A 12 country field study of the EORTC QLQ-C30 (version 3.0) and the head and neck cancer specific module (EORTC QLQ-H&N35) in head and neck patients.

K Bjordal, A de Graeff, Peter Fayers, E Hammerlid, C van Pottelsberghe, D Curran, M Ahlner-Elmqvist, E J Maher, J W Meyza, A Brédart, A L Söderholm, J J Arraras, J S Feine, H Abendstein, R P Morton, T Pignon, P Huguenin, A Bottomly, S Kaasa, EORTC Quality of Life Group

Research output: Contribution to journalArticle

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Abstract

This study tests the reliability and validity of the European Organization for Research and Treatment of Cancer (EORTC) head and neck cancer module (QLQ-H&N35) and version 3.0 of the EORTC Core Questionnaire (QLQ-C30) in 622 head and neck cancer patients from 12 countries. The patients completed the QLQ-C30, the QLQ-H&N35 and a debriefing questionnaire before antineoplastic treatment or at a follow-up. 232 patients receiving treatment completed a second questionnaire after treatment. Compliance was high and the questionnaire was well accepted by the patients. Multitrait scaling analysis confirmed the proposed scale structure of the QLQ-H&N35. The QLQ-H&N35 was responsive to differences between disease status, site and patients with different Karnofsky performance status, and to changes over time. The new physical functioning scale (with a four-point response format) of version 3.0 of the QLQ-C30 was shown to be more reliable than previous versions. Thus, the QLQ-H&N35, in conjunction with the QLQ-C30, appears to be reliable, valid and applicable to broad multicultural samples of head and neck cancer patients.
Original languageEnglish
Pages (from-to)1796-1807
Number of pages12
JournalEuropean Journal of Cancer
Volume36
Issue number14
DOIs
Publication statusPublished - Sep 2000

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Head and Neck Neoplasms
Neck
Head
Research
Neoplasms
Therapeutics
Karnofsky Performance Status
Reproducibility of Results
Antineoplastic Agents
Compliance
Surveys and Questionnaires

Keywords

  • Adult
  • Aged
  • Aged, 80 and over
  • Carcinoma, Squamous Cell
  • Female
  • Head and Neck Neoplasms
  • Health Status Indicators
  • Humans
  • Male
  • Middle Aged
  • Quality of Life
  • Questionnaires
  • Sensitivity and Specificity
  • Time Factors
  • quality of life
  • head and neck cancer
  • assessment
  • questionnaire
  • validation
  • EORTC QLQ-C30
  • EORTC QLQ-H&N35

Cite this

A 12 country field study of the EORTC QLQ-C30 (version 3.0) and the head and neck cancer specific module (EORTC QLQ-H&N35) in head and neck patients. / Bjordal, K; de Graeff, A; Fayers, Peter; Hammerlid, E; van Pottelsberghe, C; Curran, D; Ahlner-Elmqvist, M; Maher, E J; Meyza, J W; Brédart, A; Söderholm, A L; Arraras, J J; Feine, J S; Abendstein, H; Morton, R P; Pignon, T; Huguenin, P; Bottomly, A; Kaasa, S; EORTC Quality of Life Group.

In: European Journal of Cancer, Vol. 36, No. 14, 09.2000, p. 1796-1807.

