• 5675 Citations
20002020

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Article
2000

Retinoids in embryonal development

Ross, S. A., McCaffery, P. J., Drager, U. C. & De Luca, L. M., Jul 2000, In : Physiological Reviews. 80, 3, p. 1021-1054 34 p.

Research output: Contribution to journalArticle

658 Citations (Scopus)
2001

Expression and regulation of the retinoic acid synthetic enzyme RALDH-2 in the embryonic chicken wing

Berggren, K., Ezerman, E. B., McCaffery, P. & Forehand, C. J., 2001, In : Developmental Dynamics. 222, 1, p. 1-16 16 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Retinoic acid synthesis for the developing telencephalon

Smith, D., Wagner, E., Koul, O., McCaffery, P. & Dräger, U. C., Oct 2001, In : Cerebral Cortex. 11, 10, p. 894-905 12 p.

Research output: Contribution to journalArticle

72 Citations (Scopus)
31 Citations (Scopus)

The distribution of retinaldehyde dehydrogenase-2 in rat and human orodental tissues

Berkovitz, B. K., Maden, M., McCaffery, P. J. A. & Barrett, A. W., 1 Dec 2001, In : Archives of Oral Biology. 46, 12, p. 1099-104 6 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2002

Retinoid quantification by HPLC/MS(n)

McCaffery, P., Evans, J., Koul, O., Volpert, A., Reid, K. & Ullman, M. D., 2002, In : Journal of Lipid Research. 43, 7, p. 1143-9 7 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)
2003

A critical period for retinoic acid teratogenesis and loss of neurophilic migration of pontine nuclei neurons

Yamamoto, M., Zhang, J., Smith, D., Hayakawa, Y. & McCaffery, P., 2003, In : Mechanisms of Development. 120, 6, p. 701-709 9 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Activation of retinoic acid signalling after sciatic nerve injury: up-regulation of cellular retinoid binding proteins

Zhelyaznik, N., Schrage, K., McCaffery, P. & Mey, J., 2003, In : European Journal of Neuroscience. 18, 5, p. 1033-1040 8 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)

The meninges is a source of retinoic acid for the late-developing hindbrain

Zhang, J., Smith, D., Yamamoto, M., Ma, L. & McCaffery, P., Aug 2003, In : Journal of Neuroscience. 23, 20, p. 7610-7620 11 p.

Research output: Contribution to journalArticle

56 Citations (Scopus)

Too much of a good thing: retinoic acid as an endogenous regulator of neural differentiation and exogenous teratogen

McCaffery, P. J., Adams, J., Maden, M. & Rosa-Molinar, E., Aug 2003, In : European Journal of Neuroscience. 18, 3, p. 457-472 16 p.

Research output: Contribution to journalArticle

144 Citations (Scopus)
2004

13-cis Retinoic acid (accutane) suppresses hippocampal cell survival in mice

Sakai, Y., Crandall, J. E., Brodsky, J. & McCaffery, P., 2004, In : Annals of the New York Academy of Sciences. 1021, p. 436-440 5 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)

13-cis-retinoic acid suppresses hippocampal cell division and hippocampal-dependent learning in mice

Crandall, J., Sakai, Y., Zhang, J., Koul, O., Mineur, Y., Crusio, W. E. & McCaffery, P., Apr 2004, In : PNAS. 101, 14, p. 5111-5116 6 p.

Research output: Contribution to journalArticle

172 Citations (Scopus)

CYP26A1 and CYP26C1 cooperate in degrading retinoic acid within the equatorial retina during later eye development

Sakai, Y., Luo, T., McCaffery, P. J. A., Hamada, H. & Dräger, U. C., 1 Dec 2004, In : Developmental Biology. 276, 1, p. 143-157 15 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)
46 Citations (Scopus)

Ethanol increases retinoic acid production in cerebellar astrocytes and in cerebellum

McCaffery, P. J. A., Koul, O., Smith, D., Napoli, J. L., Chen, N. & Ullman, M. D., 25 Nov 2004, In : Developmental Brain Research. 153, 2, p. 233-241 9 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Retinoic acid signaling in the nervous system of adult vertebrates

Mey, J. & McCaffery, P. J. A., Oct 2004, In : The Neuroscientist. 10, 5, p. 409-421 13 p.

