Michael Simpson

Dr

    • AB24 3UE

    • 104 Citations
    20022018
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    • 15 Similar Profiles
    Alzheimer Disease Medicine & Life Sciences
    biotin Physics & Astronomy
    tau Proteins Medicine & Life Sciences
    marking Physics & Astronomy
    Agglomeration Chemical Compounds
    Proteolysis Chemical Compounds
    Amination Chemical Compounds
    Dendrimers Chemical Compounds

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    Research Output 2002 2018

    • 104 Citations
    • 9 Article
    • 1 Patent
    1 Citation (Scopus)
    7 Downloads (Pure)

    Cysteine-independent inhibition of Alzheimer's disease-like paired helical filament assembly by leuco-methylthioninium (LMT)

    Al-Hilaly, Y. K., Pollack, S. J., Rickard, J. E., Simpson, M., Raulin, A-C., Baddeley, T., Schellenberger, P., Storey, J. M. D., Harrington, C. R., Wischik, C. M. & Serpell, L. C., 19 Oct 2018, In : Journal of Molecular Biology. 430, 21, p. 4119-4131 13 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    Cysteine
    Alzheimer Disease
    Tauopathies
    tau Proteins
    Neurofibrillary Tangles
    7 Citations (Scopus)
    13 Downloads (Pure)

    Alzheimer's Disease-like Paired Helical Filament Assembly from Truncated Tau Protein Is Independent of Disulfide Crosslinking

    Al-Hilaly, Y. K., Pollack, S. J., Vadukul, D., Citossi, F., Rickard, J. E., Simpson, M., Storey, J. M. D., Harrington, C. R., Wischik, C. M. & Serpell, L. C., 24 Nov 2017, In : Journal of Molecular Biology. 429, 23, p. 3650-3665 16 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    tau Proteins
    Disulfides
    Alzheimer Disease
    Amyloidogenic Proteins
    Neurofibrillary Tangles
    37 Citations (Scopus)
    5 Downloads (Pure)
    Open Access
    File
    Proteolysis
    Alzheimer Disease
    Agglomeration
    Brain
    Salts
    7 Citations (Scopus)
    File
    biotin
    Labeling
    Polyethylene glycols
    marking
    Cells
    11 Citations (Scopus)

    Development of 18F-fluorinatable dendrons and their application to cancer cell targeting

    Trembleau, L., Simpson, M., Cheyne, R. W., Escofet, I., Appleyard, M. V. C. L., Murray, K., Sharp, S., Thompson, A. M. & Smith, T. A. D., Nov 2011, In : New Journal of Chemistry. 35, 11, p. 2496-2502 7 p.

    Research output: Contribution to journalArticle

    Dendrimers
    Cells
    Biotin
    Avidin
    Sulfhydryl Compounds