BacA-mediated bleomycin sensitivity in Sinorhizobium meliloti is independent of the unusual lipid A modification

Gail Patricia Ferguson, A. Jansen, V. L. Marlow, G. C. Walker

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Sinorhizobium meliloti bacA mutants are symbiotically defective, deoxycholate sensitive, and bleomycin resistant. We show that the bleomycin resistance phenotype is independent of the lipid A alteration and that the changes giving rise to both phenotypes are likely to be involved in the inability of bacA mutants to persist within their hosts.

Original languageEnglish
Pages (from-to)3143-3148
Number of pages5
JournalJournal of Bacteriology
Volume188
Issue number8
DOIs
Publication statusPublished - Apr 2006

Keywords

  • RHIZOBIUM-MELILOTI
  • BACTEROID DEVELOPMENT
  • GENETIC-ANALYSIS
  • FATTY-ACIDS
  • PROTEIN
  • SBMA
  • LEGUMINOSARUM
  • SYMBIOSIS
  • MUTANTS
  • NODULES

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