Research output: Contribution to journalArticle

107 Citations (Scopus)
2005

Identification, expression analysis, genomic organization and cellular location of a novel protein with a RhoGEF domain

Tse, S-W., Broderick, J. A., Wei, M-L., Luo, M-H., Smith, D., McCaffery, P. J. A., Stamm, S. & Andreadis, A., 10 Oct 2005, In : Gene. 359, p. 63-72 10 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Macrocephaly and the control of brain growth in autistic disorders

McCaffery, P. J. A. & Deutsch, C. K., Sep 2005, In : Progress in Neurobiology. 77, 1-2, p. 38-56 19 p.

Research output: Contribution to journalArticle

65 Citations (Scopus)

Retinaldehyde dehydrogenase 2 and HoxC8 are required in the murine brachial spinal cord for the specification of Lim1+ motoneurons, and the correct distribution of Islet1+ motoneurons

Vermot, J., Schuhbaur, B., Le Mouellic, H., McCaffery, P. J. A., Garnier, J-M., Hentsch, D., Brûlet, P., Niederreither, K., Chambon, P., Dollé, P. & Le Roux, I., Apr 2005, In : Development. 132, 7, p. 1611-1621 11 p.

Research output: Contribution to journalArticle

59 Citations (Scopus)

Retinoic acid influences the development of the inferior olivary nucleus in the rodent

Yamamoto, M., Fujinuma, M., Hirano, S., Hayakawa, Y., Clagett-Dame, M., Zhang, J. & McCaffery, P. J. A., 15 Apr 2005, In : Developmental Biology. 280, 2, p. 421-433 13 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Retinoic acid synthesis by a population of NG2-positive cells in the injured spinal cord

Mey, J., J Morassutti, D., Brook, G., Liu, R-H., Zhang, Y-P., Koopmans, G. & McCaffery, P., 2005, In : European Journal of Neuroscience. 21, 6, p. 1555-1568 14 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)
2006

Defects in tangential neuronal migration of pontine nuclei neurons in the Largemyd mouse are associated with stalled migration in the ventrolateral hindbrain

Qu, Q., Crandall, J. E., Luo, T., McCaffery, P. J. & Smith, F. I., 1 Jun 2006, In : European Journal of Neuroscience. 23, 11, p. 2877-2886 10 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Retinoic acid signaling and function in the adult hippocampus

McCaffery, P., Zhang, J. & Crandall, J. E., Jun 2006, In : Journal of Neurobiology. 66, 7, p. 780-791 12 p.

Research output: Contribution to journalArticle

119 Citations (Scopus)
2007

Characterization of retinaldehyde dehydrogenase-2 induction in NG2-positive glia after spinal cord contusion injury

Kern, J., Schrage, K., Koopmans, G. C., Joosten, E. A., McCaffery, P. & Mey, J., Feb 2007, In : International Journal of Developmental Neuroscience. 25, 1, p. 7-16 10 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2008

Genome-wide identification of Smad/Foxh1 targets reveals a role for Foxh1 in retinoic acid regulation and forebrain development

Silvestri, C., Narimatsu, M., von Both, I., Liu, Y., Tan, N. B. J., Izzi, L., McCaffery, P., Wrana, J. L. & Attisano, L., 11 Mar 2008, In : Developmental Cell. 14, 3, p. 411-423 13 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)

Human basophils activated by mast cell-derived IL-3 express retinaldehyde dehydrogenase-II and produce the immunoregulatory mediator retinoic acid

