A miniaturised method for immunoglobulin allotype serology

Neil Thomas Young, J Street, C Darke

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

A modification of the classic haemagglutination inhibition method for immunoglobulin allotyping is described which employs reagent volumes of 2 microliters compared with the 25 microliter volumes commonly used in other serological allotyping methods. No loss of sensitivity or specificity was associated with the miniaturised method when compared to the standard tile technique. This method simplifies the large scale phenotyping and screening of sera and permits considerable savings of valuable reagents to be made.
Original languageEnglish
Pages (from-to)143-147
Number of pages5
JournalJournal of Immunological Methods
Volume122
Issue number1
DOIs
Publication statusPublished - 15 Aug 1989

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Keywords

  • Gene Frequency
  • Hemagglutination Inhibition Tests
  • Humans
  • Immunoglobulin Allotypes
  • Microchemistry
  • Wales
  • Miniaturized Method
  • Gm Allotype Frequency

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