Behavioural optimisation to address trial conduct challenges: case study in the UK-REBOA trial

Louisa Lawrie; Eilidh M. Duncan; Jan O. Jansen; Marion K. Campbell; Dan Brunsdon; Zoë Skea; Taylor Coffey; Claire Cochran; Katie Gillies

doi:10.1186/s13063-022-06341-6

Behavioural optimisation to address trial conduct challenges: case study in the UK-REBOA trial

Louisa Lawrie^* (Corresponding Author), Eilidh M. Duncan, Jan O. Jansen, Marion K. Campbell, Dan Brunsdon, Zoë Skea, Taylor Coffey, Claire Cochran, Katie Gillies

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

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Abstract

Clinical trials comprise multiple processes at various stages of the trial lifecycle. These processes often involve complex behaviours such as recruiting vulnerable patient populations and clinicians having to deliver complex trial interventions successfully. Few studies have utilised a behavioural framework to assess challenges and develop strategies for effective trial recruitment and delivery of trial interventions. This study reports the application of an innovative methodological approach to understand core trial processes, namely recruitment and intervention delivery, using a behavioural science approach to develop strategies designed to mitigate trial process problems.

Original language	English
Article number	398
Number of pages	16
Journal	Trials
Volume	23
Issue number	1
Early online date	12 May 2022
DOIs	https://doi.org/10.1186/s13063-022-06341-6
Publication status	Published - 12 May 2022

Bibliographical note

Acknowledgements
We thank the UK-REBOA site staf for dedicating their time to be interviewed

Keywords

Trial methodology
Behavioural science
Complex interventions
Process evaluations
Theoretical domains framework

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Behavioural optimisation to address trial conduct challenges: case study in the UK-REBOA trial
Lawrie, L. (Creator), Duncan, E. M. (Creator), Jansen, J. O. (Creator), Campbell, M. K. (Creator), Brunsdon, D. (Creator), Skea, Z. (Creator), Coffey, T. (Creator), Cochran, C. (Creator) & Gillies, K. (Creator), Figshare, 2022
DOI: 10.6084/m9.figshare.c.5993933.v1, https://springernature.figshare.com/collections/Behavioural_optimisation_to_address_trial_conduct_challenges_case_study_in_the_UK-REBOA_trial/5993933/1
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Cite this

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Behavioural optimisation to address trial conduct challenges: case study in the UK-REBOA trial

Abstract

Bibliographical note

Keywords

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Behavioural optimisation to address trial conduct challenges: case study in the UK-REBOA trial

Cite this