Spiegl, N., Didichenko, S., McCaffery, P., Langen, H. & Dahinden, C. A., 1 Nov 2008, In : Blood. 112, 9, p. 3762-3771 10 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)
2009

Restricted patterns of Hoxd10 and Hoxd11 set segmental differences in motoneuron subtype complement in the lumbosacral spinal cord

Misra, M., Shah, V., Carpenter, E., McCaffery, P. & Lance-Jones, C., 1 Jun 2009, In : Developmental Biology. 330, 1, p. 54-72 19 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2010

HPLC/MS(N) analysis of retinoids

Evans, J. E. & McCaffery, P., May 2010, In : Methods in Molecular Biology. 652, p. 149-162 14 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Photoperiodic regulation of retinoic acid signaling in the hypothalamus

Shearer, K. D., Goodman, T. H., Ross, A., Reilly, L., Morgan, P. J. & McCaffery, P. J. A., Jan 2010, In : Journal of Neurochemistry. 112, 1, p. 246-257 12 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)
2011

Retinoic acid and affective disorders: the evidence for an association

Bremner, J. D., Shearer, K. D. & McCaffery, P. J., 2011, In : Journal of Clinical Psychiatry. 73, 1, p. 37-50 14 p.

Research output: Contribution to journalArticle

84 Citations (Scopus)

Retinoic acid influences neuronal migration from the ganglionic eminence to the cerebral cortex

Crandall, J. E., Goodman, T., McCarthy, D. M., Duester, G., Bhide, P. G., Draeger, U. C. & McCaffery, P., Nov 2011, In : Journal of Neurochemistry. 119, 4, p. 723-735 13 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)
2012

A paradoxical teratogenic mechanism for retinoic acid

Lee, L. M. Y., Leung, C-Y., Tang, W. W. C., Choi, H-L., Leung, Y-C., McCaffery, P. J., Wang, C-C., Woolf, A. S. & Shum, A. S. W., 21 Aug 2012, In : PNAS. 109, 34, p. 13668-13673 6 p.

Research output: Contribution to journalArticle

75 Citations (Scopus)

Astrocytes as a regulated source of retinoic acid for the brain

Shearer, K. D., Fragoso, Y. D., Clagett-Dame, M. & McCaffery, P. J., Dec 2012, In : Glia. 60, 12, p. 1964-1976 13 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

High expression of retinoic acid receptors and synthetic enzymes in the human hippocampus

Fragoso, Y. D., Shearer, K. D., Sementilli, A., de Carvalho, L. V. & McCaffery, P. J., Apr 2012, In : Brain Structure and Function. 217, 2, p. 473-483 11 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Influence of isotretinoin on hippocampal-based learning in human subjects

Ormerod, A., Thind, C. K., Rice, S. A., Reid, I. C., Williams, J. H. G. & McCaffery, P. J. A., Jun 2012, In : Psychopharmacology. 221, 4, p. 667-674 8 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Patterning of retinoic acid signaling and cell proliferation in the hippocampus

Goodman, T., Crandall, J. E., Nanescu, S. E., Quadro, L., Shearer, K., Ross, A. & McCaffery, P., Nov 2012, In : Hippocampus. 22, 11, p. 2171-2183 13 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)

Photoperiodic Expression of Two RALDH Enzymes and the Regulation of Cell Proliferation by Retinoic Acid in the Rat Hypothalamus

Shearer, K. D., Stoney, P. N., Nanescu, S. E., Helfer, G., Barrett, P., Ross, A. W., Morgan, P. J. & McCaffery, P., Aug 2012, In : Journal of Neurochemistry. 122, 4, p. 789-799 11 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Photoperiod regulates vitamin A and Wnt/β-catenin signaling in F344 rats

Helfer, G., Ross, A. W., Russell, L., Thomson, L. M., Shearer, K. D., Goodman, T. H., McCaffery, P. J. & Morgan, P. J., 1 Feb 2012, In : Endocrinology. 153, 2, p. 815-824 10 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)
2013
Open Access
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30 Citations (Scopus)
4 Downloads (Pure)
2014

