BacA-mediated bleomycin sensitivity in Sinorhizobium meliloti is independent of the unusual lipid A modification

Gail Patricia Ferguson; A. Jansen; V. L. Marlow; G. C. Walker

doi:10.1128/JB.188.8.3143-3148.2006

BacA-mediated bleomycin sensitivity in Sinorhizobium meliloti is independent of the unusual lipid A modification

Gail Patricia Ferguson, A. Jansen, V. L. Marlow, G. C. Walker

Applied Medicine

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Abstract

Sinorhizobium meliloti bacA mutants are symbiotically defective, deoxycholate sensitive, and bleomycin resistant. We show that the bleomycin resistance phenotype is independent of the lipid A alteration and that the changes giving rise to both phenotypes are likely to be involved in the inability of bacA mutants to persist within their hosts.

Original language	English
Pages (from-to)	3143-3148
Number of pages	5
Journal	Journal of Bacteriology
Volume	188
Issue number	8
DOIs	https://doi.org/10.1128/JB.188.8.3143-3148.2006
Publication status	Published - Apr 2006

Keywords

RHIZOBIUM-MELILOTI
BACTEROID DEVELOPMENT
GENETIC-ANALYSIS
FATTY-ACIDS
PROTEIN
SBMA
LEGUMINOSARUM
SYMBIOSIS
MUTANTS
NODULES

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10.1128/JB.188.8.3143-3148.2006

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title = "BacA-mediated bleomycin sensitivity in Sinorhizobium meliloti is independent of the unusual lipid A modification",

abstract = "Sinorhizobium meliloti bacA mutants are symbiotically defective, deoxycholate sensitive, and bleomycin resistant. We show that the bleomycin resistance phenotype is independent of the lipid A alteration and that the changes giving rise to both phenotypes are likely to be involved in the inability of bacA mutants to persist within their hosts.",

keywords = "RHIZOBIUM-MELILOTI, BACTEROID DEVELOPMENT, GENETIC-ANALYSIS, FATTY-ACIDS, PROTEIN, SBMA, LEGUMINOSARUM, SYMBIOSIS, MUTANTS, NODULES",

author = "Ferguson, {Gail Patricia} and A. Jansen and Marlow, {V. L.} and Walker, {G. C.}",

year = "2006",

month = apr,

doi = "10.1128/JB.188.8.3143-3148.2006",

language = "English",

volume = "188",

pages = "3143--3148",

journal = "Journal of Bacteriology",

issn = "0021-9193",

publisher = "American Society for Microbiology",

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}

TY - JOUR

T1 - BacA-mediated bleomycin sensitivity in Sinorhizobium meliloti is independent of the unusual lipid A modification

AU - Ferguson, Gail Patricia

AU - Jansen, A.

AU - Marlow, V. L.

AU - Walker, G. C.

PY - 2006/4

Y1 - 2006/4

N2 - Sinorhizobium meliloti bacA mutants are symbiotically defective, deoxycholate sensitive, and bleomycin resistant. We show that the bleomycin resistance phenotype is independent of the lipid A alteration and that the changes giving rise to both phenotypes are likely to be involved in the inability of bacA mutants to persist within their hosts.

AB - Sinorhizobium meliloti bacA mutants are symbiotically defective, deoxycholate sensitive, and bleomycin resistant. We show that the bleomycin resistance phenotype is independent of the lipid A alteration and that the changes giving rise to both phenotypes are likely to be involved in the inability of bacA mutants to persist within their hosts.

KW - RHIZOBIUM-MELILOTI

KW - BACTEROID DEVELOPMENT

KW - GENETIC-ANALYSIS

KW - FATTY-ACIDS

KW - PROTEIN

KW - SBMA

KW - LEGUMINOSARUM

KW - SYMBIOSIS

KW - MUTANTS

KW - NODULES

U2 - 10.1128/JB.188.8.3143-3148.2006

DO - 10.1128/JB.188.8.3143-3148.2006

M3 - Article

SN - 0021-9193

VL - 188

SP - 3143

EP - 3148

JO - Journal of Bacteriology

JF - Journal of Bacteriology

IS - 8

ER -

BacA-mediated bleomycin sensitivity in Sinorhizobium meliloti is independent of the unusual lipid A modification

Abstract

Keywords

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