Research output per year
Research output per year
Personal profile
Research Profile
Research Interests:
My research interests focus on metabolism of the microbial community that inhabits the human intestine and how it can be modulated by diet to improve human health. Key interests include:
- Microbial fermentation of dietary non-digestible carbohydrates (fibre)
- Short-chain fatty acid production by the gut microbiota
- Functional roles of specific gut microbes
- Microbial community interactions during dietary fibre fermentation
- Mathematical modelling of microbial metabolism
- Influence of fibre structure on microbial community fermentation
Activities
Clarivate (Web of Science) highly cited researcher 2018-2020
Scientific Advisory Board member Enterobiotix Ltd., Aberdeen, 2015-2020
Scientific Advisory Board member of Limagrain Ingredients via Consultancy firm Nutrikeo, Clermont-Ferrand, France, since 2020
International Centre for Aquaculture Research and Development (ICARD) member, since 2015
Visiting Fellow at the Center for Advanced Studies at Ludwig-Maximilians-Universitaet Muenchen, Nov 2018
International Life Sciences Institute (ILSI) Europe Workshop ‘The role of gut derived short chain fatty acids in human health’, 28-29.11.2018, invited expert
Supervision
PhD student Xiaolei Ze (2009-2013, co-supervisor) ‘Degradation and utilization of resistant starch by microbiota in the human large intestine’
PhD student Timo Kramer (2016-2021) ‘Molecular and physiological characteriwsation of Pectinatus frisingensis’
PhD student Michael Solvang (2017-2021) ‘Development of novel food ingredients that promote health via modulation of the gut microbiota’
PhD student Noshin Daud (2017-2021, co-supervisor) ‘Interactions Between Food-Borne Mycotoxins and Human Gut Microbiota'
PhD student Galiana Lo (2018-2021, co-supervisor) ‘Mining and modelling the human gut microbiome to elucidate its metabolic potential’
PhD student Simbarashe Biti (2019-2022, co-supervisor) ‘Sustainable adsorbents from waste for feasible post-combustion CO2 capture’
PhD student Daniel Underwood (2019-2023, co-supervisor) ‘Interactions during S. aureus internalisation in macrophages and non-professional phagocytic cells’
Teaching
Lectures at 2nd, 4th and 5th year level for seven courses at UoA, spanning microbiology, genetics, nutrition, diabetes and disease prevention
Practical in 2nd year Genetics
Supervision of Honours and MSc student research projects
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Life Sciences & Medicine, Doctoral Degree, University of Bonn
Award Date: 13 Dec 1996
Biological Sciences, Diploma, University of Bonn
Award Date: 5 Oct 1992
Fingerprint
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Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Microbial lactate utilisation and the stability of the gut microbiome
Louis, P., Duncan, S., Sheridan, P., Walker, A. & Flint, H. J., 4 May 2022, (E-pub ahead of print) In: Gut Microbiome.Research output: Contribution to journal › Article › peer-review
Open Access -
Higher total faecal short chain fatty concentrations correlate with increasing proportions of butyrate and decreasing proportions of branched chain fatty acids across multiple human studies
Scott, K., LaBouyer, M., Holtrop, G., Horgan, G., Gratz, S., Belenguer, A., Smith, N., Walker, A., Duncan, S., Johnstone, A. & Louis, P., 30 Mar 2022, In: Gut Microbiome. 3, 14 p., e2.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Distribution, organization and expression of genes concerned with anaerobic lactate utilization in human intestinal bacteria
Sheridan, P., Louis, P., Tsompanidou, E., Shaw, S., Harmsen, H. J. M., Duncan, S., Flint, H. J. & Walker, A., 25 Jan 2022, (E-pub ahead of print) In: Microbial Genomics.Research output: Contribution to journal › Article › peer-review
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Immune Responsiveness to LPS Determines Risk of Childhood Wheeze and Asthma in 17q21 Risk Allele Carriers
Illi, S., Depner, M., Pfefferle, P. I., Renz, H., Roduit, C., Taft, D. H., Kalanetra, K. M., Mills, D. A., Farquharson, F. M., Louis, P., Schmausser-Hechfellner, E., Divaret-Chauveau, A., Lauener, R., Karvonen, A. M., Pekkanen, J., Kirjavainen, P. V., Roponen, M., Riedler, J., Kabesch, M., Schaub, B. & 2 others, , 17 Dec 2021, In: American journal of respiratory and critical care medicine. 205, 6, p. 641-650 10 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Dietary fibre complexity and its influence on functional groups of the human gut microbiota
Louis, P., Solvang, M., Duncan, S., Walker, A. & Mukhopadhya, I., 30 Nov 2021, In: Proceedings of the Nutrition Society. 80, 4, p. 386–397 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile14 Downloads (Pure)
Datasets
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Data from: Impact of diet and individual variation on intestinal microbiota composition and fermentation products in obese men
Salonen, A. (Creator), Lahti, L. (Creator), Salojärvi, J. (Creator), Holtrop, G. (Creator), Korpela, K. (Creator), Duncan, S. (Creator), Date, P. (Creator), Farquharson, F. (Creator), Johnstone, A. (Creator), Lobley, G. (Creator), Louis, P. (Creator), Flint, H. (Creator) & de Vos, W. M. (Creator), Dryad Digital Repository, 9 Apr 2015
DOI: 10.5061/dryad.7b37k
Dataset
Impacts
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Commercial applications of pioneering research on the human gut microbiota
Karen Scott (Participant), Petra Louis (Participant), Alan Walker (Participant), Sylvia Duncan (Participant) & Harry Flint (Participant)
Impact: Economic Impacts, Quality of life Impacts