@article{6ac4b43f9efc432cba11aa68505e7221,
title = "Biochemical Characterization of a Cyanobactin Arginine-N-Prenylase from the Autumnalamide Biosynthetic Pathway",
abstract = "Cyanobactins are linear and cyclic post-translationally modified peptides. Here we show that the prenyl-D-Arg-containing autumnalamide A is a member of the cyanobactin family. Biochemical assays demonstate that the AutF prenyltransferase targets the guanidinium moiety in arginine and homoarginine and is a useful tool for biotechnological applications. ",
author = "Claudia Clemente and Johnson, {Nicholas Ross} and Xiaodan Ouyang and Popin, {Rafael V.} and Sergio DallʼAngelo and Matti Wahlsten and Jouni Jokela and Alessandro Colombano and Brunello Nardone and Fewer, {David Peter} and Houssen, {Wael E}",
note = "Acknowledgements This project was supported by a fellowship grant from the EPSRC (no. EP/S027246/1, W.E.H.), a training grant from the BBSRC (BB/V509206/1, W.E.H. and S.D.), the Novo Nordisk Foundation (18OC0034838, D.P.F.) and the NordForsk NCoE program “NordAqua” (Project Number 82845, D.P.F.). CC is funded by a PhD studentship from University of Aberdeen. NJ is funded by the IBioIC CTP PhD programme. RVP was funded by the Doctoral Programme in Microbiology and Biotechnology of the University of Helsinki. XO was funded by the China Scholarship Council (Grant 201906150148). We are grateful to Professor James Naismith (University of Oxford) for sharing the construct used to express the macrocyclase PCY1. We thank Dr Huanting Liu (University of St Andrews) for sharing the pEHISTEV-SUMO vector.",
year = "2022",
month = nov,
day = "7",
doi = "10.1039/D2CC01799G",
language = "English",
volume = "58",
pages = "12054--12057",
journal = "Chemical Communications",
issn = "1359-7345",
publisher = "Royal Society of Chemistry",
number = "86",
}