Research output: Contribution to journalArticle

Bjordal, K, de Graeff, A, Fayers, P, Hammerlid, E, van Pottelsberghe, C, Curran, D, Ahlner-Elmqvist, M, Maher, EJ, Meyza, JW, Brédart, A, Söderholm, AL, Arraras, JJ, Feine, JS, Abendstein, H, Morton, RP, Pignon, T, Huguenin, P, Bottomly, A, Kaasa, S & EORTC Quality of Life Group 2000, 'A 12 country field study of the EORTC QLQ-C30 (version 3.0) and the head and neck cancer specific module (EORTC QLQ-H&N35) in head and neck patients.', European Journal of Cancer, vol. 36, no. 14, pp. 1796-1807. https://doi.org/10.1016/S0959-8049(00)00186-6
Bjordal, K ; de Graeff, A ; Fayers, Peter ; Hammerlid, E ; van Pottelsberghe, C ; Curran, D ; Ahlner-Elmqvist, M ; Maher, E J ; Meyza, J W ; Brédart, A ; Söderholm, A L ; Arraras, J J ; Feine, J S ; Abendstein, H ; Morton, R P ; Pignon, T ; Huguenin, P ; Bottomly, A ; Kaasa, S ; EORTC Quality of Life Group. / A 12 country field study of the EORTC QLQ-C30 (version 3.0) and the head and neck cancer specific module (EORTC QLQ-H&N35) in head and neck patients. In: European Journal of Cancer. 2000 ; Vol. 36, No. 14. pp. 1796-1807.
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AU - de Graeff, A

AU - Fayers, Peter

AU - Hammerlid, E

AU - van Pottelsberghe, C

AU - Curran, D

AU - Ahlner-Elmqvist, M

AU - Maher, E J

AU - Meyza, J W

AU - Brédart, A

AU - Söderholm, A L

AU - Arraras, J J

AU - Feine, J S

AU - Abendstein, H

AU - Morton, R P

AU - Pignon, T

AU - Huguenin, P

AU - Bottomly, A

AU - Kaasa, S

AU - EORTC Quality of Life Group

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N2 - This study tests the reliability and validity of the European Organization for Research and Treatment of Cancer (EORTC) head and neck cancer module (QLQ-H&N35) and version 3.0 of the EORTC Core Questionnaire (QLQ-C30) in 622 head and neck cancer patients from 12 countries. The patients completed the QLQ-C30, the QLQ-H&N35 and a debriefing questionnaire before antineoplastic treatment or at a follow-up. 232 patients receiving treatment completed a second questionnaire after treatment. Compliance was high and the questionnaire was well accepted by the patients. Multitrait scaling analysis confirmed the proposed scale structure of the QLQ-H&N35. The QLQ-H&N35 was responsive to differences between disease status, site and patients with different Karnofsky performance status, and to changes over time. The new physical functioning scale (with a four-point response format) of version 3.0 of the QLQ-C30 was shown to be more reliable than previous versions. Thus, the QLQ-H&N35, in conjunction with the QLQ-C30, appears to be reliable, valid and applicable to broad multicultural samples of head and neck cancer patients.

AB - This study tests the reliability and validity of the European Organization for Research and Treatment of Cancer (EORTC) head and neck cancer module (QLQ-H&N35) and version 3.0 of the EORTC Core Questionnaire (QLQ-C30) in 622 head and neck cancer patients from 12 countries. The patients completed the QLQ-C30, the QLQ-H&N35 and a debriefing questionnaire before antineoplastic treatment or at a follow-up. 232 patients receiving treatment completed a second questionnaire after treatment. Compliance was high and the questionnaire was well accepted by the patients. Multitrait scaling analysis confirmed the proposed scale structure of the QLQ-H&N35. The QLQ-H&N35 was responsive to differences between disease status, site and patients with different Karnofsky performance status, and to changes over time. The new physical functioning scale (with a four-point response format) of version 3.0 of the QLQ-C30 was shown to be more reliable than previous versions. Thus, the QLQ-H&N35, in conjunction with the QLQ-C30, appears to be reliable, valid and applicable to broad multicultural samples of head and neck cancer patients.

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KW - Aged, 80 and over

KW - Carcinoma, Squamous Cell

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KW - Health Status Indicators

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KW - Male

KW - Middle Aged

KW - Quality of Life

KW - Questionnaires

KW - Sensitivity and Specificity

KW - Time Factors

KW - quality of life

KW - head and neck cancer

KW - assessment

KW - questionnaire

KW - validation

KW - EORTC QLQ-C30

KW - EORTC QLQ-H&N35

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DO - 10.1016/S0959-8049(00)00186-6

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VL - 36

SP - 1796

EP - 1807

JO - European Journal of Cancer

JF - European Journal of Cancer

SN - 0959-8049

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