2 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)7 Downloads (Pure) -
Signalling and Bioactive Metabolites from Streptomyces sp. RK44
Fang, Q., Maglangit, F., Wu, L., Ebel, R., Kyeremeh, K., Andersen, J. H., Annang, F., Perez de Nanclares, G., Reyes, F. & Deng, H., 22 Jan 2020, In: Molecules. 25, 3, 13 p., 460.Research output: Contribution to journal › Article › peer-review
Open AccessFile15 Citations (Scopus)7 Downloads (Pure) -
A Co-Culturing Approach Enables Discovery and Biosynthesis of a Bioactive Indole Alkaloid Metabolite
Maglangit, F., Fang, Q., Kyeremeh, K., Sternberg, J. M., Ebel, R. & Deng, H., 8 Jan 2020, In: Molecules. 25, 2, 16 p., 256.Research output: Contribution to journal › Article › peer-review
Open AccessFile30 Citations (Scopus)4 Downloads (Pure) -
MS Dereplication for Rapid Discovery of Structurally New or Novel Natural Products
Tabudravu, J., Pellissier, L., Smith, A. J., Kid, R., Milton, E. J., Deng, H., Ebel, R., Gissi, C., Milne, B. F., Cimpan, G. & Jaspars, M., 6 Jan 2020, In: Marine Drugs. 18, 40, p. 56-57 2 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Citations (Scopus) -
2019
Enzymatic Reconstitution and Biosynthetic Investigation of the Bacterial Carbazole Neocarazostatin A
Liu, Y., Su, L., Fang, Q., Tabudravu, J., Yang, X., Rickaby, K., Trembleau, L., Kyeremeh, K., Deng, Z., Deng, H. & Yu, Y., 20 Dec 2019, In: Journal of Organic Chemistry. 84, 24, p. 16323-16328 6 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Citations (Scopus)5 Downloads (Pure) -
Paenidigyamycin g: 1-acetyl-2,4-dimethyl-3-phenethyl-1H-imidazol-3-ium
Tetevi, G. M., Kwain, S., Mensah, T., Camas, A. S., Camas, M., Dofuor, A. K., Azerigyik, F. A., Oluwabusola, E., Deng, H., Jaspars, M. & Kyeremeh, K., 21 Nov 2019, In: MolBank. 2019, 4, 9 p., M1094.Research output: Contribution to journal › Comment/debate › peer-review
Open AccessFile3 Citations (Scopus)6 Downloads (Pure) -
Accramycin A, a New Aromatic Polyketide, from the Soil Bacterium, Streptomyces sp. MA37
Maglangit, F., Fang, Q., Leman, V., Soldatou, S., Ebel, R., Kyeremeh, K. & Deng, H., 17 Sept 2019, In: Molecules. 24, 18, 3384.Research output: Contribution to journal › Article › peer-review
Open AccessFile30 Citations (Scopus)14 Downloads (Pure) -
Digyaindoleacid A: 2-(1-(4-hydroxyphenyl)-3-oxobut-1-en-2-yloxy)-3-(1H-indol-3-yl)propanoic acid, a novel indole alkaloid
Kwain, S., Tetevi, G. M., Mensah, T., Camas, A. S., Camas, M., Dofuor, A. K., Azerigyik, F. A., Deng, H., Jaspars, M. & Kyeremeh, K., 14 Sept 2019, In: MolBank. 2019, 3, 10 p., M1080.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus) -
Mn-Loaded apolactoferrin dots for in vivo MRI and NIR-II cancer imaging
Zhou, H., Yang, H., Tang, L., Wang, Y., Li, Y., Liu, N., Zeng, X., Yan, Y., Wu, J., Chen, S., Xiao, L., Yu, Y., Deng, Z., Deng, H., Hong, X. & Xiao, Y., 21 Aug 2019, In: Journal of Materials Chemistry A. 7, 31, p. 9448-9454 7 p.Research output: Contribution to journal › Article › peer-review
30 Citations (Scopus) -
α-D-glucopyranosyl-(1→2)-[6-O-(L-tryptophanyl)-β-D-fructofuranoside]
Kyeremeh, K., Kwain, S., Tetevi, G. M., Camas, A. S., Camas, M., Dofuor, A. K., Deng, H. & Jaspars, M., 16 Jun 2019, In: MolBank. 2019, 2, 11 p., M1066.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)8 Downloads (Pure) -
