BacA-mediated bleomycin sensitivity in Sinorhizobium meliloti is independent of the unusual lipid A modification

Gail Patricia Ferguson, A. Jansen, V. L. Marlow, G. C. Walker

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)

Abstract

Sinorhizobium meliloti bacA mutants are symbiotically defective, deoxycholate sensitive, and bleomycin resistant. We show that the bleomycin resistance phenotype is independent of the lipid A alteration and that the changes giving rise to both phenotypes are likely to be involved in the inability of bacA mutants to persist within their hosts.

Original languageEnglish
Pages (from-to)3143-3148
Number of pages5
JournalJournal of Bacteriology
Volume188
Issue number8
DOIs
Publication statusPublished - Apr 2006

Keywords

  • RHIZOBIUM-MELILOTI
  • BACTEROID DEVELOPMENT
  • GENETIC-ANALYSIS
  • FATTY-ACIDS
  • PROTEIN
  • SBMA
  • LEGUMINOSARUM
  • SYMBIOSIS
  • MUTANTS
  • NODULES

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