The Expression and Roles of Nde1 and Ndel1 in the Adult Mammalian Central Nervous System

Pei, Z., Lang, B., Fragoso, Y. D., Shearer, K. D., Zhao, L., McCaffery, P. J. A., Shen, S., Ding, Y. Q., McCaig, C. D. & Collinson, J. M., 20 Jun 2014, In : Neuroscience. 271, p. 119-136 18 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
4 Downloads (Pure)
2015

Expression in the human brain of retinoic acid induced 1, a protein associated with neurobehavioural disorders

Fragoso, Y. D., Stoney, P. N., Shearer, K. D., Sementilli, A., Nanescu, S. E., Sementilli, P. & McCaffery, P., Mar 2015, In : Brain Structure and Function. 220, 2, p. 1195-1203 9 p.

Research output: Contribution to journalArticle

Open Access
File
11 Citations (Scopus)
4 Downloads (Pure)

Fenretinide prevents obesity in aged female mice in association with increased retinoid and estrogen-signaling

Shearer, K. D., Morrice, N., Henderson, C., Reekie, J., McIlroy, G. D., McCaffery, P. J., Delibegovic, M. & Mody, N., Aug 2015, In : Obesity. 23, 8, p. 1655-1662 8 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2016
Open Access
File
12 Citations (Scopus)
11 Downloads (Pure)

A Vitamin on the Mind: New Discoveries on Control of the Brain by Vitamin A

Stoney, P. N. & McCaffery, P., 2016, In : World Review in Nutrition and Dietetics. 115, p. 98-108 11 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
5 Downloads (Pure)

Expression of the retinoic acid catabolic enzyme CYP26B1 in the human brain to maintain signaling homeostasis

Stoney, P. N., Fragoso, Y., Bu Saeed, R., Ashton, A., Goodman, T., Simons, C., Gomaa, M. S., Sementilli, A., Sementilli, L., Ross, A. W., Morgan, P. J. & McCaffery, P. J., Jul 2016, In : Brain Structure and Function. 221, 6, p. 3315-3326 12 p.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
6 Downloads (Pure)

Targeting Retinoid Receptors to Treat Schizophrenia: Rationale and Progress to Date

Lerner, V., McCaffery, P. J. A. & Ritsner, M. S., 1 Apr 2016, In : CNS Drugs. 30, 4, p. 269-280 12 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Thyroid hormone activation of retinoic acid synthesis in hypothalamic tanycytes

Stoney, P. N., Helfer, G., Rodrigues, D., Morgan, P. J. & McCaffery, P., Mar 2016, In : Glia. 64, 3, p. 425-439 15 p.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
7 Downloads (Pure)
2017

A seasonal switch in histone deacetylase gene expression in the hypothalamus and their capacity to modulate nuclear signaling pathways

Stoney, P. N., Rodrigues, D., Helfer, G., Khatib, T., Ashton, A., Hay, E. A., Starr, R., Kociszewska, D., Morgan, P. & McCaffery, P., Mar 2017, In : Brain, Behavior, and Immunity. 61, p. 340-352 13 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
11 Downloads (Pure)

Perturbation of Retinoid Homeostasis Increases Malformation Risk in Embryos Exposed to Pregestational Diabetes

Lee, L. M. Y., Leung, M. B. W., Kwok, R. C. Y., Leung, Y-C., Wang, C-C., McCaffery, P. J., Copp, A. J. & Shum, A. S. W., Apr 2017, In : Diabetes. 66, 4, p. 1041-1051 11 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
3 Downloads (Pure)
2018

Neurogenesis in Response to Synthetic Retinoids at Different Temporal Scales

Haffez, H., Khatib, T., McCaffery, P., Przyborski, S., Redfern, C. & Whiting, A., Mar 2018, In : Molecular Neurobiology. 55, 3, p. 1942-1950 9 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
7 Downloads (Pure)