Addressing the evidence to practice gap for complex interventions in primary care: a systematic review of reviews protocol

Rosa Lau, Fiona Stevenson, Bie Nio Ong, Krysia Dziedzic, Sandra Eldridge, Hazel Everitt, Anne Kennedy, Evangelos Kontopantelis, Paul Little, Nadeem Qureshi, Anne Rogers, Shaun Treweek, Richard Peacock, Elizabeth Murray

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Abstract

INTRODUCTION: Getting the results of research implemented into routine healthcare is often a challenge. The disconnect between the development and implementation of evidence into practice is called the 'second translational gap' and is particularly apparent in primary care. To address this gap, we plan to identify, summarise and synthesise currently available evidence by undertaking a systematic review of reviews to: (1) explore barriers and facilitators of implementation of research evidence or complex interventions, and (2) assess the effectiveness of strategies in facilitating implementation of complex interventions in primary care.

METHODS AND ANALYSIS: This is a protocol for a systematic review of reviews. We will search MEDLINE, EMBASE, the Cochrane Library, CINAHL and PsycINFO up until December 2013. We will check reference lists of included studies for further studies. Two authors will independently screen the titles and abstracts identified from the search; any discrepancies will be resolved by discussion and consensus. Full-text papers will be obtained and relevant reviews will be selected against inclusion criteria. Eligible reviews have to be based on predominantly primary care in developed countries and examine either factors to implementation or, the effectiveness of strategies to optimise implementation. Data from eligible reviews will be extracted using standardised data abstraction forms. For barriers and facilitators, data will be synthesised using an interpretative meta-synthesis approach. For implementation strategies, findings will be summarised and described narratively and synthesised using a framework approach. All findings will be reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.

ETHICS AND DISSEMINATION: Ethical approval is not required. The review findings will inform the work of the design and implementation of future studies and will be of interest to a wide audience including health professionals, researchers, health service or commissioning managers and policymakers.

TRIAL REGISTRATION NUMBER: Protocol registration number (PROSPERO CRD42014009410).

Original languageEnglish
Article numbere005548
JournalBMJ Open
Volume4
Issue number6
DOIs
Publication statusPublished - 2014

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Primary Health Care
Research
Developed Countries
MEDLINE
Libraries
Health Services
Meta-Analysis
Research Personnel
Guidelines
Delivery of Health Care
Health
Professional Practice Gaps

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Lau, R., Stevenson, F., Ong, B. N., Dziedzic, K., Eldridge, S., Everitt, H., ... Murray, E. (2014). Addressing the evidence to practice gap for complex interventions in primary care: a systematic review of reviews protocol. BMJ Open, 4(6), [e005548]. https://doi.org/10.1136/bmjopen-2014-005548

Addressing the evidence to practice gap for complex interventions in primary care : a systematic review of reviews protocol. / Lau, Rosa; Stevenson, Fiona; Ong, Bie Nio; Dziedzic, Krysia; Eldridge, Sandra; Everitt, Hazel; Kennedy, Anne; Kontopantelis, Evangelos; Little, Paul; Qureshi, Nadeem; Rogers, Anne; Treweek, Shaun; Peacock, Richard; Murray, Elizabeth.

In: BMJ Open, Vol. 4, No. 6, e005548, 2014.

Research output: Contribution to journalArticle

Lau, R, Stevenson, F, Ong, BN, Dziedzic, K, Eldridge, S, Everitt, H, Kennedy, A, Kontopantelis, E, Little, P, Qureshi, N, Rogers, A, Treweek, S, Peacock, R & Murray, E 2014, 'Addressing the evidence to practice gap for complex interventions in primary care: a systematic review of reviews protocol', BMJ Open, vol. 4, no. 6, e005548. https://doi.org/10.1136/bmjopen-2014-005548
Lau, Rosa ; Stevenson, Fiona ; Ong, Bie Nio ; Dziedzic, Krysia ; Eldridge, Sandra ; Everitt, Hazel ; Kennedy, Anne ; Kontopantelis, Evangelos ; Little, Paul ; Qureshi, Nadeem ; Rogers, Anne ; Treweek, Shaun ; Peacock, Richard ; Murray, Elizabeth. / Addressing the evidence to practice gap for complex interventions in primary care : a systematic review of reviews protocol. In: BMJ Open. 2014 ; Vol. 4, No. 6.
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AU - Lau, Rosa

AU - Stevenson, Fiona

AU - Ong, Bie Nio

AU - Dziedzic, Krysia

AU - Eldridge, Sandra

AU - Everitt, Hazel

AU - Kennedy, Anne

AU - Kontopantelis, Evangelos

AU - Little, Paul

AU - Qureshi, Nadeem

AU - Rogers, Anne

AU - Treweek, Shaun

AU - Peacock, Richard

AU - Murray, Elizabeth

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N2 - INTRODUCTION: Getting the results of research implemented into routine healthcare is often a challenge. The disconnect between the development and implementation of evidence into practice is called the 'second translational gap' and is particularly apparent in primary care. To address this gap, we plan to identify, summarise and synthesise currently available evidence by undertaking a systematic review of reviews to: (1) explore barriers and facilitators of implementation of research evidence or complex interventions, and (2) assess the effectiveness of strategies in facilitating implementation of complex interventions in primary care.METHODS AND ANALYSIS: This is a protocol for a systematic review of reviews. We will search MEDLINE, EMBASE, the Cochrane Library, CINAHL and PsycINFO up until December 2013. We will check reference lists of included studies for further studies. Two authors will independently screen the titles and abstracts identified from the search; any discrepancies will be resolved by discussion and consensus. Full-text papers will be obtained and relevant reviews will be selected against inclusion criteria. Eligible reviews have to be based on predominantly primary care in developed countries and examine either factors to implementation or, the effectiveness of strategies to optimise implementation. Data from eligible reviews will be extracted using standardised data abstraction forms. For barriers and facilitators, data will be synthesised using an interpretative meta-synthesis approach. For implementation strategies, findings will be summarised and described narratively and synthesised using a framework approach. All findings will be reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.ETHICS AND DISSEMINATION: Ethical approval is not required. The review findings will inform the work of the design and implementation of future studies and will be of interest to a wide audience including health professionals, researchers, health service or commissioning managers and policymakers.TRIAL REGISTRATION NUMBER: Protocol registration number (PROSPERO CRD42014009410).

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