Research output per year
Research output per year
Personal profile
Research Profile
Research Interests:
My research interests focus on metabolism of the microbial community that inhabits the human intestine and how it can be modulated by diet to improve human health. Key interests include:
- Microbial fermentation of dietary non-digestible carbohydrates (fibre)
- Short-chain fatty acid production by the gut microbiota
- Functional roles of specific gut microbes
- Microbial community interactions during dietary fibre fermentation
- Mathematical modelling of microbial metabolism
- Influence of fibre structure on microbial community fermentation
Activities
Clarivate (Web of Science) highly cited researcher 2018-2020
Scientific Advisory Board member Enterobiotix Ltd., Aberdeen, 2015-2020
Scientific Advisory Board member of Limagrain Ingredients via Consultancy firm Nutrikeo, Clermont-Ferrand, France, since 2020
International Centre for Aquaculture Research and Development (ICARD) member, since 2015
Visiting Fellow at the Center for Advanced Studies at Ludwig-Maximilians-Universitaet Muenchen, Nov 2018
International Life Sciences Institute (ILSI) Europe Workshop ‘The role of gut derived short chain fatty acids in human health’, 28-29.11.2018, invited expert
Supervision
PhD student Xiaolei Ze (2009-2013, co-supervisor) ‘Degradation and utilization of resistant starch by microbiota in the human large intestine’
PhD student Timo Kramer (2016-2021) ‘Molecular and physiological characteriwsation of Pectinatus frisingensis’
PhD student Michael Solvang (2017-2021) ‘Development of novel food ingredients that promote health via modulation of the gut microbiota’
PhD student Noshin Daud (2017-2021, co-supervisor) ‘Interactions Between Food-Borne Mycotoxins and Human Gut Microbiota'
PhD student Galiana Lo (2018-2021, co-supervisor) ‘Mining and modelling the human gut microbiome to elucidate its metabolic potential’
PhD student Simbarashe Biti (2019-2022, co-supervisor) ‘Sustainable adsorbents from waste for feasible post-combustion CO2 capture’
PhD student Daniel Underwood (2019-2023, co-supervisor) ‘Interactions during S. aureus internalisation in macrophages and non-professional phagocytic cells’
Teaching
Lectures at 2nd, 4th and 5th year level for seven courses at UoA, spanning microbiology, genetics, nutrition, diabetes and disease prevention
Practical in 2nd year Genetics
Supervision of Honours and MSc student research projects
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Life Sciences & Medicine, Doctoral Degree, : Molecular biological studies on Marinococcus halophilus – Identification of genes for ectoine biosynthesis and their osmoregulated expression in Escherichia coli , University of Bonn
Award Date: 13 Dec 1996
Biological Sciences, Diploma, The stabilising effect of compatible solutes on drying and storage of Escherichia coli, University of Bonn
Award Date: 5 Oct 1992
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Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Beyond purified dietary fibre supplements: compositional variation between cell wall fibre from different plants influences human faecal microbiota activity and growth in vitro
Solvang, M., Farquharson, F., Sanhueza, D., Horgan, G., Russell, W. & Louis, P., 28 Mar 2023, (E-pub ahead of print) In: Environmental Microbiology. 21 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Habitual consumption of high-fibre bread fortified with bean hulls increased plasma indole-3-propionic concentration and decreased putrescine and deoxycholic acid faecal concentrations in healthy volunteers
Sayegh, M., Ni, Q. Q., Ranawana, V., Raikos, V., Hayward, N. J., Hayes, H., Duncan, G., Cantlay, L., Farquharson, F., Solvang, M., Horgan, G., Louis, P., Russell, W., Clegg, M., Thies, F. & Neacsu, M., 27 Feb 2023, (E-pub ahead of print) In: British Journal of Nutrition. p. 1-36 36 p.Research output: Contribution to journal › Article › peer-review
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Process-based modelling of Microbial community dynamics in the human colon
Kettle, H., Louis, P. & Flint, H. J., 12 Oct 2022, In: Journal of the Royal Society Interface. 19, 195, 14 p., 20220489.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Downloads (Pure) -
Microbial lactate utilisation and the stability of the gut microbiome
Louis, P., Duncan, S., Sheridan, P., Walker, A. & Flint, H. J., 4 May 2022, (E-pub ahead of print) In: Gut Microbiome.Research output: Contribution to journal › Article › peer-review
Open Access -
Long-term personalized low FODMAP diet improves symptoms and maintains luminal Bifidobacteria abundance in irritable bowel syndrome
Staudacher, H. M., Rossi, M., Kaminski, T., Dimidi, E., Ralph, F. SE., Wilson, B., Dallimer, M., Wilson, B., Martin, L. D., Louis, P., Lomer, M. C., Irving, P. M. & Whelan, K., 1 Apr 2022, In: Neurogastroenterology and Motility. 34, 4, 11 p., e14241.Research output: Contribution to journal › Article › peer-review
Open AccessFile22 Citations (Scopus)1 Downloads (Pure)
Datasets
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Data from: Impact of diet and individual variation on intestinal microbiota composition and fermentation products in obese men
Salonen, A. (Creator), Lahti, L. (Creator), Salojärvi, J. (Creator), Holtrop, G. (Creator), Korpela, K. (Creator), Duncan, S. (Creator), Date, P. (Creator), Farquharson, F. (Creator), Johnstone, A. (Creator), Lobley, G. (Creator), Louis, P. (Creator), Flint, H. (Creator) & de Vos, W. M. (Creator), Dryad Digital Repository, 9 Apr 2015
DOI: 10.5061/dryad.7b37k
Dataset
Prizes
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Highly Cited Researchers™ 2022
Duncan, Sylvia (Recipient), Flint, Harry (Recipient), Francis, Jill (Recipient), Johnston, Marie (Recipient), Louis, Petra (Recipient), Prosser, James (Recipient), Scott, Karen (Recipient), Smith, Pete (Recipient) & Walker, Alan (Recipient), 2022
Prize: Other distinction
Impacts
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Commercial applications of pioneering research on the human gut microbiota
Karen Scott (Participant), Petra Louis (Participant), Alan Walker (Participant), Sylvia Duncan (Participant) & Harry Flint (Participant)
Impact: Economic Impacts, Quality of life Impacts