Investigation of Penicillin Binding Protein (PBP)-like Peptide Cyclase and Hydrolase in Surugamide Non-ribosomal Peptide Biosynthesis
Zhou, Y., Lin, X., Xu, C., Shen, Y., Wang, S-P., Liao, H., Li, L., Deng, H. & Lin, H-W., 16 May 2019, In: Cell chemical biology. 26, 5, p. 737-744 8 p.Research output: Contribution to journal › Article › peer-review
23 Citations (Scopus) -
Novel electrochemical nanoswitch biosensor based on self-assembled pH-sensitive continuous circular DNA
Chen, X., Yao, L., Wang, Y. C., Chen, Q., Deng, H., Lin, Z. Y. & Yang, H. H., 15 Apr 2019, In: Biosensors and Bioelectronics. 131, p. 274-279 6 p.Research output: Contribution to journal › Article › peer-review
13 Citations (Scopus) -
A novel near-infrared fluorescent light-up probe for tumor imaging and drug-induced liver injury detection
Zeng, X., Chen, Z., Tang, L., Yang, H., Liu, N., Zhou, H., Li, Y., Wu, J., Deng, Z., Yu, Y., Deng, H., Hong, X. & Xiao, Y., 28 Feb 2019, In: Chemical Communications. 55, 17, p. 2541-2544 4 p.Research output: Contribution to journal › Article › peer-review
33 Citations (Scopus) -
In vitro reconstitution of the biosynthetic pathway of 3-hydroxypicolinic acid
Yun, X., Zhang, Q., Lv, M., Deng, H., Deng, Z. & Yu, Y., 21 Jan 2019, In: Organic & Biomolecular Chemistry. 17, 3, p. 454-460 7 p.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
Legonoxamines A-B, two new hydroxamate siderophores from the soil bacterium, Streptomyces sp. MA37
Maglangit, F., Tong, M. H., Jaspars, M., Kyeremeh, K. & Deng, H., 3 Jan 2019, In: Tetrahedron Letters. 60, 1, p. 75-79 5 p.Research output: Contribution to journal › Article › peer-review
23 Citations (Scopus) -
LC-HRMS-Database Screening Metrics for Rapid Prioritization of Samples to Accelerate the Discovery of Structurally New Natural Products
Tabudravu, J. N., Pellissier, L., Smith, A. J., Subko, K., Autréau, C., Feussner, K., Hardy, D., Butler, D., Kidd, R., Milton, E. J., Deng, H., Ebel, R., Salonna, M., Gissi, C., Montesanto, F., Kelly, S. M., Milne, B. F., Cimpan, G. & Jaspars, M., 2019, In: Journal of Natural Products. 82, 2, p. 211-220 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile20 Citations (Scopus)7 Downloads (Pure) -
2018
Deletion of the epigenetic regulator GcnE in Aspergillus niger FGSC A1279 activates the production of multiple polyketide metabolites
Wang, B., Li, X., Yu, D., Chen, X., Tabudravu, J., Deng, H. & Pan, L., 31 Dec 2018, In: Microbiological Research. 217, p. 101-107 7 p.Research output: Contribution to journal › Article › peer-review
16 Citations (Scopus) -
Paenidigyamycin A, Potent Antiparasitic Imidazole Alkaloid from the Ghanaian Paenibacillus sp. DE2SH
Osei, E., Kwain, S., Mawuli, G. T., Anang, A. K., Owusu, K. B-A., Camas, M., Camas, A. S., Ohashi, M., Alexandru-Crivac, C-N., Deng, H., Jaspars, M. & Kyeremeh, K., 24 Dec 2018, In: Marine Drugs. 17, 1, 9.Research output: Contribution to journal › Article › peer-review
Open AccessFile25 Citations (Scopus)9 Downloads (Pure) -
Directed Accumulation of Anticancer Depsipeptides by Characterization of Neoantimycins Biosynthetic Pathway and an NADPH-Dependent Reductase
Zhou, Y., Lin, X., Williams, S. R., Liu, L., Shen, Y., Wang, S-P., Sun, F., Xu, S., Deng, H., Leadlay, P. F. & Lin, H-W., 17 Aug 2018, In: ACS Chemical Biology. 13, 8, p. 2153-2160 8 p.Research output: Contribution to journal › Article › peer-review
15 Citations (Scopus)