BacA-mediated bleomycin sensitivity in Sinorhizobium meliloti is independent of the unusual lipid A modification

Gail Patricia Ferguson, A. Jansen, V. L. Marlow, G. C. Walker

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Sinorhizobium meliloti bacA mutants are symbiotically defective, deoxycholate sensitive, and bleomycin resistant. We show that the bleomycin resistance phenotype is independent of the lipid A alteration and that the changes giving rise to both phenotypes are likely to be involved in the inability of bacA mutants to persist within their hosts.

Original languageEnglish
Pages (from-to)3143-3148
Number of pages5
JournalJournal of Bacteriology
Volume188
Issue number8
DOIs
Publication statusPublished - Apr 2006

Keywords

  • RHIZOBIUM-MELILOTI
  • BACTEROID DEVELOPMENT
  • GENETIC-ANALYSIS
  • FATTY-ACIDS
  • PROTEIN
  • SBMA
  • LEGUMINOSARUM
  • SYMBIOSIS
  • MUTANTS
  • NODULES

Cite this

BacA-mediated bleomycin sensitivity in Sinorhizobium meliloti is independent of the unusual lipid A modification. / Ferguson, Gail Patricia; Jansen, A.; Marlow, V. L.; Walker, G. C.

In: Journal of Bacteriology, Vol. 188, No. 8, 04.2006, p. 3143-3148.

Research output: Contribution to journalArticle

Ferguson, Gail Patricia ; Jansen, A. ; Marlow, V. L. ; Walker, G. C. / BacA-mediated bleomycin sensitivity in Sinorhizobium meliloti is independent of the unusual lipid A modification. In: Journal of Bacteriology. 2006 ; Vol. 188, No. 8. pp. 3143-3148.
@article{4f0d4874f2e84950b2c0be1aea00ada5,
title = "BacA-mediated bleomycin sensitivity in Sinorhizobium meliloti is independent of the unusual lipid A modification",
abstract = "Sinorhizobium meliloti bacA mutants are symbiotically defective, deoxycholate sensitive, and bleomycin resistant. We show that the bleomycin resistance phenotype is independent of the lipid A alteration and that the changes giving rise to both phenotypes are likely to be involved in the inability of bacA mutants to persist within their hosts.",
keywords = "RHIZOBIUM-MELILOTI, BACTEROID DEVELOPMENT, GENETIC-ANALYSIS, FATTY-ACIDS, PROTEIN, SBMA, LEGUMINOSARUM, SYMBIOSIS, MUTANTS, NODULES",
author = "Ferguson, {Gail Patricia} and A. Jansen and Marlow, {V. L.} and Walker, {G. C.}",
year = "2006",
month = "4",
doi = "10.1128/JB.188.8.3143-3148.2006",
language = "English",
volume = "188",
pages = "3143--3148",
journal = "Journal of Bacteriology",
issn = "0021-9193",
publisher = "American Society for Microbiology",
number = "8",

}

TY - JOUR

T1 - BacA-mediated bleomycin sensitivity in Sinorhizobium meliloti is independent of the unusual lipid A modification

AU - Ferguson, Gail Patricia

AU - Jansen, A.

AU - Marlow, V. L.

AU - Walker, G. C.

PY - 2006/4

Y1 - 2006/4

N2 - Sinorhizobium meliloti bacA mutants are symbiotically defective, deoxycholate sensitive, and bleomycin resistant. We show that the bleomycin resistance phenotype is independent of the lipid A alteration and that the changes giving rise to both phenotypes are likely to be involved in the inability of bacA mutants to persist within their hosts.

AB - Sinorhizobium meliloti bacA mutants are symbiotically defective, deoxycholate sensitive, and bleomycin resistant. We show that the bleomycin resistance phenotype is independent of the lipid A alteration and that the changes giving rise to both phenotypes are likely to be involved in the inability of bacA mutants to persist within their hosts.

KW - RHIZOBIUM-MELILOTI

KW - BACTEROID DEVELOPMENT

KW - GENETIC-ANALYSIS

KW - FATTY-ACIDS

KW - PROTEIN

KW - SBMA

KW - LEGUMINOSARUM

KW - SYMBIOSIS

KW - MUTANTS

KW - NODULES

U2 - 10.1128/JB.188.8.3143-3148.2006

DO - 10.1128/JB.188.8.3143-3148.2006

M3 - Article

VL - 188

SP - 3143

EP - 3148

JO - Journal of Bacteriology

JF - Journal of Bacteriology

SN - 0021-9193

IS - 8

ER -