A Mycobacterium tuberculosis IS6110 preferential locus (ipl) for insertion into the genome

Z G  Fang; Ken J. Forbes

A Mycobacterium tuberculosis IS6110 preferential locus (ipl) for insertion into the genome

Z G Fang, Ken J. Forbes

Applied Medicine

Research output: Contribution to journal › Article › peer-review

68 Citations (Scopus)

Abstract

A 267-nucleotide Mycobacterium tuberculosis genomic sequence (ipl, the IS6110 preferential locus) which can harbor the insertion sequence IS6110 at six alternative locations has been identified in some three-quarters of the isolates tested. Only one IS6110 copy was observed at this locus in the ipl::IS6110(+)-containing isolates tested, and all insertions had the same orientation. The implications of this finding for IS6110 fingerprint typing methods is discussed in this work.

Original language	English
Pages (from-to)	479-481
Number of pages	3
Journal	Journal of Clinical Microbiology
Volume	35
Issue number	2
Publication status	Published - Feb 1997

Keywords

complex strains
element
epidemiology
tool

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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abstract = "A 267-nucleotide Mycobacterium tuberculosis genomic sequence (ipl, the IS6110 preferential locus) which can harbor the insertion sequence IS6110 at six alternative locations has been identified in some three-quarters of the isolates tested. Only one IS6110 copy was observed at this locus in the ipl::IS6110(+)-containing isolates tested, and all insertions had the same orientation. The implications of this finding for IS6110 fingerprint typing methods is discussed in this work.",

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KW - element

KW - epidemiology

KW - tool

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A Mycobacterium tuberculosis IS6110 preferential locus (ipl) for insertion into the genome

Abstract

Keywords

UN SDGs

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